IL66614A - Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it - Google Patents

Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it

Info

Publication number
IL66614A
IL66614A IL66614A IL6661482A IL66614A IL 66614 A IL66614 A IL 66614A IL 66614 A IL66614 A IL 66614A IL 6661482 A IL6661482 A IL 6661482A IL 66614 A IL66614 A IL 66614A
Authority
IL
Israel
Prior art keywords
polypeptide
fragments
serum albumin
human serum
constructing
Prior art date
Application number
IL66614A
Other languages
English (en)
Other versions
IL66614A0 (en
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23146077&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL66614(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of IL66614A0 publication Critical patent/IL66614A0/xx
Publication of IL66614A publication Critical patent/IL66614A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL66614A 1981-08-28 1982-08-23 Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it IL66614A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29738081A 1981-08-28 1981-08-28

Publications (2)

Publication Number Publication Date
IL66614A0 IL66614A0 (en) 1982-12-31
IL66614A true IL66614A (en) 1985-09-29

Family

ID=23146077

Family Applications (1)

Application Number Title Priority Date Filing Date
IL66614A IL66614A (en) 1981-08-28 1982-08-23 Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it

Country Status (14)

Country Link
EP (1) EP0073646B1 (de)
JP (4) JPS5856684A (de)
KR (1) KR840001216A (de)
AT (1) ATE43138T1 (de)
AU (2) AU8775582A (de)
CA (1) CA1221927A (de)
DE (1) DE3279699D1 (de)
DK (1) DK169726B1 (de)
ES (1) ES8401133A1 (de)
GB (2) GB2105343B (de)
IE (1) IE53892B1 (de)
IL (1) IL66614A (de)
NZ (1) NZ201704A (de)
ZA (1) ZA826250B (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0079739A3 (de) * 1981-11-12 1984-08-08 The Upjohn Company Auf Albumin basierende Nukleotiden, ihre Replikation und Verwendung und Plasmide zur Verwendung darin
EP0091527A3 (de) * 1981-12-14 1984-07-25 The President And Fellows Of Harvard College DNS Sequenzen, rekombinante DNS Moleküle und Verfahren zur Herstellung von menschlichem Serum Albumin ähnlichen Polypeptiden
FR2579223B1 (fr) * 1985-03-25 1988-12-09 Genetica Procede de preparation microbiologique de la serum-albumine humaine
AU5890286A (en) * 1985-06-17 1986-12-24 Genex Corp. Cloned human serum albumin gene
US4956282A (en) * 1985-07-29 1990-09-11 Calgene, Inc. Mammalian peptide expression in plant cells
FR2594846B1 (fr) * 1986-02-21 1989-10-20 Genetica Procede de preparation de la serum albumine humaine mature
HU208553B (en) * 1987-07-28 1993-11-29 Gist Brocades Nv Process for producing polypeptides, plasmides coding them and transformed kluyveromyces
US5879907A (en) * 1987-09-14 1999-03-09 Skandigen Ab Artificial gene coding for authentic human serum albumin, use thereof and method
SE459586B (sv) * 1987-09-14 1989-07-17 Mta Szegedi Biolog Koezponti Strukturgen som kodar foer autentiskt humant serum albumin och foerfarande foer dess framstaellning
GB8725529D0 (en) * 1987-10-30 1987-12-02 Delta Biotechnology Ltd Polypeptides
IL88326A (en) * 1987-11-18 1993-03-15 Gist Brocades Nv Purification of serum albumin
JPH01215289A (ja) * 1988-02-22 1989-08-29 Toa Nenryo Kogyo Kk 遺伝子組換えによる正常ヒト血清アルブミンａの製造方法
US4990447A (en) * 1988-06-24 1991-02-05 Gist-Brocades Nv Process for the purification of serum albumin
GB8820951D0 (en) * 1988-09-07 1988-10-05 Delta Biotechnology Ltd Fermentation method
US5260202A (en) * 1988-09-07 1993-11-09 Delta Biotechnology Limited Fermentation method
US5759802A (en) * 1988-10-26 1998-06-02 Tonen Corporation Production of human serum alubumin A
JPH0671432B2 (ja) * 1991-03-20 1994-09-14 株式会社ミドリ十字 ヒト血清アルブミンの製造方法
CA2058820C (en) * 1991-04-25 2003-07-15 Kotikanyad Sreekrishna Expression cassettes and vectors for the secretion of human serum albumin in pichia pastoris cells
US5330901A (en) * 1991-04-26 1994-07-19 Research Corporation Technologies, Inc. Expression of human serum albumin in Pichia pastoris
ES2141715T3 (es) 1991-07-12 2000-04-01 Dsm Nv Procedimiento para la purificacion de albumina de suero.
US5849874A (en) * 1991-07-12 1998-12-15 Gist-Brocades, N.V. Process for the purification of serum albumin
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
JPH07102148B2 (ja) * 1992-05-20 1995-11-08 株式会社ミドリ十字 遺伝子操作により得られるヒト血清アルブミンの製造方法、およびそれにより得られるヒト血清アルブミン含有組成物
US5728553A (en) * 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
JPH07308199A (ja) 1994-05-18 1995-11-28 Green Cross Corp:The ヒト血清アルブミンの製造方法
GB9526733D0 (en) 1995-12-30 1996-02-28 Delta Biotechnology Ltd Fusion proteins
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
US6946134B1 (en) 2000-04-12 2005-09-20 Human Genome Sciences, Inc. Albumin fusion proteins
EP2275557A1 (de) 2000-04-12 2011-01-19 Human Genome Sciences, Inc. Albuminfusionsproteine
JP4798832B2 (ja) 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 ヒト血清アルブミン多量体の除去方法
JP4798833B2 (ja) 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 加熱処理工程を含むヒト血清アルブミンの製造方法
US7507413B2 (en) 2001-04-12 2009-03-24 Human Genome Sciences, Inc. Albumin fusion proteins
EP2990417A1 (de) 2001-12-21 2016-03-02 Human Genome Sciences, Inc. Albumin-insulin-fusionsprotein
EP1594530A4 (de) 2003-01-22 2006-10-11 Human Genome Sciences Inc Albuminfusionsproteine
GB0329681D0 (en) 2003-12-23 2004-01-28 Delta Biotechnology Ltd Gene expression technique
US9057061B2 (en) 2003-12-23 2015-06-16 Novozymes Biopharma Dk A/S Gene expression technique
GB0329722D0 (en) 2003-12-23 2004-01-28 Delta Biotechnology Ltd Modified plasmid and use thereof
EP1710250B1 (de) 2004-01-20 2009-04-15 Juridical Foundation, The Chemo-Sero-Therapeutic Research Institute Verfahren zur herstellung von humanserumalbumin durch wärmebehandlung in gegenwart von zweiwertigem kation
JP4651282B2 (ja) 2004-01-21 2011-03-16 田辺三菱製薬株式会社 造血幹細胞及び造血前駆細胞の増幅方法
JP4492156B2 (ja) 2004-03-03 2010-06-30 ニプロ株式会社 血清アルブミンドメインを含む蛋白質
MX2010012416A (es) 2008-05-15 2010-12-21 R Tech Ueno Ltd Composicion farmaceutica para el tratamiento del ojo seco y/o lesion corneal y conjuntival.
SG172789A1 (en) 2009-02-11 2011-08-29 Novozymes Biopharma Dk As Albumin variants and conjugates
EP2417248B1 (de) 2009-04-09 2019-05-22 Sartorius Stedim Cellca GmbH Verfahren zur verbesserten Einzelzellklonung
JP6247210B2 (ja) 2011-07-05 2017-12-13 アルブミディクス アクティーゼルスカブ アルブミン製剤及び用途
EP4442251A1 (de) 2023-04-05 2024-10-09 Albumedix Ltd Formulierungen und verwendungen davon
WO2025158071A1 (en) 2024-01-26 2025-07-31 Sartorius Albumedix Limited Retroviral preparations containing albumin for enhancing transduction efficiency, uses thereof for cell transduction

