ATE353894T1 - Acyloxymethylcarbamat-prodrugs von oxazolidinonen - Google Patents
Acyloxymethylcarbamat-prodrugs von oxazolidinonenInfo
- Publication number
- ATE353894T1 ATE353894T1 AT04769372T AT04769372T ATE353894T1 AT E353894 T1 ATE353894 T1 AT E353894T1 AT 04769372 T AT04769372 T AT 04769372T AT 04769372 T AT04769372 T AT 04769372T AT E353894 T1 ATE353894 T1 AT E353894T1
- Authority
- AT
- Austria
- Prior art keywords
- oxazolidinones
- carbamat
- acyloxymethyl
- prodrugs
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50532903P | 2003-09-23 | 2003-09-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE353894T1 true ATE353894T1 (de) | 2007-03-15 |
Family
ID=34375571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04769372T ATE353894T1 (de) | 2003-09-23 | 2004-09-13 | Acyloxymethylcarbamat-prodrugs von oxazolidinonen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7265140B2 (de) |
| EP (1) | EP1668005B1 (de) |
| JP (1) | JP2007505890A (de) |
| AT (1) | ATE353894T1 (de) |
| BR (1) | BRPI0414694A (de) |
| CA (1) | CA2539848A1 (de) |
| DE (1) | DE602004004808T2 (de) |
| ES (1) | ES2278342T3 (de) |
| MX (1) | MXPA06003124A (de) |
| WO (1) | WO2005028473A1 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0413756A (pt) * | 2003-08-20 | 2006-10-31 | Xenoport Inc | composto, métodos para tratar ou evitar espasticidade ou um sintoma de espasticidade, doença de refluxo gastro-esofágico, vìcio em droga, vìcio em ou abuso de álcool, ou vìcio em ou abuso de nicotina, e tosse ou êmese em um paciente, e, composição farmacêutica |
| CN102702065A (zh) | 2003-12-30 | 2012-10-03 | 什诺波特有限公司 | 酰氧基烃基氨基甲酸酯前药及其中间体的合成 |
| WO2005113520A1 (en) * | 2004-05-20 | 2005-12-01 | Pharmacia & Upjohn Company Llc | Substituted 2,3,5-trifluorphenyl oxazolidinones for use as antibacterial agents |
| DE102006007146A1 (de) * | 2006-02-16 | 2007-08-23 | Bayer Healthcare Ag | Aminoacyl-Prodrugs |
| KR20080107408A (ko) | 2006-03-07 | 2008-12-10 | 브리스톨-마이어스 스큅 컴퍼니 | 키나제 억제제로서 유용한 피롤로트리아진 아닐린 전구약물화합물 |
| US7776855B2 (en) | 2006-07-27 | 2010-08-17 | Janssen Pharmaceutica N.V. | Antimicrobial oxazolidinone prodrugs |
| DE102006039589A1 (de) * | 2006-08-24 | 2008-03-06 | Bayer Healthcare Ag | Aminoacyl-Prodrugs II |
| DE102007028407A1 (de) * | 2007-06-20 | 2008-12-24 | Bayer Healthcare Ag | Substituierte Oxazolidinone und ihre Verwendung |
| DE102007028319A1 (de) * | 2007-06-20 | 2008-12-24 | Bayer Healthcare Ag | Substituierte Oxazolidinone und ihre Verwendung |
| DE102007032344A1 (de) | 2007-07-11 | 2009-01-15 | Bayer Healthcare Ag | Prodrug-Derivate von 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin-3-carboxamid |
| DE102007032347A1 (de) * | 2007-07-11 | 2009-01-15 | Bayer Healthcare Ag | Aminoacyl-Prodrugs |
| DE102007032345A1 (de) | 2007-07-11 | 2009-01-15 | Bayer Healthcare Ag | Aminoacyl-Prodrugs |
| WO2010047737A2 (en) | 2008-09-02 | 2010-04-29 | Micurx Pharmaceuticals, Inc. | Antimicrobial indoline compounds for treatment of bacterial infections |
| CN101798302B (zh) | 2009-02-06 | 2014-11-05 | 上海盟科药业有限公司 | 抗生素类药物1-(邻-氟苯基)二氢吡啶酮的合成及生产的方法和工艺 |
| DE102010028362A1 (de) | 2010-04-29 | 2011-11-03 | Bayer Schering Pharma Aktiengesellschaft | Herstellverfahren |
