CO4980846A1 - Una composicion farmaceutica utilizada en un metodo para la prevencion y tratamiento de la enfermedad amiloidogenica - Google Patents

Una composicion farmaceutica utilizada en un metodo para la prevencion y tratamiento de la enfermedad amiloidogenica

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Publication number
CO4980846A1
CO4980846A1 CO98071271A CO98071271A CO4980846A1 CO 4980846 A1 CO4980846 A1 CO 4980846A1 CO 98071271 A CO98071271 A CO 98071271A CO 98071271 A CO98071271 A CO 98071271A CO 4980846 A1 CO4980846 A1 CO 4980846A1
Authority
CO
Colombia
Prior art keywords
pharmaceutical composition
inducing
patient
effective
response against
Prior art date
Application number
CO98071271A
Other languages
English (en)
Inventor
Dale B Schenk
Original Assignee
Athena Neurosciences Inc
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26748211&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO4980846(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Athena Neurosciences Inc filed Critical Athena Neurosciences Inc
Publication of CO4980846A1 publication Critical patent/CO4980846A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/739—Lipopolysaccharides
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
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    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
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    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
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    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
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    • A—HUMAN NECESSITIES
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    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
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    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
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  • Biomedical Technology (AREA)
  • Neurology (AREA)
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  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Toxicology (AREA)
  • Microbiology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Una composición farmacéutica que comprende un agente que eseficaz para inducir una respuesta inmunogénica contra Aß en un paciente, y un coadyuvante farmacéuticamente aceptable. Un método para evitar o tratar una enfermedad caracterizada por un depósito amiloide en un paciente que comprende: administrar un agente eficaz para inducir una respuesta inmunitaria contra un componente péptido de un depósito amiloide en el paciente. 4Una composición farmacéutica que comprende un agente que es eficaz para inducir una respuesta inmunogénica contra Aß en un paciente, con la condición de que la composición esté libre del coadyuvante completo de Freund. Una composición que comprende un vector viral que codifica aß o un fragmento del mismo que es eficaz para inducir una respuesta inmunitaria contra Aß y un portador farmacéuticamente aceptable.
CO98071271A 1997-12-02 1998-12-01 Una composicion farmaceutica utilizada en un metodo para la prevencion y tratamiento de la enfermedad amiloidogenica CO4980846A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6774097P 1997-12-02 1997-12-02
US8097098P 1998-04-07 1998-04-07

Publications (1)

Publication Number Publication Date
CO4980846A1 true CO4980846A1 (es) 2000-11-27

Family

ID=26748211

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Application Number Title Priority Date Filing Date
CO98071271A CO4980846A1 (es) 1997-12-02 1998-12-01 Una composicion farmaceutica utilizada en un metodo para la prevencion y tratamiento de la enfermedad amiloidogenica

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US (26) US20040171815A1 (es)
EP (5) EP1033996B1 (es)
JP (4) JP4677094B2 (es)
KR (3) KR101248711B1 (es)
CN (1) CN100374151C (es)
AR (1) AR020050A1 (es)
AT (4) ATE433760T1 (es)
AU (1) AU1706199A (es)
BG (1) BG104562A (es)
BR (1) BR9815357A (es)
CA (1) CA2312920C (es)
CO (1) CO4980846A1 (es)
CY (3) CY1108331T1 (es)
CZ (1) CZ303137B6 (es)
DE (7) DE69840969D1 (es)
DK (4) DK1679080T3 (es)
EA (3) EA007218B1 (es)
EE (1) EE05377B1 (es)
ES (4) ES2262460T1 (es)
GE (2) GEP20053715B (es)
HK (2) HK1095265A1 (es)
HR (2) HRP20000443B1 (es)
HU (2) HU228493B1 (es)
ID (1) ID25504A (es)
IL (5) IL136252A0 (es)
IS (1) IS5500A (es)
MY (1) MY134906A (es)
NO (3) NO328865B1 (es)
NZ (1) NZ504569A (es)
PE (1) PE20001383A1 (es)
PL (2) PL202706B1 (es)
PT (4) PT1033996E (es)
SA (1) SA99191269B1 (es)
SG (1) SG111083A1 (es)
SI (4) SI1033996T1 (es)
TR (1) TR200001608T2 (es)
TW (1) TWI239847B (es)
WO (1) WO1999027944A1 (es)

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