AU4640985A - Benzimidazole derivatives - Google Patents

Benzimidazole derivatives

Info

Publication number
AU4640985A
AU4640985A AU46409/85A AU4640985A AU4640985A AU 4640985 A AU4640985 A AU 4640985A AU 46409/85 A AU46409/85 A AU 46409/85A AU 4640985 A AU4640985 A AU 4640985A AU 4640985 A AU4640985 A AU 4640985A
Authority
AU
Australia
Prior art keywords
benzimidazole derivatives
benzimidazole
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU46409/85A
Inventor
Masatoshi Hayashi
Yutaka Nomura
Susumu Okabe
Masaru Satoh
Tomio Yamakawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Chemiphar Co Ltd
Original Assignee
Nippon Chemiphar Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP59-182400 priority Critical
Priority to JP59182400A priority patent/JPH0430953B2/ja
Priority to JP60061195A priority patent/JPH0764826B2/en
Priority to JP60-61194 priority
Priority to JP60-61195 priority
Priority to JP60061194A priority patent/JPH068283B2/en
Application filed by Nippon Chemiphar Co Ltd filed Critical Nippon Chemiphar Co Ltd
Publication of AU4640985A publication Critical patent/AU4640985A/en
Application status is Abandoned legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28Sulfur atoms
AU46409/85A 1984-08-31 1985-08-19 Benzimidazole derivatives Abandoned AU4640985A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP59-182400 1984-08-31
JP59182400A JPH0430953B2 (en) 1984-08-31 1984-08-31
JP60-61194 1985-03-26
JP60-61195 1985-03-26
JP60061194A JPH068283B2 (en) 1985-03-26 1985-03-26 Benzimidazole - Le derivatives and their preparation as well as anti-ulcer agents containing the same
JP60061195A JPH0764826B2 (en) 1985-03-26 1985-03-26 Benzimidazole derivatives

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU41271/89A Division AU4127189A (en) 1984-08-31 1989-09-11 Benzimidazole derivatives, process for preparing the same and antiulcer agents containing the same

Publications (1)

Publication Number Publication Date
AU4640985A true AU4640985A (en) 1986-03-06

Family

ID=27297422

Family Applications (3)

Application Number Title Priority Date Filing Date
AU46409/85A Abandoned AU4640985A (en) 1984-08-31 1985-08-19 Benzimidazole derivatives
AU41271/89A Abandoned AU4127189A (en) 1984-08-31 1989-09-11 Benzimidazole derivatives, process for preparing the same and antiulcer agents containing the same
AU29750/92A Ceased AU647978B2 (en) 1984-08-31 1992-11-27 Benzimidazole derivatives

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU41271/89A Abandoned AU4127189A (en) 1984-08-31 1989-09-11 Benzimidazole derivatives, process for preparing the same and antiulcer agents containing the same
AU29750/92A Ceased AU647978B2 (en) 1984-08-31 1992-11-27 Benzimidazole derivatives

Country Status (14)

Country Link
KR (1) KR920004936B1 (en)
AR (1) AR242195A1 (en)
AU (3) AU4640985A (en)
BE (1) BE903128A (en)
BR (1) BR8504252A (en)
CH (1) CH665417A5 (en)
DE (1) DE3531487C2 (en)
ES (1) ES8703142A1 (en)
FR (1) FR2569691B1 (en)
GB (1) GB2163747B (en)
IT (1) IT1189601B (en)
MX (1) MX159807A (en)
NL (1) NL8502384A (en)
SE (1) SE500669C2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU594074B2 (en) * 1985-08-14 1990-03-01 Nippon Chemiphar Co. Ltd. Cytoprotective agent for gastrointestinal tract
AU619444B2 (en) * 1986-06-02 1992-01-30 Nippon Chemiphar Co. Ltd. 2-(2-aminobenzylsulfinyl)- benzimidazole derivatives

