EA200802204A1 - Применение ингибиторов dpp iv - Google Patents

Применение ингибиторов dpp iv

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Publication number
EA200802204A1
EA200802204A1 EA200802204A EA200802204A EA200802204A1 EA 200802204 A1 EA200802204 A1 EA 200802204A1 EA 200802204 A EA200802204 A EA 200802204A EA 200802204 A EA200802204 A EA 200802204A EA 200802204 A1 EA200802204 A1 EA 200802204A1
Authority
EA
Eurasian Patent Office
Prior art keywords
dpp
inhibitors
application
functional disorders
physiological functional
Prior art date
Application number
EA200802204A
Other languages
English (en)
Other versions
EA036523B1 (ru
Inventor
Клаус Дуги
Франк Химмельсбах
Михаэль Марк
Original Assignee
Бёрингер Ингельхайм Интернациональ Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38235138&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200802204(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Бёрингер Ингельхайм Интернациональ Гмбх filed Critical Бёрингер Ингельхайм Интернациональ Гмбх
Publication of EA200802204A1 publication Critical patent/EA200802204A1/ru
Publication of EA036523B1 publication Critical patent/EA036523B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine

Abstract

В заявке описано применение выбранных ингибиторов DPP IV для лечения физиологических функциональных нарушений, а также для снижения риска возникновения таких физиологических функциональных нарушений у пациентов соответствующих групп риска. В заявке описано также применение указанных ингибиторов DPP IV в сочетании с действующими веществами других классов, что позволяет добиться лучших результатов в лечении подобных физиологических функциональных нарушений. Для подобного применения ингибиторов DPP IV на их основе можно приготавливать соответствующие лекарственные средства.
EA200802204A 2006-05-04 2007-05-03 Применение ингибитора dpp iv EA036523B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06009203 2006-05-04
PCT/EP2007/054270 WO2007128761A2 (de) 2006-05-04 2007-05-03 Verwendungen von dpp iv inhibitoren

Publications (2)

Publication Number Publication Date
EA200802204A1 true EA200802204A1 (ru) 2009-04-28
EA036523B1 EA036523B1 (ru) 2020-11-19

Family

ID=38235138

Family Applications (3)

Application Number Title Priority Date Filing Date
EA200802204A EA036523B1 (ru) 2006-05-04 2007-05-03 Применение ингибитора dpp iv
EA202091999A EA202091999A3 (ru) 2006-05-04 2007-05-03 Применение ингибиторов dpp iv
EA201300213A EA036618B1 (ru) 2006-05-04 2007-05-03 Способ терапевтического лечения выраженного диабета 2 типа с помощью ингибитора dpp iv

Family Applications After (2)

Application Number Title Priority Date Filing Date
EA202091999A EA202091999A3 (ru) 2006-05-04 2007-05-03 Применение ингибиторов dpp iv
EA201300213A EA036618B1 (ru) 2006-05-04 2007-05-03 Способ терапевтического лечения выраженного диабета 2 типа с помощью ингибитора dpp iv

Country Status (35)

Country Link
US (8) US8232281B2 (ru)
EP (5) EP2407168A1 (ru)
JP (12) JP5734564B2 (ru)
KR (9) KR20220140016A (ru)
CN (8) CN104095854A (ru)
AR (1) AR060757A1 (ru)
AU (1) AU2007247141B2 (ru)
BR (1) BRPI0711308A2 (ru)
CA (4) CA2875706C (ru)
CL (3) CL2012002528A1 (ru)
CY (1) CY1115350T1 (ru)
DK (1) DK2015754T3 (ru)
EA (3) EA036523B1 (ru)
EC (1) ECSP088866A (ru)
ES (2) ES2474866T3 (ru)
HK (1) HK1204548A1 (ru)
HR (1) HRP20140645T1 (ru)
IL (1) IL195031A0 (ru)
ME (1) ME01787B (ru)
MX (3) MX358618B (ru)
MY (3) MY172012A (ru)
NO (1) NO345061B1 (ru)
NZ (2) NZ609765A (ru)
PE (2) PE20080251A1 (ru)
PH (2) PH12013501790B1 (ru)
PL (1) PL2015754T3 (ru)
PT (2) PT2015754E (ru)
RS (1) RS53272B (ru)
SG (1) SG171648A1 (ru)
SI (1) SI2015754T1 (ru)
TW (2) TWI500423B (ru)
UA (1) UA102669C2 (ru)
UY (1) UY30321A1 (ru)
WO (1) WO2007128761A2 (ru)
ZA (1) ZA200808282B (ru)

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