AU7998087A - 1-hydroxyalkylxanthines, processes for their preparation and medicaments containing them - Google Patents

1-hydroxyalkylxanthines, processes for their preparation and medicaments containing them

Info

Publication number
AU7998087A
AU7998087A AU79980/87A AU7998087A AU7998087A AU 7998087 A AU7998087 A AU 7998087A AU 79980/87 A AU79980/87 A AU 79980/87A AU 7998087 A AU7998087 A AU 7998087A AU 7998087 A AU7998087 A AU 7998087A
Authority
AU
Australia
Prior art keywords
hydroxyalkylxanthines
processes
preparation
medicaments containing
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU79980/87A
Other versions
AU604767B2 (en
Inventor
Rene Fumeaux
Georges Philippossian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe des Produits Nestle SA
Original Assignee
Societe des Produits Nestle SA
Nestle SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe des Produits Nestle SA, Nestle SA filed Critical Societe des Produits Nestle SA
Publication of AU7998087A publication Critical patent/AU7998087A/en
Application granted granted Critical
Publication of AU604767B2 publication Critical patent/AU604767B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Compound of formula: <IMAGE> or a physiologically acceptable salt of this compound, in which formula R1 is a C2-C5 omega -hydroxy-n-alkyl or C3-C5 ( omega -1)-hydroxy-n-alkyl, R3 is a C1-C4 alkyl group, R8 is H, methyl or ethyl, and the sum of the carbon atoms in R1 and R3 is between 4 and 9. Pharmaceutical composition containing this compound.
AU79980/87A 1986-10-27 1987-10-21 1-hydroxyalkylxanthines, processes for their preparation and medicaments containing them Ceased AU604767B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH4253/86 1986-10-27
CH4253/86A CH670090A5 (en) 1986-10-27 1986-10-27

Publications (2)

Publication Number Publication Date
AU7998087A true AU7998087A (en) 1988-04-28
AU604767B2 AU604767B2 (en) 1991-01-03

Family

ID=4272668

Family Applications (1)

Application Number Title Priority Date Filing Date
AU79980/87A Ceased AU604767B2 (en) 1986-10-27 1987-10-21 1-hydroxyalkylxanthines, processes for their preparation and medicaments containing them

Country Status (13)

Country Link
EP (1) EP0269841B1 (en)
JP (1) JP2527769B2 (en)
KR (1) KR930010559B1 (en)
AT (1) ATE82289T1 (en)
AU (1) AU604767B2 (en)
CA (1) CA1296001C (en)
CH (1) CH670090A5 (en)
DE (1) DE3782619T2 (en)
DK (1) DK169336B1 (en)
ES (1) ES2043631T3 (en)
GR (1) GR3006223T3 (en)
IL (1) IL84266A (en)
ZA (1) ZA877851B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0570831A2 (en) * 1992-05-20 1993-11-24 Hoechst Aktiengesellschaft Use of Xanthinderivatives for treatment of cerebral nerve dammages after disruption of the blood circulation
DE4316576A1 (en) * 1993-05-18 1994-11-24 Boehringer Ingelheim Kg Improved process for the preparation of 1,3-dipropyl-8- (3-oxocyclopentyl) xanthine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2517410A (en) * 1947-08-15 1950-08-01 Searle & Co Hydroxy alkyl xanthines and the production thereof
FR1211333A (en) * 1955-10-19 1960-03-15 Boehringer Sohn Ingelheim Improvements in processes for manufacturing oxyalkylxanthines
US4567183A (en) * 1983-03-11 1986-01-28 Analgesic Associates Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same
US4558051A (en) * 1983-10-11 1985-12-10 Richardson-Vicks, Inc. Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same

Also Published As

Publication number Publication date
KR930010559B1 (en) 1993-10-28
JPS63122683A (en) 1988-05-26
GR3006223T3 (en) 1993-06-21
AU604767B2 (en) 1991-01-03
CA1296001C (en) 1992-02-18
CH670090A5 (en) 1989-05-12
IL84266A (en) 1992-02-16
DK551487A (en) 1988-04-28
EP0269841A1 (en) 1988-06-08
ZA877851B (en) 1988-04-22
IL84266A0 (en) 1988-03-31
DE3782619D1 (en) 1992-12-17
DE3782619T2 (en) 1993-04-22
DK551487D0 (en) 1987-10-21
KR880005131A (en) 1988-06-28
EP0269841B1 (en) 1992-11-11
ES2043631T3 (en) 1994-01-01
JP2527769B2 (en) 1996-08-28
DK169336B1 (en) 1994-10-10
ATE82289T1 (en) 1992-11-15

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