DE68927933D1 - Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen - Google Patents

Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen

Info

Publication number
DE68927933D1
DE68927933D1 DE68927933T DE68927933T DE68927933D1 DE 68927933 D1 DE68927933 D1 DE 68927933D1 DE 68927933 T DE68927933 T DE 68927933T DE 68927933 T DE68927933 T DE 68927933T DE 68927933 D1 DE68927933 D1 DE 68927933D1
Authority
DE
Germany
Prior art keywords
protein
binding domains
family
genetic package
package
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68927933T
Other languages
English (en)
Other versions
DE68927933T2 (de
Inventor
Robert Ladner
Sonia Guterman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dyax Corp
Original Assignee
PROTEIN ENG CORP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22905360&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE68927933(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by PROTEIN ENG CORP filed Critical PROTEIN ENG CORP
Application granted granted Critical
Publication of DE68927933D1 publication Critical patent/DE68927933D1/de
Publication of DE68927933T2 publication Critical patent/DE68927933T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
DE68927933T 1988-09-02 1989-09-01 Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen Expired - Fee Related DE68927933T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24016088A 1988-09-02 1988-09-02
PCT/US1989/003731 WO1990002809A1 (en) 1988-09-02 1989-09-01 Generation and selection of recombinant varied binding proteins

Publications (2)

Publication Number Publication Date
DE68927933D1 true DE68927933D1 (de) 1997-05-07
DE68927933T2 DE68927933T2 (de) 1997-08-14

Family

ID=22905360

Family Applications (2)

Application Number Title Priority Date Filing Date
DE0768377T Pending DE768377T1 (de) 1988-09-02 1989-09-01 Herstellung und Auswahl von Rekombinantproteinen mit verschiedenen Bindestellen
DE68927933T Expired - Fee Related DE68927933T2 (de) 1988-09-02 1989-09-01 Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE0768377T Pending DE768377T1 (de) 1988-09-02 1989-09-01 Herstellung und Auswahl von Rekombinantproteinen mit verschiedenen Bindestellen

Country Status (8)

Country Link
EP (6) EP1026240A3 (de)
JP (1) JP3771253B2 (de)
AT (1) ATE151110T1 (de)
AU (1) AU4308689A (de)
CA (1) CA1340288C (de)
DE (2) DE768377T1 (de)
IL (1) IL91501A (de)
WO (1) WO1990002809A1 (de)

Families Citing this family (1003)

* Cited by examiner, † Cited by third party
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EP1541682A2 (de) 2005-06-15
EP0436597B1 (de) 1997-04-02
DE68927933T2 (de) 1997-08-14
DE768377T1 (de) 1998-01-02
IL91501A0 (en) 1990-04-29
AU4308689A (en) 1990-04-02
EP1026240A3 (de) 2004-04-07
ATE151110T1 (de) 1997-04-15
EP0436597A4 (en) 1992-05-20
EP0768377A1 (de) 1997-04-16
EP1892296A1 (de) 2008-02-27
EP1541682A3 (de) 2005-07-06
EP1997891A1 (de) 2008-12-03
WO1990002809A1 (en) 1990-03-22
JP3771253B2 (ja) 2006-04-26
EP0436597A1 (de) 1991-07-17
EP1026240A2 (de) 2000-08-09
CA1340288C (en) 1998-12-29
IL91501A (en) 1998-03-10

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