PL1606293T3 - Cefalosporyna w postaci krystalicznej - Google Patents

Cefalosporyna w postaci krystalicznej

Info

Publication number
PL1606293T3
PL1606293T3 PL04720595T PL04720595T PL1606293T3 PL 1606293 T3 PL1606293 T3 PL 1606293T3 PL 04720595 T PL04720595 T PL 04720595T PL 04720595 T PL04720595 T PL 04720595T PL 1606293 T3 PL1606293 T3 PL 1606293T3
Authority
PL
Poland
Prior art keywords
crystalline form
cephalosporin
formula
mrsa
potent
Prior art date
Application number
PL04720595T
Other languages
English (en)
Inventor
Joerg Berghausen
Original Assignee
Basilea Pharmaceutica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica Ag filed Critical Basilea Pharmaceutica Ag
Publication of PL1606293T3 publication Critical patent/PL1606293T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/48—Methylene radicals, substituted by hetero rings
    • C07D501/56—Methylene radicals, substituted by hetero rings with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL04720595T 2003-03-27 2004-03-15 Cefalosporyna w postaci krystalicznej PL1606293T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03006815 2003-03-27
EP04720595A EP1606293B1 (en) 2003-03-27 2004-03-15 Cephalosporin in crystalline form
PCT/EP2004/002667 WO2004085444A1 (en) 2003-03-27 2004-03-15 Cephalosporin in crystalline form

Publications (1)

Publication Number Publication Date
PL1606293T3 true PL1606293T3 (pl) 2010-01-29

Family

ID=33040912

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04720595T PL1606293T3 (pl) 2003-03-27 2004-03-15 Cefalosporyna w postaci krystalicznej

Country Status (21)

Country Link
US (2) US7531650B2 (pl)
EP (1) EP1606293B1 (pl)
JP (1) JP5230934B2 (pl)
KR (1) KR101121942B1 (pl)
CN (1) CN1751051B (pl)
AT (1) ATE440101T1 (pl)
AU (1) AU2004224181B2 (pl)
BR (1) BRPI0408716B1 (pl)
CA (1) CA2519272C (pl)
CY (1) CY1109615T1 (pl)
DE (1) DE602004022643D1 (pl)
DK (1) DK1606293T3 (pl)
ES (1) ES2329244T3 (pl)
HK (1) HK1085479A1 (pl)
MX (1) MXPA05010083A (pl)
PL (1) PL1606293T3 (pl)
PT (1) PT1606293E (pl)
SI (1) SI1606293T1 (pl)
TW (1) TWI346117B (pl)
WO (1) WO2004085444A1 (pl)
ZA (1) ZA200507760B (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007006018A (es) * 2004-11-30 2007-06-07 Astellas Pharma Inc Suspension farmaceutica oral novedosa de cristal de cefdinir.

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE758350A (fr) * 1969-12-30 1971-05-03 Pfizer Procede de fabrication des sels mono- et bi-metalliques alcalins de l'alpha-carboxybenzylpenicilline
US3697506A (en) * 1970-08-07 1972-10-10 Pfizer Crystalline alkali metal salts of {60 -carboxybenzylpenicillin and process therefor
JPS5579393A (en) 1978-12-11 1980-06-14 Takeda Chem Ind Ltd Cephalosporin derivative and its preparation
GR78221B (pl) * 1980-02-01 1984-09-26 Ciba Geigy Ag
US4432987A (en) * 1982-04-23 1984-02-21 Pfizer Inc. Crystalline benzenesulfonate salts of sultamicillin
FR2532315A1 (fr) 1982-08-27 1984-03-02 Rhone Poulenc Sante Formes cristallisees de sels d'addition avec des acides, de l'((amino-2-thiazolyl-4)-2 methoxyimino-2 acetamido)-7 carboxy-2 (dioxo-5,6 formylmethyl-4 tetrahydro-1,4,5,6 triazine-1,2,4 yl-3) thio-2 vinyl)-3 oxo-8 thia-5 aza-1 bicyclo(4.2.0) octene-2 isomere syn, forme e et leur preparation
US4634556A (en) * 1985-05-10 1987-01-06 Schering Corporation Crystalline sodium (5R, 6S, 8R)-6-(1-hydroxyethyl)-2-(2-carbamoyloxyethylthio)-penem-3-carboxylate and process for making same
AU615966B2 (en) * 1987-12-04 1991-10-17 Takeda Chemical Industries Ltd. Crystals of cephem hydrochloride
JPH02101081A (ja) 1988-10-08 1990-04-12 Meiji Seika Kaisha Ltd セファロスポリン誘導体結晶性二塩酸塩及びその製造法
CA2011116C (en) * 1989-03-06 1999-11-16 Murray A. Kaplan Lyophilized bmy-28142 dihydrochloride for parenteral use
US5492903A (en) * 1990-06-19 1996-02-20 Takeda Chemical Industries Ltd. Crystalline esters of (+)-(5R, 6S)-6-[(R)-1-hydroxyethyl]-3-(3-pyridyl)-7-oxo-4-thia-1-azabicyclo[3.2.0]he
JP2575590B2 (ja) * 1992-07-31 1997-01-29 塩野義製薬株式会社 トリアゾリルチオメチルチオセファロスポリン塩酸塩およびその水和物結晶ならびにそれらの製法
EP0581552B1 (en) 1992-07-31 1998-04-22 Shionogi & Co., Ltd. Triazolylthiomethylthio cephalosporin hyrochloride, its crystalline hydrate and the production of the same
SK283674B6 (sk) * 1993-03-12 2003-11-04 Pharmacia & Upjohn Company Kryštalická voľná kyselina ceftiofuru a spôsob jej prípravy a farmaceutická kompozícia, ktorá ju obsahuje
AU714735B2 (en) * 1996-09-20 2000-01-13 Meiji Seika Pharma Co., Ltd. A crystalline substance of cefditoren pivoxyl and the production of the same
TW415949B (en) * 1996-12-19 2000-12-21 Hoffmann La Roche Vinyl pyrrolidine cephalosporin derivatives with basic substituents
US6232306B1 (en) * 1998-06-15 2001-05-15 Hoffmann-La Roche Inc. Derivatives of 3-(2-oxo-[1,3′]bipyrrolidinyl-3-ylidenemethyl)-cephams
IL139872A0 (en) * 1998-06-15 2002-02-10 Hoffmann La Roche Derivatives of 3-(2-oxo-[1,3'] bipyrrolidinyl-3-ylidenemethyl) cephems
US6504025B2 (en) * 2000-05-24 2003-01-07 Basilea Pharmaceutica Ag Process for the preparation of vinyl-pyrrolidinone cephalosporin derivatives
USRE40794E1 (en) * 2001-09-26 2009-06-23 Merck & Co., Inc. Crystalline forms of carbapenem antibiotics and methods of preparation

Also Published As

Publication number Publication date
DE602004022643D1 (de) 2009-10-01
KR101121942B1 (ko) 2012-03-09
CN1751051A (zh) 2006-03-22
JP5230934B2 (ja) 2013-07-10
ES2329244T3 (es) 2009-11-24
US20060167242A1 (en) 2006-07-27
ZA200507760B (en) 2007-06-27
KR20050111787A (ko) 2005-11-28
US8093377B2 (en) 2012-01-10
EP1606293A1 (en) 2005-12-21
SI1606293T1 (sl) 2009-10-31
AU2004224181A1 (en) 2004-10-07
CA2519272C (en) 2010-06-08
BRPI0408716A (pt) 2006-03-07
US7531650B2 (en) 2009-05-12
MXPA05010083A (es) 2005-11-23
TW200502237A (en) 2005-01-16
BRPI0408716B1 (pt) 2017-08-29
DK1606293T3 (da) 2009-10-05
AU2004224181B2 (en) 2011-06-02
CY1109615T1 (el) 2014-08-13
EP1606293B1 (en) 2009-08-19
US20090192306A1 (en) 2009-07-30
HK1085479A1 (en) 2006-08-25
BRPI0408716B8 (pl) 2021-05-25
ATE440101T1 (de) 2009-09-15
CN1751051B (zh) 2010-06-09
WO2004085444A1 (en) 2004-10-07
PT1606293E (pt) 2009-10-14
JP2006521309A (ja) 2006-09-21
CA2519272A1 (en) 2004-10-07
TWI346117B (en) 2011-08-01

Similar Documents

Publication Publication Date Title
WO2007004028A3 (en) Processes for the preparation of penems and its intermediate
HK1128469A1 (en) Dual action antibiotics
HUP0400446A2 (hu) Azitromicin kristályformái
WO2003106456A3 (en) NEW COMPOUNDS
UA101966C2 (en) Beta-lactamase inhibitors
SI1709044T2 (sl) Oksazolidinon-kinolonski hibridni antibiotiki
MY122829A (en) Linezolid-crystal form ii
ATE353894T1 (de) Acyloxymethylcarbamat-prodrugs von oxazolidinonen
NZ545472A (en) 7-(4-substituted-3-cyclopropylaminomethyl-1-pyrrolidinyl)quinolonecarboxylic acid derivative
TW200716102A (en) Bicyclic 6-alkylidene-penems as class-D β -lactamases inhibitors
EP1784407A4 (en) 2-ARYLMETHYLAZETIDINE CARBAPENEM DERIVATIVES AND PREPARATION THEREOF
EP4272831A3 (en) Diazabicyclooctanones as inhibitors of serine beta-lactamases
WO2003020732A3 (en) 7-alkylidene-3-substituted-3-cephem-4-carboxylates as beta-lactamase inhibitors.
HK1085479A1 (en) Cephalosporin in crystalline form
PT1289998E (pt) Novo processo para a preparacao de derivados de vinil-pirrolidinona cefalosporina
TW200727897A (en) Bicyclic 6-alkylidene-penem β-lactamase inhibitors and β-lactam antibiotic combination: a broad spectrum antibiotic
TW200745053A (en) 9-Aminocarbonylsubstituted derivatives of glycylcyclines
EP1797879A4 (en) NEW ANTIMICROBIAL MEDICAMENT
EP0911030A3 (en) Antimicrobial composition comprising a vinyyl pyrrolidinon derivative and a carbapenem antibiotic or a beta-lactamase inhibitor
EA202190444A1 (ru) Диазабициклооктаноны в качестве ингибиторов сериновых бета-лактамаз
WO2007139729A8 (en) Novel sulfonamidomethylphosphonate inhibitors of beta-lactamase
GR1003520B (el) Μεθοδος χρησης ενωσεων φλουοροκινολονης εναντια σε νοσοκομειακα αρνητικα κατα gramμ παθογενων βακτηριδιων
WO2003068791A3 (en) Macrolides with activity against methicillin-resistant staphylococcus aureus