DE3885978D1 - Cephemverbindungen und Verfahren zu ihrer Herstellung. - Google Patents

Cephemverbindungen und Verfahren zu ihrer Herstellung.

Info

Publication number
DE3885978D1
DE3885978D1 DE88114406T DE3885978T DE3885978D1 DE 3885978 D1 DE3885978 D1 DE 3885978D1 DE 88114406 T DE88114406 T DE 88114406T DE 3885978 T DE3885978 T DE 3885978T DE 3885978 D1 DE3885978 D1 DE 3885978D1
Authority
DE
Germany
Prior art keywords
alkyl
amino
protected
processes
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE88114406T
Other languages
English (en)
Other versions
DE3885978T2 (de
Inventor
Takao Takaya
Kazuo Sakane
Kenzi Miyai
Kohji Kawabata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of DE3885978D1 publication Critical patent/DE3885978D1/de
Application granted granted Critical
Publication of DE3885978T2 publication Critical patent/DE3885978T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE88114406T 1987-09-07 1988-09-03 Cephemverbindungen und Verfahren zu ihrer Herstellung. Expired - Fee Related DE3885978T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878721016A GB8721016D0 (en) 1987-09-07 1987-09-07 Cephem compounds

Publications (2)

Publication Number Publication Date
DE3885978D1 true DE3885978D1 (de) 1994-01-13
DE3885978T2 DE3885978T2 (de) 1994-04-14

Family

ID=10623397

Family Applications (1)

Application Number Title Priority Date Filing Date
DE88114406T Expired - Fee Related DE3885978T2 (de) 1987-09-07 1988-09-03 Cephemverbindungen und Verfahren zu ihrer Herstellung.

Country Status (8)

Country Link
EP (1) EP0306863B1 (de)
JP (1) JP2595679B2 (de)
KR (1) KR970010070B1 (de)
AT (1) ATE97902T1 (de)
CA (1) CA1339739C (de)
DE (1) DE3885978T2 (de)
ES (1) ES2061579T3 (de)
GB (1) GB8721016D0 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA939336B (en) * 1992-12-21 1994-08-25 Fujisawa Pharmaceutical Co New cephem compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR78245B (de) * 1980-09-12 1984-09-26 Ciba Geigy Ag
EP0062321B1 (de) * 1981-04-03 1989-03-01 Fujisawa Pharmaceutical Co., Ltd. Cephalosporinderivate, Verfahren zu ihrer Herstellung, sie enthaltende pharmazeutische Präparate und ihre Ausgangsprodukte
US4521413A (en) * 1981-09-14 1985-06-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds

Also Published As

Publication number Publication date
GB8721016D0 (en) 1987-10-14
DE3885978T2 (de) 1994-04-14
ATE97902T1 (de) 1993-12-15
JPH0193593A (ja) 1989-04-12
ES2061579T3 (es) 1994-12-16
EP0306863A2 (de) 1989-03-15
KR970010070B1 (ko) 1997-06-20
KR890005123A (ko) 1989-05-11
CA1339739C (en) 1998-03-17
EP0306863B1 (de) 1993-12-01
EP0306863A3 (en) 1989-11-08
JP2595679B2 (ja) 1997-04-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee