ATE97902T1 - Cephemverbindungen und verfahren zu ihrer herstellung. - Google Patents

Cephemverbindungen und verfahren zu ihrer herstellung.

Info

Publication number
ATE97902T1
ATE97902T1 AT88114406T AT88114406T ATE97902T1 AT E97902 T1 ATE97902 T1 AT E97902T1 AT 88114406 T AT88114406 T AT 88114406T AT 88114406 T AT88114406 T AT 88114406T AT E97902 T1 ATE97902 T1 AT E97902T1
Authority
AT
Austria
Prior art keywords
alkyl
amino
protected
processes
alkylamino
Prior art date
Application number
AT88114406T
Other languages
English (en)
Inventor
Takao Takaya
Kazuo Sakane
Kenzi Miyai
Kohji Kawabata
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Application granted granted Critical
Publication of ATE97902T1 publication Critical patent/ATE97902T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT88114406T 1987-09-07 1988-09-03 Cephemverbindungen und verfahren zu ihrer herstellung. ATE97902T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878721016A GB8721016D0 (en) 1987-09-07 1987-09-07 Cephem compounds
EP88114406A EP0306863B1 (de) 1987-09-07 1988-09-03 Cephemverbindungen und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
ATE97902T1 true ATE97902T1 (de) 1993-12-15

Family

ID=10623397

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88114406T ATE97902T1 (de) 1987-09-07 1988-09-03 Cephemverbindungen und verfahren zu ihrer herstellung.

Country Status (8)

Country Link
EP (1) EP0306863B1 (de)
JP (1) JP2595679B2 (de)
KR (1) KR970010070B1 (de)
AT (1) ATE97902T1 (de)
CA (1) CA1339739C (de)
DE (1) DE3885978T2 (de)
ES (1) ES2061579T3 (de)
GB (1) GB8721016D0 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA939336B (en) * 1992-12-21 1994-08-25 Fujisawa Pharmaceutical Co New cephem compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR78245B (de) * 1980-09-12 1984-09-26 Ciba Geigy Ag
DE3279470D1 (en) * 1981-04-03 1989-04-06 Fujisawa Pharmaceutical Co New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds
US4521413A (en) * 1981-09-14 1985-06-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds

Also Published As

Publication number Publication date
KR970010070B1 (ko) 1997-06-20
GB8721016D0 (en) 1987-10-14
JP2595679B2 (ja) 1997-04-02
DE3885978T2 (de) 1994-04-14
CA1339739C (en) 1998-03-17
EP0306863A2 (de) 1989-03-15
EP0306863A3 (en) 1989-11-08
DE3885978D1 (de) 1994-01-13
EP0306863B1 (de) 1993-12-01
KR890005123A (ko) 1989-05-11
JPH0193593A (ja) 1989-04-12
ES2061579T3 (es) 1994-12-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee