DK1994937T3 - Forebyggelse og behandling af amyloidogen sygdom - Google Patents

Forebyggelse og behandling af amyloidogen sygdom

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Publication number
DK1994937T3
DK1994937T3 DK08011409.3T DK08011409T DK1994937T3 DK 1994937 T3 DK1994937 T3 DK 1994937T3 DK 08011409 T DK08011409 T DK 08011409T DK 1994937 T3 DK1994937 T3 DK 1994937T3
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DK
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Prior art keywords
prevention
treatment
amyloidogenic disease
amyloidogenic
disease
Prior art date
Application number
DK08011409.3T
Other languages
English (en)
Inventor
Dale B Schenk
Original Assignee
Janssen Alzheimer Immunotherap
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26748211&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1994937(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Alzheimer Immunotherap filed Critical Janssen Alzheimer Immunotherap
Application granted granted Critical
Publication of DK1994937T3 publication Critical patent/DK1994937T3/da

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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/739Lipopolysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
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    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
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    • A61K47/646Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
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    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
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    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
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    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6037Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK08011409.3T 1997-12-02 1998-11-30 Forebyggelse og behandling af amyloidogen sygdom DK1994937T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6774097P 1997-12-02 1997-12-02
US8097098P 1998-04-07 1998-04-07
EP98961833A EP1033996B1 (en) 1997-12-02 1998-11-30 Prevention and treatment of amyloidogenic disease

Publications (1)

Publication Number Publication Date
DK1994937T3 true DK1994937T3 (da) 2011-02-07

Family

ID=26748211

Family Applications (4)

Application Number Title Priority Date Filing Date
DK98961833T DK1033996T3 (da) 1997-12-02 1998-11-30 Forebyggelse og behandling af amyloidogen sygdom
DK08011409.3T DK1994937T3 (da) 1997-12-02 1998-11-30 Forebyggelse og behandling af amyloidogen sygdom
DK10182575.0T DK2305282T3 (da) 1997-12-02 1998-11-30 Forebyggelse og behandling af amyloidogen sygdom
DK06075479T DK1679080T3 (da) 1997-12-02 1998-11-30 Forebyggelse og behandling af amyloidogen sygdom

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK98961833T DK1033996T3 (da) 1997-12-02 1998-11-30 Forebyggelse og behandling af amyloidogen sygdom

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK10182575.0T DK2305282T3 (da) 1997-12-02 1998-11-30 Forebyggelse og behandling af amyloidogen sygdom
DK06075479T DK1679080T3 (da) 1997-12-02 1998-11-30 Forebyggelse og behandling af amyloidogen sygdom

Country Status (38)

Country Link
US (26) US20040171815A1 (da)
EP (5) EP1033996B1 (da)
JP (4) JP4677094B2 (da)
KR (3) KR20120135915A (da)
CN (1) CN100374151C (da)
AR (1) AR020050A1 (da)
AT (4) ATE493149T1 (da)
AU (1) AU1706199A (da)
BG (1) BG104562A (da)
BR (1) BR9815357A (da)
CA (1) CA2312920C (da)
CO (1) CO4980846A1 (da)
CY (3) CY1108331T1 (da)
CZ (1) CZ303137B6 (da)
DE (7) DE69839647D1 (da)
DK (4) DK1033996T3 (da)
EA (3) EA200000608A1 (da)
EE (1) EE05377B1 (da)
ES (4) ES2263408T3 (da)
GE (2) GEP20043319B (da)
HK (2) HK1095265A1 (da)
HR (2) HRP20000443B1 (da)
HU (2) HU228493B1 (da)
ID (1) ID25504A (da)
IL (5) IL136252A0 (da)
IS (1) IS5500A (da)
MY (1) MY134906A (da)
NO (3) NO328865B1 (da)
NZ (1) NZ504569A (da)
PE (1) PE20001383A1 (da)
PL (2) PL202706B1 (da)
PT (4) PT1994937E (da)
SA (1) SA99191269B1 (da)
SG (1) SG111083A1 (da)
SI (4) SI2305282T1 (da)
TR (1) TR200001608T2 (da)
TW (1) TWI239847B (da)
WO (1) WO1999027944A1 (da)