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GB8417194D0 (en) * 1984-07-05 1984-08-08 Boots Co Plc Therapeutic agents
GB2161160B (en) * 1984-07-06 1989-05-24 Fisons Plc Heterocyclic sulphinyl compounds
CA1341314C (en) 1984-07-06 2001-11-06 David Cox Derivatives of benzimidazole, benzothiazole and benzoxazole
AU5768886A (en) * 1985-05-24 1986-11-27 G.D. Searle & Co. 2-((1-h-benzimidazol-2-ylsulfinyl)methyl)benzenamines
US5869513A (en) * 1985-05-24 1999-02-09 G. D. Searle & Co. 2- (1H-benzimidazol-2-ylsulfinyl)methyl!benzenamines
WO1987001114A2 (en) * 1985-08-21 1987-02-26 Byk Gulden Lomberg Chemische Fabrik Gmbh New amines, process for their manufacture, their use and medicines containing them
AR243167A1 (en) 1985-08-24 1993-07-30 Hoechst Ag Substituted toluidines, process for their preparation, pharmaceutical compositions containing them and their use as gastric secretion inhibitors
EP0251536A1 (en) * 1986-06-24 1988-01-07 FISONS plc Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors
US4687775A (en) * 1986-07-17 1987-08-18 G. D. Searle & Co. 2-[(Imidazo[1,2-a]pyridinylmethyl)sulfinyl]-1H-benzimidazoles
US4772619A (en) * 1986-07-17 1988-09-20 G. D. Searle & Co. [(1H-benzimidazol-2-ylsulfinyl)methyl]-2-pyridinamines
US4721718A (en) * 1986-08-18 1988-01-26 G. D. Searle & Co. 2-[(imidazo[1,2-a]pyridin-3-ylmethyl)sulfinyl]-1H-benzimidazoles useful in the treatment and prevention of ulcers
DE3639926A1 (en) * 1986-11-22 1988-06-01 Hoechst Ag Substituted thienoimidazoltoluidin derivatives, methods for their manufacture, pharmaceutical compositions containing them and their use as gastric acid secretion
IT1222412B (en) * 1987-07-31 1990-09-05 Chiesi Farma Spa Thiomethyl and methyl sulfinyl derivatives to gastric acid antisecretory action, their process of preparation and pharmaceutical compositions containing them
JP2614756B2 (en) * 1988-08-10 1997-05-28 日本ケミファ株式会社 Imidazole derivatives and their preparation as well as anti-ulcer agents containing the same
JPH06298611A (en) * 1993-04-16 1994-10-25 Nippon Chemiphar Co Ltd Antibacterial agents
SE9301489D0 (en) 1993-04-30 1993-04-30 Ab Astra Veterinary composition
SE9402431D0 (en) * 1994-07-08 1994-07-08 Astra Ab New Tablet Formulation
SE9500422D0 (en) * 1995-02-06 1995-02-06 Astra Ab New Oral Pharmaceutical Dosage Forms
SE9500478D0 (en) * 1995-02-09 1995-02-09 Astra Ab New pharmaceutical formulation and process
US5708017A (en) * 1995-04-04 1998-01-13 Merck & Co., Inc. Stable, ready-to-use pharmaceutical paste composition containing proton pump inhibitors
HRP960232A2 (en) * 1995-07-03 1998-02-28 Astra Ab A process for the optical purification of compounds
ES2220989T3 (en) * 1995-09-21 2004-12-16 Pharma Pass Ii Llc New composition containing acid labile and procedure for preparing benzimidazole.
SE9600070D0 (en) 1996-01-08 1996-01-08 Astra Ab New Oral Pharmaceutical Dosage Forms
US6599927B2 (en) 1996-10-11 2003-07-29 Astrazeneca Ab Use of an H+, K+-ATPase inhibitor in the treatment of Widal's Syndrome
EP1003554B1 (en) 1997-07-25 2004-11-03 ALTANA Pharma AG Proton pump inhibitor in therapeutic combination with antibacterial substances
SE9704869D0 (en) * 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulaton II
SE9704870D0 (en) * 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulation in
PT1105105E (en) 1998-08-12 2006-07-31 Altana Pharma Ag Method of oral administration for pyridin-2-ilmetilsulfinyl-1h-benzimidazois
AU1054899A (en) * 1998-11-06 2000-05-29 Dong-A Pharmaceutical Co., Ltd. Method of preparing sulfide derivatives
TWI243672B (en) 1999-06-01 2005-11-21 Astrazeneca Ab New use of compounds as antibacterial agents
IL146504D0 (en) 1999-06-07 2002-07-25 Byk Gulden Lomberg Chem Fab Pharmaceutical compositions containing an acid-labile active compound and processes for the preparation thereof
SE9903831D0 (en) * 1999-10-22 1999-10-22 Astra Ab Formulation of substituted benzimidazoles
SE0000774D0 (en) 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
US6544556B1 (en) 2000-09-11 2003-04-08 Andrx Corporation Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor
SE0101379D0 (en) 2001-04-18 2001-04-18 Diabact Ab The composition that inhibits gastric acid secretion
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
SE0102993D0 (en) 2001-09-07 2001-09-07 Astrazeneca Ab New self-emulsifying drug delivery systems
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
CA2480826C (en) 2002-04-09 2012-02-07 Flamel Technologies Oral pharmaceutical formulation in the form of microcapsule aqueous suspension allowing modified release of active ingredient(s)
WO2003084517A2 (en) 2002-04-09 2003-10-16 Flamel Technologies Oral suspension of amoxicillin capsules
SE0203065D0 (en) 2002-10-16 2002-10-16 Diabact Ab Gastric acid secretion inhibiting composition
EP2112920B1 (en) 2003-06-26 2018-07-25 Intellipharmaceutics Corp. Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
EP1708684A2 (en) 2003-09-26 2006-10-11 Alza Corporation Drug coating providing high drug loading and methods for providing the same
US8541026B2 (en) 2004-09-24 2013-09-24 Abbvie Inc. Sustained release formulations of opioid and nonopioid analgesics
US8394409B2 (en) 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US20060024362A1 (en) 2004-07-29 2006-02-02 Pawan Seth Composition comprising a benzimidazole and process for its manufacture
US7803817B2 (en) 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
US7981908B2 (en) 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
CA2648280C (en) 2006-04-03 2014-03-11 Isa Odidi Controlled release delivery device comprising an organosol coat
US20140010860A1 (en) 2006-05-12 2014-01-09 Isa Odidi Abuse and alcohol resistant drug composition
US9233092B2 (en) 2006-07-25 2016-01-12 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion using derivatives of small dicarboxylic acids in combination with PPI
US9205094B2 (en) 2006-12-22 2015-12-08 Ironwood Pharmaceuticals, Inc. Compositions comprising bile acid sequestrants for treating esophageal disorders
US9220698B2 (en) 2008-09-09 2015-12-29 Pozen Inc. Method for delivering a pharmaceutical composition to patient in need thereof
KR20120030106A (en) 2009-06-25 2012-03-27 아스트라제네카 아베 Method for treating a patient at risk for developing an nsaid-associated ulcer
WO2011080500A2 (en) 2009-12-29 2011-07-07 Orexo Ab New pharmaceutical dosage form for the treatment of gastric acid-related disorders
WO2011080501A2 (en) 2009-12-29 2011-07-07 Orexo Ab New pharmaceutical dosage form for the treatment of gastric acid-related disorders
WO2011080502A2 (en) 2009-12-29 2011-07-07 Orexo Ab New pharmaceutical dosage form for the treatment of gastric acid-related disorders
WO2012027331A1 (en) 2010-08-27 2012-03-01 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
EP2601947A1 (en) 2011-12-05 2013-06-12 Abo Bakr Mohammed Ali Al-Mehdar Fixed-dose combination for treatment of helicobacter pylori associated diseases
CN104519888A (en) 2011-12-28 2015-04-15 波曾公司 Improved compositions and methods for delivery of omeprazole plus acetylsalicylic acid
EP2945614A1 (en) 2013-01-15 2015-11-25 Ironwood Pharmaceuticals, Inc. Gastro-retentive sustained-release oral dosage form of a bile acid sequestrant
EP2801565B1 (en) * 2013-05-06 2015-07-22 King Saud University Compounds for use as anti-ulcer agent and/or anti-Helicobacter pylori agent and pharmaceutical compositions thereof
WO2016126625A1 (en) 2015-02-03 2016-08-11 Ironwood Pharmaceuticals, Inc. Methods of treating upper gastrointestinal disorders in ppi refractory gerd

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CA1341314C (en) * 1984-07-06 2001-11-06 David Cox Derivatives of benzimidazole, benzothiazole and benzoxazole

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU594074B2 (en) * 1985-08-14 1990-03-01 Nippon Chemiphar Co. Ltd. Cytoprotective agent for gastrointestinal tract
AU619444B2 (en) * 1986-06-02 1992-01-30 Nippon Chemiphar Co. Ltd. 2-(2-aminobenzylsulfinyl)- benzimidazole derivatives

Also Published As

Publication number Publication date
ES546445D0 (en)
SE8504048D0 (en) 1985-08-30
GB2163747B (en) 1989-02-08
CH665417A5 (en) 1988-05-13
NL8502384A (en) 1986-03-17
DE3531487C2 (en) 1995-08-17
IT8567743D0 (en) 1985-08-30
BE903128A1 (en)
SE8504048L (en) 1986-03-01
AU2975092A (en) 1993-01-28
ES8703142A1 (en) 1986-11-16
AU4127189A (en) 1989-12-21
DE3531487A1 (en) 1986-03-13
AU647978B2 (en) 1994-03-31
SE500669C2 (en) 1994-08-08
FR2569691A1 (en) 1986-03-07
IT1189601B (en) 1988-02-04
GB8521493D0 (en) 1985-10-02
ES546445A0 (en) 1986-11-16
BE903128A (en) 1985-12-16
BR8504252A (en) 1986-06-17
KR920004936B1 (en) 1992-06-22
GB2163747A (en) 1986-03-05
AR242195A1 (en) 1993-03-31
FR2569691B1 (en) 1989-08-04
MX159807A (en) 1989-08-31

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