JPH06789B2 - 新規セフエム化合物およびその製造法 - Google Patents

新規セフエム化合物およびその製造法

Info

Publication number
JPH06789B2
JPH06789B2 JP60001355A JP135585A JPH06789B2 JP H06789 B2 JPH06789 B2 JP H06789B2 JP 60001355 A JP60001355 A JP 60001355A JP 135585 A JP135585 A JP 135585A JP H06789 B2 JPH06789 B2 JP H06789B2
Authority
JP
Japan
Prior art keywords
methyl
amino
formula
compound
cephem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP60001355A
Other languages
English (en)
Japanese (ja)
Other versions
JPS60155183A (ja
Inventor
隆男 高谷
和夫 坂根
秀昭 山中
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of JPS60155183A publication Critical patent/JPS60155183A/ja
Publication of JPH06789B2 publication Critical patent/JPH06789B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP60001355A 1984-01-16 1985-01-08 新規セフエム化合物およびその製造法 Expired - Lifetime JPH06789B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848401093A GB8401093D0 (en) 1984-01-16 1984-01-16 Cephem compounds
GB8401093 1984-01-16

Publications (2)

Publication Number Publication Date
JPS60155183A JPS60155183A (ja) 1985-08-15
JPH06789B2 true JPH06789B2 (ja) 1994-01-05

Family

ID=10555057

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60001355A Expired - Lifetime JPH06789B2 (ja) 1984-01-16 1985-01-08 新規セフエム化合物およびその製造法

Country Status (6)

Country Link
US (1) US4590186A (de)
EP (1) EP0149487B1 (de)
JP (1) JPH06789B2 (de)
AT (1) ATE48001T1 (de)
DE (1) DE3574256D1 (de)
GB (1) GB8401093D0 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH22107A (en) * 1984-06-07 1988-06-01 Takeda Chemical Industries Ltd 3-pyrazolo(1,5-a)pyrdinium cephem compounds
US4826834A (en) * 1985-09-27 1989-05-02 Takeda Chemical Industries, Ltd. Cephem compounds
AUPN955596A0 (en) * 1996-04-30 1996-05-23 Fujisawa Pharmaceutical Co., Ltd. New compound
TW526202B (en) 1998-11-27 2003-04-01 Shionogi & Amp Co Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity
US7294020B2 (en) * 2005-05-25 2007-11-13 Alcoa Fujikura Ltd. Canted coil spring power terminal and sequence connection system
US7229327B2 (en) * 2005-05-25 2007-06-12 Alcoa Fujikura Limited Canted coil spring power terminal and sequence connection system
WO2010083725A1 (zh) * 2009-01-20 2010-07-29 山东轩竹医药科技有限公司 含有取代的含氮稠杂环的头孢菌素衍生物
EP2862569A1 (de) 2011-09-09 2015-04-22 Cubist Pharmaceuticals, Inc. Verfahren zur Behandlung von intrapulmonalen Infektionen
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
KR102226197B1 (ko) 2013-03-15 2021-03-11 머크 샤프 앤드 돔 코포레이션 세프톨로잔 항균성 조성물
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US9320740B2 (en) 2013-03-15 2016-04-26 Merck Sharp & Dohme Corp. Ceftolozane-tazobactam pharmaceutical compositions
WO2015035376A2 (en) 2013-09-09 2015-03-12 Calixa Therapeutics, Inc. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341775A (en) * 1978-09-11 1982-07-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
EP0062321B1 (de) * 1981-04-03 1989-03-01 Fujisawa Pharmaceutical Co., Ltd. Cephalosporinderivate, Verfahren zu ihrer Herstellung, sie enthaltende pharmazeutische Präparate und ihre Ausgangsprodukte
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
US4396620A (en) * 1981-09-08 1983-08-02 Eli Lilly And Company Cephalosporin quinolinium betaines
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
JPS6067484A (ja) * 1983-09-26 1985-04-17 Sankyo Co Ltd ピリダジニウムメチル置換基を有するセフアロスポリン誘導体
DE3336757A1 (de) * 1983-10-08 1985-04-25 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
JPS60155183A (ja) 1985-08-15
US4590186A (en) 1986-05-20
ATE48001T1 (de) 1989-12-15
EP0149487A2 (de) 1985-07-24
EP0149487B1 (de) 1989-11-15
DE3574256D1 (en) 1989-12-21
GB8401093D0 (en) 1984-02-15
EP0149487A3 (en) 1986-05-14

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Legal Events

Date Code Title Description
EXPY Cancellation because of completion of term