ATE305039T1 - Auf chromosom 1 lokalisiertes gen dessen genprodukt mit der alzheimerschen krankheit assoziiert ist. - Google Patents
Auf chromosom 1 lokalisiertes gen dessen genprodukt mit der alzheimerschen krankheit assoziiert ist.Info
- Publication number
- ATE305039T1 ATE305039T1 AT96926062T AT96926062T ATE305039T1 AT E305039 T1 ATE305039 T1 AT E305039T1 AT 96926062 T AT96926062 T AT 96926062T AT 96926062 T AT96926062 T AT 96926062T AT E305039 T1 ATE305039 T1 AT E305039T1
- Authority
- AT
- Austria
- Prior art keywords
- disease
- alzheimer
- chromosome
- gene localized
- genes product
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 208000024827 Alzheimer disease Diseases 0.000 title abstract 2
- 210000000349 chromosome Anatomy 0.000 title 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0306—Animal model for genetic diseases
- A01K2267/0312—Animal model for Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US95695P | 1995-07-07 | 1995-07-07 | |
US167595P | 1995-07-28 | 1995-07-28 | |
US217495P | 1995-08-11 | 1995-08-11 | |
US232895P | 1995-08-14 | 1995-08-14 | |
PCT/US1996/011386 WO1997003192A2 (en) | 1995-07-07 | 1996-07-05 | Chromosome 1 gene and gene products related to alzheimer's disease |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE305039T1 true ATE305039T1 (de) | 2005-10-15 |
Family
ID=27485043
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96926062T ATE305039T1 (de) | 1995-07-07 | 1996-07-05 | Auf chromosom 1 lokalisiertes gen dessen genprodukt mit der alzheimerschen krankheit assoziiert ist. |
Country Status (7)
Country | Link |
---|---|
US (2) | US6468791B1 (de) |
EP (2) | EP1637600A1 (de) |
JP (3) | JP4073955B2 (de) |
AT (1) | ATE305039T1 (de) |
CA (1) | CA2226255A1 (de) |
DE (1) | DE69635207T2 (de) |
WO (1) | WO1997003192A2 (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6210919B1 (en) | 1995-04-28 | 2001-04-03 | Hsc Research And Development Limited Partnership | Genetic sequences and proteins related to alzheimer's disease |
JP5379119B2 (ja) * | 1995-04-28 | 2013-12-25 | エイチエスシー リサーチ アンド ディベロップメント リミテッド | アルツハイマー病に関連する遺伝子配列およびタンパク質、ならびにその使用 |
US5986054A (en) * | 1995-04-28 | 1999-11-16 | The Hospital For Sick Children, Hsc Research And Development Limited Partnership | Genetic sequences and proteins related to alzheimer's disease |
US6531586B1 (en) | 1995-04-28 | 2003-03-11 | The Hospital For Sick Children | Genetic sequences related to Alzheimer's Disease |
WO1997007213A2 (en) * | 1995-08-16 | 1997-02-27 | President And Fellows Of Harvard College | Assay for identifying genes causing chromosome non-disjunction |
WO1997027296A1 (en) * | 1996-01-26 | 1997-07-31 | Hsc Research And Development Limited Partnership | Nucleic acids and proteins related to alzheimer's disease, and uses therefor |
ES2128265B1 (es) * | 1997-06-04 | 2000-03-01 | Euroespes S A | Kit genetico para la caracterizacion molecular de la enfermedad de alzheimer. |
TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
US7964192B1 (en) | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
US20080050367A1 (en) | 1998-04-07 | 2008-02-28 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
US7790856B2 (en) | 1998-04-07 | 2010-09-07 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize beta amyloid peptide |
AU1957299A (en) | 1998-01-09 | 1999-07-26 | Governing Council Of The University Of Toronto, The | Presenilin protein interactions |
US7700751B2 (en) | 2000-12-06 | 2010-04-20 | Janssen Alzheimer Immunotherapy | Humanized antibodies that recognize β-amyloid peptide |
JP2003018991A (ja) * | 2001-06-27 | 2003-01-21 | Japan Science & Technology Corp | プレセニリン−2遺伝子エキソン5欠損型スプライシング異常の生成に関与する核酸 |
MY139983A (en) | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
TWI306458B (en) | 2003-05-30 | 2009-02-21 | Elan Pharma Int Ltd | Humanized antibodies that recognize beta amyloid peptide |
AR052051A1 (es) | 2004-12-15 | 2007-02-28 | Neuralab Ltd | Anticuerpos ab humanizados usados en mejorar la cognicion |
US8784810B2 (en) | 2006-04-18 | 2014-07-22 | Janssen Alzheimer Immunotherapy | Treatment of amyloidogenic diseases |
WO2009017467A1 (en) | 2007-07-27 | 2009-02-05 | Elan Pharma International Limited | Treatment of amyloidogenic diseases |
CN101467018B (zh) * | 2006-06-12 | 2011-11-16 | 卡泊尔投资公司 | 接管检验设备及方法 |
US8003097B2 (en) | 2007-04-18 | 2011-08-23 | Janssen Alzheimer Immunotherapy | Treatment of cerebral amyloid angiopathy |
JO3076B1 (ar) | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | نظم العلاج المناعي المعتمد على حالة apoe |
US9067981B1 (en) | 2008-10-30 | 2015-06-30 | Janssen Sciences Ireland Uc | Hybrid amyloid-beta antibodies |
CN104011192B (zh) * | 2011-12-20 | 2017-08-25 | 荷兰联合利华有限公司 | 包含去污聚合物的各向同性液体洗涤剂 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6210919B1 (en) * | 1995-04-28 | 2001-04-03 | Hsc Research And Development Limited Partnership | Genetic sequences and proteins related to alzheimer's disease |
US5986054A (en) * | 1995-04-28 | 1999-11-16 | The Hospital For Sick Children, Hsc Research And Development Limited Partnership | Genetic sequences and proteins related to alzheimer's disease |
-
1996
- 1996-07-05 EP EP05015005A patent/EP1637600A1/de not_active Withdrawn
- 1996-07-05 CA CA002226255A patent/CA2226255A1/en not_active Abandoned
- 1996-07-05 DE DE69635207T patent/DE69635207T2/de not_active Expired - Lifetime
- 1996-07-05 WO PCT/US1996/011386 patent/WO1997003192A2/en active IP Right Grant
- 1996-07-05 JP JP50592597A patent/JP4073955B2/ja not_active Expired - Fee Related
- 1996-07-05 AT AT96926062T patent/ATE305039T1/de not_active IP Right Cessation
- 1996-07-05 EP EP96926062A patent/EP0846171B1/de not_active Expired - Lifetime
-
1999
- 1999-08-16 US US09/375,318 patent/US6468791B1/en not_active Expired - Fee Related
-
2002
- 2002-06-24 US US10/180,781 patent/US20030180880A1/en not_active Abandoned
-
2007
- 2007-08-08 JP JP2007206900A patent/JP2008035862A/ja not_active Withdrawn
- 2007-08-08 JP JP2007206901A patent/JP2008035863A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
JP2001517922A (ja) | 2001-10-09 |
JP4073955B2 (ja) | 2008-04-09 |
EP1637600A1 (de) | 2006-03-22 |
US20030180880A1 (en) | 2003-09-25 |
CA2226255A1 (en) | 1997-01-30 |
JP2008035863A (ja) | 2008-02-21 |
DE69635207T2 (de) | 2006-06-22 |
US6468791B1 (en) | 2002-10-22 |
WO1997003192A2 (en) | 1997-01-30 |
EP0846171B1 (de) | 2005-09-21 |
EP0846171A2 (de) | 1998-06-10 |
JP2008035862A (ja) | 2008-02-21 |
DE69635207D1 (de) | 2006-02-02 |
WO1997003192A3 (en) | 1997-04-03 |
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Legal Events
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |