ATE48001T1 - Cephemverbindungen, verfahren zu ihrer herstellung und ihre pharmazeutischen praeparate. - Google Patents

Cephemverbindungen, verfahren zu ihrer herstellung und ihre pharmazeutischen praeparate.

Info

Publication number
ATE48001T1
ATE48001T1 AT85100326T AT85100326T ATE48001T1 AT E48001 T1 ATE48001 T1 AT E48001T1 AT 85100326 T AT85100326 T AT 85100326T AT 85100326 T AT85100326 T AT 85100326T AT E48001 T1 ATE48001 T1 AT E48001T1
Authority
AT
Austria
Prior art keywords
processes
production
cephem compounds
pharmaceutical preparations
compounds
Prior art date
Application number
AT85100326T
Other languages
English (en)
Inventor
Takao Takaya
Kazuo Sakane
Hideaki Yamanaka
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Application granted granted Critical
Publication of ATE48001T1 publication Critical patent/ATE48001T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT85100326T 1984-01-16 1985-01-15 Cephemverbindungen, verfahren zu ihrer herstellung und ihre pharmazeutischen praeparate. ATE48001T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848401093A GB8401093D0 (en) 1984-01-16 1984-01-16 Cephem compounds
EP85100326A EP0149487B1 (de) 1984-01-16 1985-01-15 Cephemverbindungen, Verfahren zu ihrer Herstellung und ihre pharmazeutischen Präparate

Publications (1)

Publication Number Publication Date
ATE48001T1 true ATE48001T1 (de) 1989-12-15

Family

ID=10555057

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85100326T ATE48001T1 (de) 1984-01-16 1985-01-15 Cephemverbindungen, verfahren zu ihrer herstellung und ihre pharmazeutischen praeparate.

Country Status (6)

Country Link
US (1) US4590186A (de)
EP (1) EP0149487B1 (de)
JP (1) JPH06789B2 (de)
AT (1) ATE48001T1 (de)
DE (1) DE3574256D1 (de)
GB (1) GB8401093D0 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH22107A (en) * 1984-06-07 1988-06-01 Takeda Chemical Industries Ltd 3-pyrazolo(1,5-a)pyrdinium cephem compounds
US4826834A (en) * 1985-09-27 1989-05-02 Takeda Chemical Industries, Ltd. Cephem compounds
AUPN955596A0 (en) * 1996-04-30 1996-05-23 Fujisawa Pharmaceutical Co., Ltd. New compound
TW526202B (en) 1998-11-27 2003-04-01 Shionogi & Amp Co Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity
US7294020B2 (en) * 2005-05-25 2007-11-13 Alcoa Fujikura Ltd. Canted coil spring power terminal and sequence connection system
US7229327B2 (en) * 2005-05-25 2007-06-12 Alcoa Fujikura Limited Canted coil spring power terminal and sequence connection system
CN102548999A (zh) * 2009-01-20 2012-07-04 山东轩竹医药科技有限公司 含有取代的含氮稠杂环的头孢菌素衍生物
HK1200096A1 (en) 2011-09-09 2015-07-31 Merck Sharp & Dohme Corp. Methods for treating intrapulmonary infections
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
US20140274994A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Stabilizing ceftolozane
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US20140274993A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane-tazobactam pharmaceutical compositions
US10376496B2 (en) 2013-09-09 2019-08-13 Merck, Sharp & Dohme Corp. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US8906898B1 (en) 2013-09-27 2014-12-09 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341775A (en) * 1978-09-11 1982-07-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
DE3279470D1 (en) * 1981-04-03 1989-04-06 Fujisawa Pharmaceutical Co New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
US4396620A (en) * 1981-09-08 1983-08-02 Eli Lilly And Company Cephalosporin quinolinium betaines
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
JPS6067484A (ja) * 1983-09-26 1985-04-17 Sankyo Co Ltd ピリダジニウムメチル置換基を有するセフアロスポリン誘導体
DE3336757A1 (de) * 1983-10-08 1985-04-25 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
US4590186A (en) 1986-05-20
EP0149487B1 (de) 1989-11-15
JPS60155183A (ja) 1985-08-15
JPH06789B2 (ja) 1994-01-05
EP0149487A3 (en) 1986-05-14
GB8401093D0 (en) 1984-02-15
DE3574256D1 (en) 1989-12-21
EP0149487A2 (de) 1985-07-24

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee