ATE43138T1 - Herstellung von dns-sequenzen und deren verwendung zur mikrobiologischen herstellung von proteinen, insbesondere menschlichen serumalbuminen. - Google Patents

Herstellung von dns-sequenzen und deren verwendung zur mikrobiologischen herstellung von proteinen, insbesondere menschlichen serumalbuminen.

Info

Publication number
ATE43138T1
ATE43138T1 AT82304478T AT82304478T ATE43138T1 AT E43138 T1 ATE43138 T1 AT E43138T1 AT 82304478 T AT82304478 T AT 82304478T AT 82304478 T AT82304478 T AT 82304478T AT E43138 T1 ATE43138 T1 AT E43138T1
Authority
AT
Austria
Prior art keywords
production
fragments
human serum
polypeptide
proteins
Prior art date
Application number
AT82304478T
Other languages
English (en)
Inventor
Richard M Lawn
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23146077&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE43138(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE43138T1 publication Critical patent/ATE43138T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
AT82304478T 1981-08-28 1982-08-25 Herstellung von dns-sequenzen und deren verwendung zur mikrobiologischen herstellung von proteinen, insbesondere menschlichen serumalbuminen. ATE43138T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29738081A 1981-08-28 1981-08-28
EP82304478A EP0073646B1 (de) 1981-08-28 1982-08-25 Herstellung von DNS-Sequenzen und deren Verwendung zur mikrobiologischen Herstellung von Proteinen, insbesondere menschlichen Serum-Albuminen

Publications (1)

Publication Number Publication Date
ATE43138T1 true ATE43138T1 (de) 1989-06-15

Family

ID=23146077

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82304478T ATE43138T1 (de) 1981-08-28 1982-08-25 Herstellung von dns-sequenzen und deren verwendung zur mikrobiologischen herstellung von proteinen, insbesondere menschlichen serumalbuminen.

Country Status (14)

Country Link
EP (1) EP0073646B1 (de)
JP (4) JPS5856684A (de)
KR (1) KR840001216A (de)
AT (1) ATE43138T1 (de)
AU (2) AU8775582A (de)
CA (1) CA1221927A (de)
DE (1) DE3279699D1 (de)
DK (1) DK169726B1 (de)
ES (1) ES8401133A1 (de)
GB (2) GB2105343B (de)
IE (1) IE53892B1 (de)
IL (1) IL66614A (de)
NZ (1) NZ201704A (de)
ZA (1) ZA826250B (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0079739A3 (de) * 1981-11-12 1984-08-08 The Upjohn Company Auf Albumin basierende Nukleotiden, ihre Replikation und Verwendung und Plasmide zur Verwendung darin
EP0091527A3 (de) * 1981-12-14 1984-07-25 The President And Fellows Of Harvard College DNS Sequenzen, rekombinante DNS Moleküle und Verfahren zur Herstellung von menschlichem Serum Albumin ähnlichen Polypeptiden
FR2579223B1 (fr) * 1985-03-25 1988-12-09 Genetica Procede de preparation microbiologique de la serum-albumine humaine
EP0206733A1 (de) * 1985-06-17 1986-12-30 Genex Corporation Geklontes menschliches Serumalbumin-Gen
US4956282A (en) * 1985-07-29 1990-09-11 Calgene, Inc. Mammalian peptide expression in plant cells
FR2594846B1 (fr) * 1986-02-21 1989-10-20 Genetica Procede de preparation de la serum albumine humaine mature
IL87258A (en) * 1987-07-28 1994-02-27 Gist Brocades Nv SECYMOREVYULK surrogate cells and their use for the expression of polypeptides
US5879907A (en) * 1987-09-14 1999-03-09 Skandigen Ab Artificial gene coding for authentic human serum albumin, use thereof and method
SE459586B (sv) * 1987-09-14 1989-07-17 Mta Szegedi Biolog Koezponti Strukturgen som kodar foer autentiskt humant serum albumin och foerfarande foer dess framstaellning
GB8725529D0 (en) * 1987-10-30 1987-12-02 Delta Biotechnology Ltd Polypeptides
IL88326A (en) * 1987-11-18 1993-03-15 Gist Brocades Nv Purification of serum albumin
JPH01215289A (ja) * 1988-02-22 1989-08-29 Toa Nenryo Kogyo Kk 遺伝子組換えによる正常ヒト血清アルブミンａの製造方法
US4990447A (en) * 1988-06-24 1991-02-05 Gist-Brocades Nv Process for the purification of serum albumin
US5260202A (en) * 1988-09-07 1993-11-09 Delta Biotechnology Limited Fermentation method
GB8820951D0 (en) * 1988-09-07 1988-10-05 Delta Biotechnology Ltd Fermentation method
US5759802A (en) * 1988-10-26 1998-06-02 Tonen Corporation Production of human serum alubumin A
JPH0671432B2 (ja) * 1991-03-20 1994-09-14 株式会社ミドリ十字 ヒト血清アルブミンの製造方法
CA2058820C (en) * 1991-04-25 2003-07-15 Kotikanyad Sreekrishna Expression cassettes and vectors for the secretion of human serum albumin in pichia pastoris cells
US5330901A (en) * 1991-04-26 1994-07-19 Research Corporation Technologies, Inc. Expression of human serum albumin in Pichia pastoris
US5849874A (en) * 1991-07-12 1998-12-15 Gist-Brocades, N.V. Process for the purification of serum albumin
ATE186547T1 (de) 1991-07-12 1999-11-15 Dsm Nv Verfahren zur reinigung von serumalbumin
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
JPH07102148B2 (ja) * 1992-05-20 1995-11-08 株式会社ミドリ十字 遺伝子操作により得られるヒト血清アルブミンの製造方法、およびそれにより得られるヒト血清アルブミン含有組成物
US5728553A (en) * 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
JPH07308199A (ja) 1994-05-18 1995-11-28 Green Cross Corp:The ヒト血清アルブミンの製造方法
GB9526733D0 (en) 1995-12-30 1996-02-28 Delta Biotechnology Ltd Fusion proteins
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
US6946134B1 (en) 2000-04-12 2005-09-20 Human Genome Sciences, Inc. Albumin fusion proteins
EP1276849A4 (de) 2000-04-12 2004-06-09 Human Genome Sciences Inc Albumin fusionsproteine
JP4798832B2 (ja) 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 ヒト血清アルブミン多量体の除去方法
JP4798833B2 (ja) 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 加熱処理工程を含むヒト血清アルブミンの製造方法
US7507413B2 (en) 2001-04-12 2009-03-24 Human Genome Sciences, Inc. Albumin fusion proteins
EP2277889B1 (de) 2001-12-21 2014-07-09 Human Genome Sciences, Inc. Fusionsproteine von Albumin und Interferon beta
GB0329722D0 (en) 2003-12-23 2004-01-28 Delta Biotechnology Ltd Modified plasmid and use thereof
GB0329681D0 (en) 2003-12-23 2004-01-28 Delta Biotechnology Ltd Gene expression technique
CA2559379A1 (en) 2004-01-20 2005-07-28 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Process for producing human serum albumin by heating in presence of divalent cation
JP4651282B2 (ja) 2004-01-21 2011-03-16 田辺三菱製薬株式会社 造血幹細胞及び造血前駆細胞の増幅方法
JP4492156B2 (ja) 2004-03-03 2010-06-30 ニプロ株式会社 血清アルブミンドメインを含む蛋白質
AU2005317828A1 (en) 2004-12-23 2006-06-29 Novozymes Delta Limited Gene expression technique
RU2010151453A (ru) 2008-05-15 2012-06-20 Р-Тек Уено, Лтд. (Jp) Фармацевтическая композиция для лечения сухости глаз и/или повреждения конъюнктивы и роговицы
JP5936112B2 (ja) 2009-02-11 2016-06-15 アルブミディクス アクティーゼルスカブ アルブミン変異体及び複合体
WO2010115634A1 (en) 2009-04-09 2010-10-14 Cellca Gmbh Method for improved single cell cloning
BR112014000042A2 (pt) 2011-07-05 2017-02-21 Novozymes Biopharma Dk As composição, meio de cultura celular, uso de uma composição, e, método para cultivar células

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4719177A (en) * 1981-04-20 1988-01-12 Massachusetts Institute Of Technology Production of complementary DNA representing RNA viral sequences by recombinant DNA methods and uses therefor
FR2506326A1 (fr) * 1981-05-19 1982-11-26 Pasteur Institut Fragments d'adn portant des parties de l'information genetique des poliovirus, notamment du type pv1, et procede pour leur obtention
EP0079739A3 (de) * 1981-11-12 1984-08-08 The Upjohn Company Auf Albumin basierende Nukleotiden, ihre Replikation und Verwendung und Plasmide zur Verwendung darin
EP0091527A3 (de) * 1981-12-14 1984-07-25 The President And Fellows Of Harvard College DNS Sequenzen, rekombinante DNS Moleküle und Verfahren zur Herstellung von menschlichem Serum Albumin ähnlichen Polypeptiden

Also Published As

Publication number Publication date
ZA826250B (en) 1983-09-28
GB2147903A (en) 1985-05-22
AU8146187A (en) 1988-03-17
JPH08228790A (ja) 1996-09-10
EP0073646A2 (de) 1983-03-09
IE822085L (en) 1983-02-28
IE53892B1 (en) 1989-04-12
JP2968052B2 (ja) 1999-10-25
AU8775582A (en) 1983-03-03
JPH0662841A (ja) 1994-03-08
GB2105343B (en) 1985-12-24
ES515259A0 (es) 1983-12-01
JPH0775538B2 (ja) 1995-08-16
AU603394B2 (en) 1990-11-15
EP0073646A3 (en) 1984-08-01
DE3279699D1 (en) 1989-06-22
KR840001216A (ko) 1984-03-28
JPH0460639B2 (de) 1992-09-28
DK384582A (da) 1983-03-01
EP0073646B1 (de) 1989-05-17
GB2147903B (en) 1985-12-24
NZ201704A (en) 1986-08-08
JPH05292993A (ja) 1993-11-09
CA1221927A (en) 1987-05-19
ES8401133A1 (es) 1983-12-01
IL66614A0 (en) 1982-12-31
GB8423932D0 (en) 1984-10-31
GB2105343A (en) 1983-03-23
IL66614A (en) 1985-09-29
JPS5856684A (ja) 1983-04-04
DK169726B1 (da) 1995-01-23

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time