ATE165360T1 - Triazolylthiomethylthiocephalosporin- hydrochlorid, sein kristallines hydrat und seine herstellung - Google Patents

Triazolylthiomethylthiocephalosporin- hydrochlorid, sein kristallines hydrat und seine herstellung

Info

Publication number
ATE165360T1
ATE165360T1 AT93305864T AT93305864T ATE165360T1 AT E165360 T1 ATE165360 T1 AT E165360T1 AT 93305864 T AT93305864 T AT 93305864T AT 93305864 T AT93305864 T AT 93305864T AT E165360 T1 ATE165360 T1 AT E165360T1
Authority
AT
Austria
Prior art keywords
crystalline hydrate
hydrochloride
triazolylthiomethylthiocephalosporine
preparation
useful
Prior art date
Application number
AT93305864T
Other languages
English (en)
Inventor
Hisanori Takahashi
Yutaka Ide
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Application granted granted Critical
Publication of ATE165360T1 publication Critical patent/ATE165360T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT93305864T 1992-07-31 1993-07-26 Triazolylthiomethylthiocephalosporin- hydrochlorid, sein kristallines hydrat und seine herstellung ATE165360T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP20496592 1992-07-31

Publications (1)

Publication Number Publication Date
ATE165360T1 true ATE165360T1 (de) 1998-05-15

Family

ID=16499234

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93305864T ATE165360T1 (de) 1992-07-31 1993-07-26 Triazolylthiomethylthiocephalosporin- hydrochlorid, sein kristallines hydrat und seine herstellung

Country Status (23)

Country Link
US (1) US5407929A (de)
EP (1) EP0581552B1 (de)
KR (1) KR100245938B1 (de)
CN (1) CN1037683C (de)
AT (1) ATE165360T1 (de)
AU (1) AU657866B2 (de)
BR (1) BR9303235A (de)
CA (1) CA2101502A1 (de)
DE (1) DE69318077T2 (de)
ES (1) ES2115725T3 (de)
FI (1) FI933391L (de)
GR (1) GR3026699T3 (de)
HU (1) HU219637B (de)
IL (1) IL106516A (de)
MX (1) MX9304611A (de)
NO (1) NO303734B1 (de)
NZ (1) NZ248285A (de)
PH (1) PH30109A (de)
PL (2) PL172830B1 (de)
RU (1) RU2118959C1 (de)
TW (1) TW307769B (de)
UA (1) UA37181C2 (de)
ZA (1) ZA935529B (de)

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EA007485B1 (ru) * 2001-02-24 2006-10-27 Берингер Ингельхайм Фарма Гмбх Унд Ко. Кг Производные ксантина, способ их получения, фармацевтическая композиция на их основе и способ ее получения
AT413282B (de) * 2002-02-01 2006-01-15 Sandoz Ag Kristalline salze der 7-(((5-amino-1,2,4-thiadiazol-3-yl) (fluoromethoxy-imino)acetyl)amino)-3- ((imino-1-piperazinylmethyl)
KR20030076759A (ko) * 2002-03-21 2003-09-29 주식회사 엘지생명과학 신규 세팔로스포린 화합물 및 그의 제조 방법
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
US6727277B1 (en) 2002-11-12 2004-04-27 Kansas State University Research Foundation Compounds affecting cholesterol absorption
EP1592668A1 (de) 2003-02-12 2005-11-09 Ciba SC Holding AG Kristalline formen von pitavastatin-calcium
PL1606293T3 (pl) 2003-03-27 2010-01-29 Basilea Pharmaceutica Ag Cefalosporyna w postaci krystalicznej
US7501426B2 (en) * 2004-02-18 2009-03-10 Boehringer Ingelheim International Gmbh 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
DE102005035891A1 (de) * 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
EP1852108A1 (de) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG Zusammensetzungen von DPP-IV-Inhibitoren
PE20110235A1 (es) 2006-05-04 2011-04-14 Boehringer Ingelheim Int Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
MX2008014024A (es) 2006-05-04 2008-11-14 Boehringer Ingelheim Int Formas poliformas.
EP3542801A1 (de) * 2007-08-17 2019-09-25 Boehringer Ingelheim International GmbH Purinderivate zur verwendung bei der behandlung von fap-bedingten erkrankungen
PE20140960A1 (es) * 2008-04-03 2014-08-15 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
PE20100156A1 (es) * 2008-06-03 2010-02-23 Boehringer Ingelheim Int Tratamiento de nafld
KR20200118243A (ko) 2008-08-06 2020-10-14 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
CN103816158A (zh) * 2008-08-15 2014-05-28 勃林格殷格翰国际有限公司 用于治疗fab-相关疾病的嘌呤衍生物
CN102149407A (zh) 2008-09-10 2011-08-10 贝林格尔.英格海姆国际有限公司 治疗糖尿病和相关病症的组合疗法
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
CN107011345A (zh) 2008-12-23 2017-08-04 勃林格殷格翰国际有限公司 有机化合物的盐形式
TW201036975A (en) 2009-01-07 2010-10-16 Boehringer Ingelheim Int Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy
EP2504002B1 (de) 2009-11-27 2019-10-09 Boehringer Ingelheim International GmbH Behandlung von genotypisierten diabetes-patienten mit dpp-iv-hemmern wie etwa linagliptin
KR101927068B1 (ko) 2010-05-05 2018-12-10 베링거 인겔하임 인터내셔날 게엠베하 체중 감소 치료에 후속하는 dpp-4 억제제에 의한 순차적 병용 요법
KR20200028498A (ko) 2010-06-24 2020-03-16 베링거 인겔하임 인터내셔날 게엠베하 당뇨병 요법
AR083878A1 (es) 2010-11-15 2013-03-27 Boehringer Ingelheim Int Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
HUE061596T2 (hu) 2011-07-15 2023-07-28 Boehringer Ingelheim Int Szubsztituált dimer kinazolin származék, annak elõállítása és alkalmazása az I. és II. típusú cukorbetegség kezelésére szolgáló gyógyszerkészítményekben
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
US20130303462A1 (en) 2012-05-14 2013-11-14 Boehringer Ingelheim International Gmbh Use of a dpp-4 inhibitor in podocytes related disorders and/or nephrotic syndrome
ES2929025T3 (es) 2012-05-14 2022-11-24 Boehringer Ingelheim Int Linagliptina, un derivado de xantina como inhibidor de dpp-4, para su uso en el tratamiento del SRIS y/o de la septicemia
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
EP3110449B1 (de) 2014-02-28 2023-06-28 Boehringer Ingelheim International GmbH Medizinische verwendung eines dpp-4-inhibitors
BR112018072401A2 (pt) 2016-06-10 2019-02-19 Boehringer Ingelheim International Gmbh combinações de linagliptina e metformina

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES475573A1 (es) * 1977-07-12 1980-01-16 Fujisawa Pharmaceutical Co Un procedimiento para preparar nuevos compuestos de cefem
IE65926B1 (en) * 1990-07-19 1995-11-29 Shionogi & Co Thioalkylthio cephalosporin derivatives

Also Published As

Publication number Publication date
DE69318077T2 (de) 1998-10-29
AU657866B2 (en) 1995-03-23
HU219637B (hu) 2001-06-28
NZ248285A (en) 1994-07-26
TW307769B (de) 1997-06-11
CN1089948A (zh) 1994-07-27
NO932745L (no) 1994-02-01
NO303734B1 (no) 1998-08-24
DE69318077D1 (de) 1998-05-28
MX9304611A (es) 1994-02-28
FI933391A7 (fi) 1994-02-01
PL299870A1 (en) 1994-02-07
BR9303235A (pt) 1994-03-01
GR3026699T3 (en) 1998-07-31
US5407929A (en) 1995-04-18
FI933391L (fi) 1994-02-01
RU2118959C1 (ru) 1998-09-20
PL172835B1 (pl) 1997-12-31
EP0581552B1 (de) 1998-04-22
IL106516A (en) 1998-06-15
HUT68602A (en) 1995-06-28
NO932745D0 (no) 1993-07-30
HU9302194D0 (en) 1993-10-28
KR100245938B1 (ko) 2000-04-01
EP0581552A3 (en) 1994-06-01
IL106516A0 (en) 1993-11-15
CA2101502A1 (en) 1994-02-01
FI933391A0 (fi) 1993-07-29
PL172830B1 (pl) 1997-12-31
ES2115725T3 (es) 1998-07-01
KR940005636A (ko) 1994-03-22
EP0581552A2 (de) 1994-02-02
UA37181C2 (uk) 2001-05-15
CN1037683C (zh) 1998-03-11
AU4422793A (en) 1994-02-03
ZA935529B (en) 1994-02-24
PH30109A (en) 1996-12-27

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee