DE69233155D1 - Insulinartigen wachstumsfaktor bindendes protein - Google Patents

Insulinartigen wachstumsfaktor bindendes protein

Info

Publication number
DE69233155D1
DE69233155D1 DE69233155T DE69233155T DE69233155D1 DE 69233155 D1 DE69233155 D1 DE 69233155D1 DE 69233155 T DE69233155 T DE 69233155T DE 69233155 T DE69233155 T DE 69233155T DE 69233155 D1 DE69233155 D1 DE 69233155D1
Authority
DE
Germany
Prior art keywords
growth factor
insulin
protein
binding protein
igfbp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69233155T
Other languages
English (en)
Other versions
DE69233155T2 (de
Inventor
C Kiefer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Application granted granted Critical
Publication of DE69233155D1 publication Critical patent/DE69233155D1/de
Publication of DE69233155T2 publication Critical patent/DE69233155T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4743—Insulin-like growth factor binding protein
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69233155T 1991-01-08 1992-01-02 Insulinartigen wachstumsfaktor bindendes protein Expired - Fee Related DE69233155T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63862891A 1991-01-08 1991-01-08
US638628 1991-01-08
PCT/US1992/000107 WO1992012243A1 (en) 1991-01-08 1992-01-02 New insulin-like growth factor binding protein (igfbp-6)

Publications (2)

Publication Number Publication Date
DE69233155D1 true DE69233155D1 (de) 2003-10-02
DE69233155T2 DE69233155T2 (de) 2004-06-03

Family

ID=24560804

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69233155T Expired - Fee Related DE69233155T2 (de) 1991-01-08 1992-01-02 Insulinartigen wachstumsfaktor bindendes protein

Country Status (8)

Country Link
US (3) US6500635B1 (de)
EP (1) EP0556344B1 (de)
AT (1) ATE247164T1 (de)
CA (1) CA2100083A1 (de)
DE (1) DE69233155T2 (de)
IE (1) IE920044A1 (de)
PT (1) PT99995B (de)
WO (1) WO1992012243A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69333063T2 (de) 1992-11-04 2004-05-13 Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville Vekürztes insulinähnlichen wachstumsfaktor-bindendes protein mit mitogener aktivität
EP0726911B1 (de) * 1993-09-20 2002-10-30 Celtrix Pharmaceuticals, Inc. Behandlung von hematologischen störungen mit einem igf-1/igfbp-3 komplex
AU710568B2 (en) * 1994-12-09 1999-09-23 Human Genome Sciences, Inc. Human vascular IBP-like growth factor
DK1486565T3 (da) 1995-10-11 2008-03-10 Novartis Vaccines & Diagnostic Kombination af PDGF, KGF, IGF og IGFBP til sårheling
DE19757250A1 (de) * 1997-12-22 1999-07-01 Forssmann Wolf Georg Prof Dr Insulin-like growth factor binding protein und seine Verwendung
WO2000023469A2 (en) * 1998-10-16 2000-04-27 Musc Foundation For Research Development Fragments of insulin-like growth factor binding protein and insulin-like growth factor, and uses thereof
WO2002098914A2 (en) * 2001-06-07 2002-12-12 F. Hoffmann-La Roche Ag Mutants of igf binding proteins and methods of production of antagonists thereof
EP1670822A2 (de) 2003-10-03 2006-06-21 Genentech, Inc. Igf-bindende proteine
DK2444505T3 (da) * 2004-07-23 2017-01-02 Pacific Edge Ltd Urinmarkører til påvisning af blærecancer
NZ545243A (en) 2006-02-10 2009-07-31 Pacific Edge Biotechnology Ltd Urine gene expression ratios for detection of cancer

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK131988A (da) 1988-03-11 1989-09-12 Erasmus University Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur
US5258287A (en) * 1988-03-22 1993-11-02 Genentech, Inc. DNA encoding and methods of production of insulin-like growth factor binding protein BP53
JPH03504597A (ja) * 1988-04-12 1991-10-09 シナージェン，インコーポレーテッド インスリン様成長因子活性の強化および阻害方法
ATE125268T1 (de) * 1988-07-15 1995-08-15 Cent Sydney Area Health Serv Säureempfindliche subeinheit eines insulinähnlichen wachstumfaktors-bindeprotein- komplexes.
GB8826451D0 (en) * 1988-11-11 1988-12-14 Sandoz Ltd Improvements in/relating to organic compounds
WO1992014834A1 (en) * 1991-02-14 1992-09-03 The Whittier Institute For Diabetes And Endocrinology Insulin-like growth factor binding protein
JP2527896B2 (ja) 1991-04-19 1996-08-28 ベーリンガー・マンハイム・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング ヒト骨由来インスリン様成長因子結合タンパク
DE69733286T2 (de) * 1996-08-27 2006-01-19 Trexel, Inc., Woburn Verfahren zum Extrudieren von Mikrozellenpolymeren

Also Published As

Publication number Publication date
DE69233155T2 (de) 2004-06-03
EP0556344B1 (de) 2003-08-13
IE920044A1 (en) 1992-07-15
US20030082744A1 (en) 2003-05-01
CA2100083A1 (en) 1992-07-09
PT99995A (pt) 1993-01-29
EP0556344A1 (de) 1993-08-25
WO1992012243A1 (en) 1992-07-23
US20050136058A1 (en) 2005-06-23
ATE247164T1 (de) 2003-08-15
US6906029B2 (en) 2005-06-14
US6500635B1 (en) 2002-12-31
PT99995B (pt) 1999-06-30
EP0556344A4 (en) 1994-08-24

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS,INC.(N.D.GES, US

8339 Ceased/non-payment of the annual fee