GR3026699T3 - Triazolylthiomethylthio cephalosporin hyrochloride, its crystalline hydrate and the production of the same. - Google Patents
Triazolylthiomethylthio cephalosporin hyrochloride, its crystalline hydrate and the production of the same.Info
- Publication number
- GR3026699T3 GR3026699T3 GR980400753T GR980400753T GR3026699T3 GR 3026699 T3 GR3026699 T3 GR 3026699T3 GR 980400753 T GR980400753 T GR 980400753T GR 980400753 T GR980400753 T GR 980400753T GR 3026699 T3 GR3026699 T3 GR 3026699T3
- Authority
- GR
- Greece
- Prior art keywords
- production
- crystalline hydrate
- triazolylthiomethylthio
- hyrochloride
- cephalosporin
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 229930186147 Cephalosporin Natural products 0.000 title 1
- 229940124587 cephalosporin Drugs 0.000 title 1
- 150000001780 cephalosporins Chemical class 0.000 title 1
- 230000003115 biocidal effect Effects 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20496592 | 1992-07-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR3026699T3 true GR3026699T3 (en) | 1998-07-31 |
Family
ID=16499234
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR980400753T GR3026699T3 (en) | 1992-07-31 | 1998-04-23 | Triazolylthiomethylthio cephalosporin hyrochloride, its crystalline hydrate and the production of the same. |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5407929A (el) |
| EP (1) | EP0581552B1 (el) |
| KR (1) | KR100245938B1 (el) |
| CN (1) | CN1037683C (el) |
| AT (1) | ATE165360T1 (el) |
| AU (1) | AU657866B2 (el) |
| BR (1) | BR9303235A (el) |
| CA (1) | CA2101502A1 (el) |
| DE (1) | DE69318077T2 (el) |
| ES (1) | ES2115725T3 (el) |
| FI (1) | FI933391A (el) |
| GR (1) | GR3026699T3 (el) |
| HU (1) | HU219637B (el) |
| IL (1) | IL106516A (el) |
| MX (1) | MX9304611A (el) |
| NO (1) | NO303734B1 (el) |
| NZ (1) | NZ248285A (el) |
| PH (1) | PH30109A (el) |
| PL (2) | PL172835B1 (el) |
| RU (1) | RU2118959C1 (el) |
| TW (1) | TW307769B (el) |
| UA (1) | UA37181C2 (el) |
| ZA (1) | ZA935529B (el) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA007485B1 (ru) * | 2001-02-24 | 2006-10-27 | Берингер Ингельхайм Фарма Гмбх Унд Ко. Кг | Производные ксантина, способ их получения, фармацевтическая композиция на их основе и способ ее получения |
| AT413282B (de) * | 2002-02-01 | 2006-01-15 | Sandoz Ag | Kristalline salze der 7-(((5-amino-1,2,4-thiadiazol-3-yl) (fluoromethoxy-imino)acetyl)amino)-3- ((imino-1-piperazinylmethyl) |
| KR20030076759A (ko) * | 2002-03-21 | 2003-09-29 | 주식회사 엘지생명과학 | 신규 세팔로스포린 화합물 및 그의 제조 방법 |
| US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
| US6727277B1 (en) | 2002-11-12 | 2004-04-27 | Kansas State University Research Foundation | Compounds affecting cholesterol absorption |
| JP5192147B2 (ja) | 2003-02-12 | 2013-05-08 | 日産化学工業株式会社 | ピタバスタチンカルシウムの結晶質形態 |
| MXPA05010083A (es) | 2003-03-27 | 2005-11-23 | Basilea Pharmaceutica Ag | Cefalosporina en forma cristalina. |
| US7501426B2 (en) * | 2004-02-18 | 2009-03-10 | Boehringer Ingelheim International Gmbh | 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions |
| DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
| DE102005035891A1 (de) * | 2005-07-30 | 2007-02-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel |
| PE20110235A1 (es) * | 2006-05-04 | 2011-04-14 | Boehringer Ingelheim Int | Combinaciones farmaceuticas que comprenden linagliptina y metmorfina |
| EP1852108A1 (en) | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | DPP IV inhibitor formulations |
| CA2810839A1 (en) | 2006-05-04 | 2007-11-15 | Boehringer Ingelheim International Gmbh | A polymorphic form of 1-[(4-methyl-quinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-(3-(r)-amino-piperidin-1-yl)-xanthine |
| AU2008290582B2 (en) * | 2007-08-17 | 2014-08-14 | Boehringer Ingelheim International Gmbh | Purin derivatives for use in the treatment of fab-related diseases |
| PE20091730A1 (es) | 2008-04-03 | 2009-12-10 | Boehringer Ingelheim Int | Formulaciones que comprenden un inhibidor de dpp4 |
| PE20100156A1 (es) * | 2008-06-03 | 2010-02-23 | Boehringer Ingelheim Int | Tratamiento de nafld |
| BRPI0916997A2 (pt) | 2008-08-06 | 2020-12-15 | Boehringer Ingelheim International Gmbh | Inibidor de dpp-4 e seu uso |
| UY32030A (es) | 2008-08-06 | 2010-03-26 | Boehringer Ingelheim Int | "tratamiento para diabetes en pacientes inapropiados para terapia con metformina" |
| MX2011001525A (es) * | 2008-08-15 | 2011-03-29 | Boehringer Ingelheim Int | Derivados de purina para su uso en el tratamiento de enfermedades relacionadas con fab. |
| CN102149407A (zh) | 2008-09-10 | 2011-08-10 | 贝林格尔.英格海姆国际有限公司 | 治疗糖尿病和相关病症的组合疗法 |
| US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
| BRPI0923121A2 (pt) | 2008-12-23 | 2015-08-11 | Boehringer Ingelheim Int | Formas salinas de compostos orgânico |
| AR074990A1 (es) | 2009-01-07 | 2011-03-02 | Boehringer Ingelheim Int | Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina |
| CN107115530A (zh) | 2009-11-27 | 2017-09-01 | 勃林格殷格翰国际有限公司 | 基因型糖尿病患者利用dpp‑iv抑制剂例如利拉利汀的治疗 |
| KR101927068B1 (ko) | 2010-05-05 | 2018-12-10 | 베링거 인겔하임 인터내셔날 게엠베하 | 체중 감소 치료에 후속하는 dpp-4 억제제에 의한 순차적 병용 요법 |
| CN102971005A (zh) | 2010-06-24 | 2013-03-13 | 贝林格尔.英格海姆国际有限公司 | 糖尿病治疗 |
| US9034883B2 (en) | 2010-11-15 | 2015-05-19 | Boehringer Ingelheim International Gmbh | Vasoprotective and cardioprotective antidiabetic therapy |
| EP3517539B1 (en) | 2011-07-15 | 2022-12-14 | Boehringer Ingelheim International GmbH | Substituted dimeric quinazoline derivative, its preparation and its use in pharmaceutical compositions for the treatment of type i and ii diabetes |
| US9555001B2 (en) | 2012-03-07 | 2017-01-31 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition and uses thereof |
| US20130303462A1 (en) | 2012-05-14 | 2013-11-14 | Boehringer Ingelheim International Gmbh | Use of a dpp-4 inhibitor in podocytes related disorders and/or nephrotic syndrome |
| WO2013174767A1 (en) | 2012-05-24 | 2013-11-28 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference |
| JP6615109B2 (ja) | 2014-02-28 | 2019-12-04 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｄｐｐ−４阻害薬の医学的使用 |
| CA3022202A1 (en) | 2016-06-10 | 2017-12-14 | Boehringer Ingelheim International Gmbh | Combinations of linagliptin and metformin |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE65926B1 (en) * | 1990-07-19 | 1995-11-29 | Shionogi & Co | Thioalkylthio cephalosporin derivatives |
-
1993
- 1993-07-26 TW TW082105942A patent/TW307769B/zh active
- 1993-07-26 DE DE69318077T patent/DE69318077T2/de not_active Expired - Fee Related
- 1993-07-26 ES ES93305864T patent/ES2115725T3/es not_active Expired - Lifetime
- 1993-07-26 EP EP93305864A patent/EP0581552B1/en not_active Expired - Lifetime
- 1993-07-26 AT AT93305864T patent/ATE165360T1/de not_active IP Right Cessation
- 1993-07-27 UA UA93003172A patent/UA37181C2/uk unknown
- 1993-07-27 US US08/097,205 patent/US5407929A/en not_active Expired - Fee Related
- 1993-07-28 AU AU44227/93A patent/AU657866B2/en not_active Ceased
- 1993-07-28 HU HU9302194A patent/HU219637B/hu not_active IP Right Cessation
- 1993-07-28 CA CA002101502A patent/CA2101502A1/en not_active Abandoned
- 1993-07-28 IL IL106516A patent/IL106516A/en not_active IP Right Cessation
- 1993-07-29 PH PH46601A patent/PH30109A/en unknown
- 1993-07-29 NZ NZ24828593A patent/NZ248285A/en unknown
- 1993-07-29 PL PL93299870A patent/PL172835B1/pl unknown
- 1993-07-29 FI FI933391A patent/FI933391A/fi unknown
- 1993-07-29 PL PL93317972A patent/PL172830B1/pl unknown
- 1993-07-30 KR KR1019930014742A patent/KR100245938B1/ko not_active IP Right Cessation
- 1993-07-30 MX MX9304611A patent/MX9304611A/es unknown
- 1993-07-30 NO NO932745A patent/NO303734B1/no unknown
- 1993-07-30 RU RU93047027/04A patent/RU2118959C1/ru not_active IP Right Cessation
- 1993-07-30 ZA ZA935529A patent/ZA935529B/xx unknown
- 1993-07-30 BR BR9303235A patent/BR9303235A/pt not_active Application Discontinuation
- 1993-07-31 CN CN93117437A patent/CN1037683C/zh not_active Expired - Fee Related
-
1998
- 1998-04-23 GR GR980400753T patent/GR3026699T3/el unknown
Also Published As
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