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US20080050367A1 (en) 1998-04-07 2008-02-28 Guriq Basi Humanized antibodies that recognize beta amyloid peptide
US6787523B1 (en) 1997-12-02 2004-09-07 Neuralab Limited Prevention and treatment of amyloidogenic disease
US7179892B2 (en) * 2000-12-06 2007-02-20 Neuralab Limited Humanized antibodies that recognize beta amyloid peptide
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US6761888B1 (en) * 2000-05-26 2004-07-13 Neuralab Limited Passive immunization treatment of Alzheimer's disease
US6743427B1 (en) 1997-12-02 2004-06-01 Neuralab Limited Prevention and treatment of amyloidogenic disease
US7790856B2 (en) 1998-04-07 2010-09-07 Janssen Alzheimer Immunotherapy Humanized antibodies that recognize beta amyloid peptide
US20050059802A1 (en) * 1998-04-07 2005-03-17 Neuralab Ltd Prevention and treatment of amyloidogenic disease
US20030147882A1 (en) 1998-05-21 2003-08-07 Alan Solomon Methods for amyloid removal using anti-amyloid antibodies
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WO2000069456A2 (en) 1999-05-13 2000-11-23 American Cyanamid Company Adjuvant combination formulations
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PE20010212A1 (es) * 1999-06-01 2001-02-22 Neuralab Ltd Composiciones del peptido a-beta y procesos para producir las mismas
DK1409654T3 (da) 1999-06-16 2008-12-08 Boston Biomedical Res Inst Immunologisk styring af beta-amyloid-niveauer in vivo
DE60044057D1 (de) * 1999-09-03 2010-05-06 Univ Ramot Verbindungen, zusammensetzungen und verfahren zur behandlung oder vorsorge von alzheimer erkrankung
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US20020094335A1 (en) * 1999-11-29 2002-07-18 Robert Chalifour Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
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EP1752472A3 (en) * 1999-12-08 2007-04-25 Intellect Neurosciences, Inc. Chimeric amyloid beta peptides
CA2393763A1 (en) * 1999-12-08 2001-06-14 Mindset Biopharmaceuticals (Usa), Inc. Chimeric peptides as immunogens, antibodies thereto, and methods for immunization using chimeric peptides or antibodies
CZ20022748A3 (cs) * 2000-02-21 2004-03-17 Pharmexa A/S Nová metoda regulace obsahu amyloidu
EE200200444A (et) * 2000-02-21 2003-12-15 Pharmexa A/S Meetod autoloogse beeta-amüloidvaigu in vivo mahasurumiseks, amüloidogeense polüpeptiidi analoog, seda kodeeriv nukleiinhappefragment ning kasutamineimmunogeense kompositsiooni valmistamiseks
SK288711B6 (sk) * 2000-02-24 2019-11-05 Univ Washington Humanizovaná protilátka, jej fragment a ich použitie, polynukleová kyselina, expresný vektor, bunka a farmaceutický prostriedok
CA2404237C (en) * 2000-04-05 2010-01-26 University Of Tennessee Research Corporation Methods of investigating, diagnosing, and treating amyloidosis
DE60108111T2 (de) * 2000-05-22 2005-12-08 New York University Synthetische immunogene jedoch nicht amyloidogene peptide, die homolog zu amyloid beta sind und deren verwendung zur induktion einer immunantwort gegen amyloid beta und amyloidaggregate
JP2003516929A (ja) * 2000-06-01 2003-05-20 ニユーララブ・リミテツド アミロイド形成性疾患の予防および治療
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US20040171815A1 (en) 2004-09-02
US20050048049A1 (en) 2005-03-03
CN1281366A (zh) 2001-01-24
SI1994937T1 (sl) 2011-04-29
US20050196399A1 (en) 2005-09-08
GEP20053715B (en) 2005-12-26
JP4677333B2 (ja) 2011-04-27
US20050031629A1 (en) 2005-02-10
EE05377B1 (et) 2011-02-15
EP1690547B1 (en) 2009-07-08
SI1033996T1 (sl) 2009-02-28
US20050163788A1 (en) 2005-07-28
JP4677094B2 (ja) 2011-04-27
US20050249727A1 (en) 2005-11-10
NO332813B1 (no) 2013-01-21
SI2305282T1 (sl) 2013-10-30
ES2428740T3 (es) 2013-11-11
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US20080096818A1 (en) 2008-04-24
US20140227274A1 (en) 2014-08-14
US8642044B2 (en) 2014-02-04
CN100374151C (zh) 2008-03-12
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EP1679080A2 (en) 2006-07-12
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US6808712B2 (en) 2004-10-26
US6946135B2 (en) 2005-09-20
DK2305282T3 (da) 2013-10-07
DK1679080T3 (da) 2009-09-28
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ATE435659T1 (de) 2009-07-15
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US20050142132A1 (en) 2005-06-30
NO328865B1 (no) 2010-06-07
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ID25504A (id) 2000-10-05
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ES2310017T3 (es) 2008-12-16
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EP1994937A3 (en) 2008-12-24
IL193245A0 (en) 2009-09-22
IL205298A0 (en) 2011-07-31
HUP0100627A3 (en) 2006-03-28
NO20100061L (no) 2000-07-31
EE200000379A (et) 2001-04-16
US20090191231A1 (en) 2009-07-30
KR20090078366A (ko) 2009-07-17
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US20050191292A1 (en) 2005-09-01
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US8535673B2 (en) 2013-09-17
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US7014855B2 (en) 2006-03-21
EP1994937A2 (en) 2008-11-26
KR20120135915A (ko) 2012-12-17
GEP20043319B (en) 2004-05-10
CA2312920A1 (en) 1999-06-10
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NO20092874L (no) 2000-07-31
DE69842082D1 (de) 2011-02-10
JP2006131639A (ja) 2006-05-25
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US20060034858A1 (en) 2006-02-16
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US20080227719A1 (en) 2008-09-18
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US20060029611A1 (en) 2006-02-09
PT1994937E (pt) 2011-02-22
BR9815357A (pt) 2000-10-24
US20120276116A1 (en) 2012-11-01
IL191904A (en) 2014-05-28
HU228493B1 (en) 2013-03-28
AU1706199A (en) 1999-06-16
US8034348B2 (en) 2011-10-11
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CY1109368T1 (el) 2014-07-02
CA2312920C (en) 2016-07-12
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US20050191314A1 (en) 2005-09-01
WO1999027944A1 (en) 1999-06-10
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KR100936419B1 (ko) 2010-01-12
EP1994937B1 (en) 2010-12-29
NO20002784D0 (no) 2000-05-31
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US20050037026A1 (en) 2005-02-17
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