| US20120065170A1 (en) | 2010-09-10 | 2012-03-15 | Micurx Pharmaceuticals, Inc. | Antimicrobial Cyclocarbonyl Heterocyclic Compounds For Treatment Of Bacterial Infections |
| EP2790734B1 (de) | 2011-12-15 | 2019-02-20 | Alkermes Pharma Ireland Limited | Prodrugs von sekundären aminverbindungen |
| WO2014022728A1 (en) | 2012-08-02 | 2014-02-06 | Endo Pharmaceuticals, Inc | Substituted 5 - (quinazolin - 2 - yl) pyrimidin- 2 -amine derivatives useful as pi3k/mtor inhibitors for the treatment of cancer |
| EP3107923B1 (de) | 2014-02-21 | 2021-11-03 | Shanghai MicuRx Pharmaceutical Co., Ltd. | Wasserlösliche o-carbonyl-phosphoramidat-prodrugs zur therapeutischen verabreichung |
| GB201518950D0 (en) | 2015-10-27 | 2015-12-09 | Glaxosmithkline Ip Dev Ltd | Compound |
| ES2965965T3 (es) * | 2017-08-25 | 2024-04-17 | Guangzhou Henovcom Bioscience Co Ltd | Profármaco de rasagilina de acción prolongada, método de preparación y uso del mismo |
| CN118317970A (zh) * | 2021-11-29 | 2024-07-09 | 兆维生物科技公司 | 2'乙酰基-酯保护的核苷的合成 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9610474A (pt) | 1995-09-01 | 1999-03-02 | Upjohn Co | Feniloxazolidinonas tendo uma ligação c-c a anéis heterocíclicos com 4-8 membros |
| CN1322204A (zh) * | 1998-11-27 | 2001-11-14 | 法玛西雅厄普约翰美国公司 | 具有硫代羰基官能团的噁唑烷酮抗菌剂 |
| CZ20022142A3 (cs) * | 1999-12-21 | 2002-11-13 | Pharmacia & Upjohn Company | Oxazolidinony mající sulfoximinovou funkční skupinu |
| GB0108793D0 (en) * | 2001-04-07 | 2001-05-30 | Astrazeneca Ab | Chemical compounds |
| GB0108764D0 (en) * | 2001-04-07 | 2001-05-30 | Astrazeneca Ab | Chemical compounds |
| MXPA04006600A (es) * | 2002-01-24 | 2004-10-04 | Upjohn Co | Dihidrotiazina-y dihidrotiopiran-oxazolidinonas antimicrobianas. |
| TW200403240A (en) * | 2002-06-28 | 2004-03-01 | Upjohn Co | Difluorothioacetamides of oxazolidinones as antibacterial agents |
-
2004
- 2004-09-09 US US10/937,187 patent/US7265140B2/en not_active Expired - Fee Related
- 2004-09-13 BR BRPI0414694-8A patent/BRPI0414694A/pt not_active IP Right Cessation
- 2004-09-13 AT AT04769372T patent/ATE353894T1/de not_active IP Right Cessation
- 2004-09-13 WO PCT/IB2004/002983 patent/WO2005028473A1/en active IP Right Grant
- 2004-09-13 DE DE602004004808T patent/DE602004004808T2/de not_active Expired - Fee Related
- 2004-09-13 ES ES04769372T patent/ES2278342T3/es active Active
- 2004-09-13 CA CA002539848A patent/CA2539848A1/en not_active Abandoned
- 2004-09-13 JP JP2006526723A patent/JP2007505890A/ja not_active Withdrawn
- 2004-09-13 MX MXPA06003124A patent/MXPA06003124A/es not_active Application Discontinuation
- 2004-09-13 EP EP04769372A patent/EP1668005B1/de active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA2539848A1 (en) | 2005-03-31 |
| WO2005028473A1 (en) | 2005-03-31 |
| US7265140B2 (en) | 2007-09-04 |
| MXPA06003124A (es) | 2006-06-20 |
| EP1668005B1 (de) | 2007-02-14 |
| ES2278342T3 (es) | 2007-08-01 |
| EP1668005A1 (de) | 2006-06-14 |
| DE602004004808T2 (de) | 2007-12-06 |
| DE602004004808D1 (de) | 2007-03-29 |
| JP2007505890A (ja) | 2007-03-15 |
| BRPI0414694A (pt) | 2006-11-28 |
| US20050267104A1 (en) | 2005-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |