ID25504A - Pencegahan dan pengobatan penyakit amiloidogenik - Google Patents

Pencegahan dan pengobatan penyakit amiloidogenik

Info

Publication number
ID25504A
ID25504A IDW20001293A ID20001293A ID25504A ID 25504 A ID25504 A ID 25504A ID W20001293 A IDW20001293 A ID W20001293A ID 20001293 A ID20001293 A ID 20001293A ID 25504 A ID25504 A ID 25504A
Authority
ID
Indonesia
Prior art keywords
amiloidogenic
disease
prevention
treatment
amiloidogenic disease
Prior art date
Application number
IDW20001293A
Other languages
English (en)
Inventor
Dale B Schenk
Original Assignee
Neuralab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26748211&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ID25504(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Neuralab Ltd filed Critical Neuralab Ltd
Publication of ID25504A publication Critical patent/ID25504A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/739—Lipopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
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    • A61K39/0007—Nervous system antigens; Prions
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
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    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
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    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
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    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
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    • A61K2039/55511—Organic adjuvants
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
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    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
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    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurosurgery (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IDW20001293A 1997-12-02 1998-11-30 Pencegahan dan pengobatan penyakit amiloidogenik ID25504A (id)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6774097P 1997-12-02 1997-12-02
US8097098P 1998-04-07 1998-04-07

Publications (1)

Publication Number Publication Date
ID25504A true ID25504A (id) 2000-10-05

Family

ID=26748211

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20001293A ID25504A (id) 1997-12-02 1998-11-30 Pencegahan dan pengobatan penyakit amiloidogenik

Country Status (37)

Country Link
US (26) US20040171816A1 (id)
EP (5) EP1679080B1 (id)
JP (4) JP4677094B2 (id)
KR (3) KR20120135915A (id)
CN (1) CN100374151C (id)
AR (1) AR020050A1 (id)
AT (4) ATE433760T1 (id)
AU (1) AU1706199A (id)
BG (1) BG104562A (id)
BR (1) BR9815357A (id)
CA (1) CA2312920C (id)
CO (1) CO4980846A1 (id)
CY (3) CY1108331T1 (id)
CZ (1) CZ303137B6 (id)
DE (7) DE69840969D1 (id)
DK (4) DK2305282T3 (id)
EA (3) EA009283B1 (id)
EE (1) EE05377B1 (id)
ES (4) ES2310017T3 (id)
GE (2) GEP20053715B (id)
HR (2) HRP20000443B1 (id)
HU (2) HU228061B1 (id)
ID (1) ID25504A (id)
IL (5) IL136252A0 (id)
IS (1) IS5500A (id)
MY (1) MY134906A (id)
NO (3) NO328865B1 (id)
NZ (1) NZ504569A (id)
PE (1) PE20001383A1 (id)
PL (2) PL202706B1 (id)
PT (4) PT1679080E (id)
SA (1) SA99191269B1 (id)
SG (1) SG111083A1 (id)
SI (4) SI1994937T1 (id)
TR (1) TR200001608T2 (id)
TW (1) TWI239847B (id)
WO (1) WO1999027944A1 (id)

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US6913745B1 (en) 1997-12-02 2005-07-05 Neuralab Limited Passive immunization of Alzheimer's disease
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US7790856B2 (en) 1998-04-07 2010-09-07 Janssen Alzheimer Immunotherapy Humanized antibodies that recognize beta amyloid peptide
US6761888B1 (en) 2000-05-26 2004-07-13 Neuralab Limited Passive immunization treatment of Alzheimer's disease
US7179892B2 (en) * 2000-12-06 2007-02-20 Neuralab Limited Humanized antibodies that recognize beta amyloid peptide
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WO1999060024A1 (en) * 1998-05-21 1999-11-25 The University Of Tennessee Research Corporation Methods for amyloid removal using anti-amyloid antibodies
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NO20002784D0 (no) 2000-05-31
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US20130058869A1 (en) 2013-03-07
NO20092874L (no) 2000-07-31
EP1679080B1 (en) 2009-06-17
CA2312920A1 (en) 1999-06-10
US20040171816A1 (en) 2004-09-02
US20040170641A1 (en) 2004-09-02
GEP20053715B (en) 2005-12-26
EP1994937B1 (en) 2010-12-29
NO331425B1 (no) 2011-12-27
EP2305282B1 (en) 2013-07-10
CY1109368T1 (el) 2014-07-02
US8034339B2 (en) 2011-10-11
US6808712B2 (en) 2004-10-26
EA007218B1 (ru) 2006-08-25
ES2263408T1 (es) 2006-12-16
ES2428740T3 (es) 2013-11-11
US20050249725A1 (en) 2005-11-10
CY1108331T1 (el) 2014-02-12
DE69842082D1 (de) 2011-02-10
JP2006077030A (ja) 2006-03-23
JP2002502802A (ja) 2002-01-29
US20080227719A1 (en) 2008-09-18
IL191904A0 (en) 2008-12-29
EA200000608A1 (ru) 2000-12-25
EP2305282A3 (en) 2011-05-18
US20080227718A1 (en) 2008-09-18
US20050191314A1 (en) 2005-09-01
IL193245A0 (en) 2009-09-22
US20050163788A1 (en) 2005-07-28
CN1281366A (zh) 2001-01-24
EP1679080A3 (en) 2006-07-19
MY134906A (en) 2007-12-31
US20050019330A1 (en) 2005-01-27
US20050019343A1 (en) 2005-01-27
SI1994937T1 (sl) 2011-04-29
CZ303137B6 (cs) 2012-04-25
HUP0100627A3 (en) 2006-03-28
SI1033996T1 (sl) 2009-02-28
DE06075479T1 (de) 2006-11-16
US20050191292A1 (en) 2005-09-01
HU228061B1 (en) 2012-09-28
JP4677094B2 (ja) 2011-04-27
IL136252A0 (en) 2001-05-20
US7014855B2 (en) 2006-03-21
JP4677333B2 (ja) 2011-04-27
PT2305282E (pt) 2013-09-27
DK1033996T3 (da) 2008-09-22
PL342649A1 (en) 2001-06-18
AR020050A1 (es) 2002-04-10
PL202706B1 (pl) 2009-07-31
US20050037026A1 (en) 2005-02-17
HUP0100627A1 (hu) 2001-06-28
ES2263408T3 (es) 2009-11-16
IL191904A (en) 2014-05-28
US20050048049A1 (en) 2005-03-03
US20050013815A1 (en) 2005-01-20
WO1999027944A9 (en) 1999-09-23
PT1679080E (pt) 2009-09-10
IL136252A (en) 2010-11-30
NO20100061L (no) 2000-07-31
ATE435659T1 (de) 2009-07-15
IL205298A0 (en) 2011-07-31
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HU228493B1 (en) 2013-03-28
IS5500A (is) 2000-05-17
PT1994937E (pt) 2011-02-22
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EE200000379A (et) 2001-04-16
US8034348B2 (en) 2011-10-11
DE06075704T1 (de) 2006-12-28
US20060034858A1 (en) 2006-02-16
AU1706199A (en) 1999-06-16
US20080096818A1 (en) 2008-04-24
US20050142132A1 (en) 2005-06-30
SI2305282T1 (sl) 2013-10-30
NZ504569A (en) 2005-01-28
KR20090078366A (ko) 2009-07-17
EP1033996A4 (en) 2004-05-26
TWI239847B (en) 2005-09-21
DK1679080T3 (da) 2009-09-28
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ATE433760T1 (de) 2009-07-15
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NO328865B1 (no) 2010-06-07
BR9815357A (pt) 2000-10-24
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SG111083A1 (en) 2005-05-30
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EE05377B1 (et) 2011-02-15
EP1033996A1 (en) 2000-09-13
CA2312920C (en) 2016-07-12
DE69840922D1 (de) 2009-07-30
KR20120135915A (ko) 2012-12-17
PL202698B1 (pl) 2009-07-31
CZ20001706A3 (cs) 2000-11-15
CO4980846A1 (es) 2000-11-27
TR200001608T2 (tr) 2001-07-23
US20040171815A1 (en) 2004-09-02
US8642044B2 (en) 2014-02-04
EA200601132A1 (ru) 2007-02-27
GEP20043319B (en) 2004-05-10
JP4677334B2 (ja) 2011-04-27
JP2006131639A (ja) 2006-05-25
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US20050249727A1 (en) 2005-11-10
KR100936419B1 (ko) 2010-01-12
EP1679080A2 (en) 2006-07-12
US20050031629A1 (en) 2005-02-10
EP1690547B1 (en) 2009-07-08
EP1994937A3 (en) 2008-12-24
US20060029611A1 (en) 2006-02-09
DK2305282T3 (da) 2013-10-07
DE69840969D1 (de) 2009-08-20
KR20010032635A (ko) 2001-04-25
US8535673B2 (en) 2013-09-17
ATE399016T1 (de) 2008-07-15
US20050196399A1 (en) 2005-09-08
US20040228865A1 (en) 2004-11-18
US20090191231A1 (en) 2009-07-30
US20140227274A1 (en) 2014-08-14
EA009283B1 (ru) 2007-12-28
DE69839647D1 (de) 2008-08-07
SI1679080T1 (sl) 2009-12-31
HRP20000443B1 (hr) 2009-11-30
HRP20090568A2 (hr) 2010-06-30
US6946135B2 (en) 2005-09-20
WO1999027944A1 (en) 1999-06-10
US20120276116A1 (en) 2012-11-01

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