ZA877851B - 1-hydroxyalkylxanthines,processes for their preparation and medicaments containing them - Google Patents

1-hydroxyalkylxanthines,processes for their preparation and medicaments containing them

Info

Publication number
ZA877851B
ZA877851B ZA877851A ZA877851A ZA877851B ZA 877851 B ZA877851 B ZA 877851B ZA 877851 A ZA877851 A ZA 877851A ZA 877851 A ZA877851 A ZA 877851A ZA 877851 B ZA877851 B ZA 877851B
Authority
ZA
South Africa
Prior art keywords
hydroxyalkylxanthines
processes
preparation
medicaments containing
compound
Prior art date
Application number
ZA877851A
Inventor
Fumeaux Rene
Philippossian Georges
Original Assignee
Societe Des Produits Nestle S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe Des Produits Nestle S.A. filed Critical Societe Des Produits Nestle S.A.
Publication of ZA877851B publication Critical patent/ZA877851B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Compound of formula: <IMAGE> or a physiologically acceptable salt of this compound, in which formula R1 is a C2-C5 omega -hydroxy-n-alkyl or C3-C5 ( omega -1)-hydroxy-n-alkyl, R3 is a C1-C4 alkyl group, R8 is H, methyl or ethyl, and the sum of the carbon atoms in R1 and R3 is between 4 and 9. Pharmaceutical composition containing this compound.
ZA877851A 1986-10-27 1987-10-19 1-hydroxyalkylxanthines,processes for their preparation and medicaments containing them ZA877851B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH4253/86A CH670090A5 (en) 1986-10-27 1986-10-27

Publications (1)

Publication Number Publication Date
ZA877851B true ZA877851B (en) 1988-04-22

Family

ID=4272668

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA877851A ZA877851B (en) 1986-10-27 1987-10-19 1-hydroxyalkylxanthines,processes for their preparation and medicaments containing them

Country Status (13)

Country Link
EP (1) EP0269841B1 (en)
JP (1) JP2527769B2 (en)
KR (1) KR930010559B1 (en)
AT (1) ATE82289T1 (en)
AU (1) AU604767B2 (en)
CA (1) CA1296001C (en)
CH (1) CH670090A5 (en)
DE (1) DE3782619T2 (en)
DK (1) DK169336B1 (en)
ES (1) ES2043631T3 (en)
GR (1) GR3006223T3 (en)
IL (1) IL84266A (en)
ZA (1) ZA877851B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0570831A2 (en) * 1992-05-20 1993-11-24 Hoechst Aktiengesellschaft Use of Xanthinderivatives for treatment of cerebral nerve dammages after disruption of the blood circulation
DE4316576A1 (en) * 1993-05-18 1994-11-24 Boehringer Ingelheim Kg Improved process for the preparation of 1,3-dipropyl-8- (3-oxocyclopentyl) xanthine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2517410A (en) * 1947-08-15 1950-08-01 Searle & Co Hydroxy alkyl xanthines and the production thereof
FR1211333A (en) * 1955-10-19 1960-03-15 Boehringer Sohn Ingelheim Improvements in processes for manufacturing oxyalkylxanthines
US4567183A (en) * 1983-03-11 1986-01-28 Analgesic Associates Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same
US4558051A (en) * 1983-10-11 1985-12-10 Richardson-Vicks, Inc. Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same

Also Published As

Publication number Publication date
IL84266A (en) 1992-02-16
EP0269841B1 (en) 1992-11-11
ES2043631T3 (en) 1994-01-01
GR3006223T3 (en) 1993-06-21
IL84266A0 (en) 1988-03-31
KR930010559B1 (en) 1993-10-28
DK169336B1 (en) 1994-10-10
EP0269841A1 (en) 1988-06-08
AU7998087A (en) 1988-04-28
CH670090A5 (en) 1989-05-12
DE3782619D1 (en) 1992-12-17
ATE82289T1 (en) 1992-11-15
DK551487D0 (en) 1987-10-21
DE3782619T2 (en) 1993-04-22
KR880005131A (en) 1988-06-28
DK551487A (en) 1988-04-28
AU604767B2 (en) 1991-01-03
CA1296001C (en) 1992-02-18
JPS63122683A (en) 1988-05-26
JP2527769B2 (en) 1996-08-28

Similar Documents

Publication Publication Date Title
DE3372707D1 (en) Spiro-(4,(3+n))-2-aza-alkan-3-carboxylic-acid derivatives, process for their preparation,agents containing them and their use
AU7503087A (en) Amide derivatives
GR3022113T3 (en) Pyrazolopyridine compounds and processes for preparation thereof
EP0228845A3 (en) N-containing heterocyclic compounds, processes for the preparation thereof and composition comprising the same
KR0133073B1 (en) Antiviral tetrahydroimidazo(1,4)benzodiazepin-2-ones
ZA872683B (en) 1,5-benzothiazepine derivatives,their preparation and compositions containing them
IL84266A0 (en) 1-hydroxyalkylxanthines,processes for their preparation and medicaments containing them
GR3007219T3 (en)
ZA935277B (en) Aminoalkylchromones processes for the preparation thereof and pharmaceutical compositions containing them
AU6089686A (en) 1-alkyl ergolinylthiourea derivatives, process for the preparation thereof, as well as their use as medicinal agents
DE3885978D1 (en) Cephem compounds and processes for their preparation.