GB9609254D0 - Synthesizing and screening molecular diversity - Google Patents

Synthesizing and screening molecular diversity

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Publication number
GB9609254D0
GB9609254D0 GBGB9609254.9A GB9609254A GB9609254D0 GB 9609254 D0 GB9609254 D0 GB 9609254D0 GB 9609254 A GB9609254 A GB 9609254A GB 9609254 D0 GB9609254 D0 GB 9609254D0
Authority
GB
United Kingdom
Prior art keywords
synthesizing
molecular diversity
screening molecular
screening
diversity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GBGB9609254.9A
Other versions
GB2298863A (en
GB2298863B (en
Inventor
Jeffrey H Sugarman
Richard P Rava
Haim Kedar
William J Dower
Ronald W Barrett
Mark A Gallop
Michael C Needels
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Affymax Technologies NV
Original Assignee
Affymax Technologies NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/149,675 external-priority patent/US5503805A/en
Priority claimed from US08/146,886 external-priority patent/US5639603A/en
Application filed by Affymax Technologies NV filed Critical Affymax Technologies NV
Publication of GB9609254D0 publication Critical patent/GB9609254D0/en
Publication of GB2298863A publication Critical patent/GB2298863A/en
Application granted granted Critical
Publication of GB2298863B publication Critical patent/GB2298863B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047Simultaneous synthesis of different peptide species; Peptide libraries
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6811Selection methods for production or design of target specific oligonucleotides or binding molecules
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
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    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
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    • C40COMBINATORIAL TECHNOLOGY
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    • C40B60/14Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

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  • Chemical & Material Sciences (AREA)
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  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
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  • Wood Science & Technology (AREA)
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  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
GB9609254A 1993-11-02 1994-11-02 Apparatus and process for the synthesis of diverse compounds especially for generating and screening compound libraries Expired - Fee Related GB2298863B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/149,675 US5503805A (en) 1993-11-02 1993-11-02 Apparatus and method for parallel coupling reactions
US08/146,886 US5639603A (en) 1991-09-18 1993-11-02 Synthesizing and screening molecular diversity
PCT/US1994/012347 WO1995012608A1 (en) 1993-11-02 1994-11-02 Synthesizing and screening molecular diversity

Publications (3)

Publication Number Publication Date
GB9609254D0 true GB9609254D0 (en) 1996-07-03
GB2298863A GB2298863A (en) 1996-09-18
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AU703472B2 (en) 1999-03-25
AU1128095A (en) 1995-05-23
CN1134156A (en) 1996-10-23
BR9407947A (en) 1996-11-26
GB2298863A (en) 1996-09-18
NZ276860A (en) 1997-09-22
EP0726906A4 (en) 1998-10-07
JPH09508353A (en) 1997-08-26
GB2298863B (en) 1998-03-11
EP0726906A1 (en) 1996-08-21
CA2175587A1 (en) 1995-05-11
WO1995012608A1 (en) 1995-05-11

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