EP0726906A4 - Synthesizing and screening molecular diversity - Google Patents

Synthesizing and screening molecular diversity

Info

Publication number
EP0726906A4
EP0726906A4 EP95902404A EP95902404A EP0726906A4 EP 0726906 A4 EP0726906 A4 EP 0726906A4 EP 95902404 A EP95902404 A EP 95902404A EP 95902404 A EP95902404 A EP 95902404A EP 0726906 A4 EP0726906 A4 EP 0726906A4
Authority
EP
European Patent Office
Prior art keywords
synthesizing
molecular diversity
screening molecular
screening
diversity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95902404A
Other languages
German (de)
French (fr)
Other versions
EP0726906A1 (en
Inventor
Jeffrey H Sugarman
Richard P Rava
Haim Kedar
William J Dower
Ronald W Barrett
Mark A Gallop
Michael C Needels
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Affymetrix Inc
Original Assignee
Affymax Technologies NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/146,886 external-priority patent/US5639603A/en
Priority claimed from US08/149,675 external-priority patent/US5503805A/en
Application filed by Affymax Technologies NV filed Critical Affymax Technologies NV
Publication of EP0726906A1 publication Critical patent/EP0726906A1/en
Publication of EP0726906A4 publication Critical patent/EP0726906A4/en
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
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    • C12Q1/6813—Hybridisation assays
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US08/146,886 US5639603A (en) 1991-09-18 1993-11-02 Synthesizing and screening molecular diversity
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AU1128095A (en) 1995-05-23
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AU703472B2 (en) 1999-03-25
JPH09508353A (en) 1997-08-26
GB2298863A (en) 1996-09-18
GB2298863B (en) 1998-03-11
WO1995012608A1 (en) 1995-05-11
EP0726906A1 (en) 1996-08-21
BR9407947A (en) 1996-11-26
CN1134156A (en) 1996-10-23

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