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4719177A (en) * 1981-04-20 1988-01-12 Massachusetts Institute Of Technology Production of complementary DNA representing RNA viral sequences by recombinant DNA methods and uses therefor
FR2506326A1 (fr) * 1981-05-19 1982-11-26 Pasteur Institut Fragments d'adn portant des parties de l'information genetique des poliovirus, notamment du type pv1, et procede pour leur obtention
EP0079739A3 (de) * 1981-11-12 1984-08-08 The Upjohn Company Auf Albumin basierende Nukleotiden, ihre Replikation und Verwendung und Plasmide zur Verwendung darin
EP0091527A3 (de) * 1981-12-14 1984-07-25 The President And Fellows Of Harvard College DNS Sequenzen, rekombinante DNS Moleküle und Verfahren zur Herstellung von menschlichem Serum Albumin ähnlichen Polypeptiden

Also Published As

Publication number Publication date
DE3279699D1 (en) 1989-06-22
ES515259A0 (es) 1983-12-01
ES8401133A1 (es) 1983-12-01
GB2105343B (en) 1985-12-24
AU8775582A (en) 1983-03-03
KR840001216A (ko) 1984-03-28
ATE43138T1 (de) 1989-06-15
JPH0460639B2 (de) 1992-09-28
DK384582A (da) 1983-03-01
GB2105343A (en) 1983-03-23
IE53892B1 (en) 1989-04-12
DK169726B1 (da) 1995-01-23
JPH0775538B2 (ja) 1995-08-16
NZ201704A (en) 1986-08-08
GB8423932D0 (en) 1984-10-31
JPS5856684A (ja) 1983-04-04
AU8146187A (en) 1988-03-17
GB2147903B (en) 1985-12-24
ZA826250B (en) 1983-09-28
EP0073646B1 (de) 1989-05-17
GB2147903A (en) 1985-05-22
EP0073646A3 (en) 1984-08-01
JPH05292993A (ja) 1993-11-09
CA1221927A (en) 1987-05-19
JPH0662841A (ja) 1994-03-08
EP0073646A2 (de) 1983-03-09
IE822085L (en) 1983-02-28
IL66614A0 (en) 1982-12-31
JP2968052B2 (ja) 1999-10-25
JPH08228790A (ja) 1996-09-10
AU603394B2 (en) 1990-11-15

Similar Documents

Publication Publication Date Title
IL66614A (en) Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it
Wolfe et al. The isolation of homogeneous leader peptidase from a strain of Escherichia coli which overproduces the enzyme.
KR890014738A (ko) 단백질 합성의 cks 방법
KR830005355A (ko) 박테리아숙주내에서 각종 폴리펩타이드를 합성하는 방법 및 폴리펩타이드 dna
DE69532968D1 (de) Verfahren zur sekretion thrombopoitin polypeptide
UA48105C2 (uk) ФРАГМЕНТ ДНК, ЯКИЙ КОДУЄ БІЛОК РОДИНИ TGF-<font face="Symbol">b</font> (ВАРІАНТИ), РЕКОМБІНАНТНА МОЛЕКУЛА ДНК (ВАРІАНТИ), КЛІТИНА-ХАЗЯЇН (ВАРІАНТИ), СПОСІБ ОДЕРЖАННЯ БІЛКУ РОДИНИ TGF-<font face="Symbol">b</font> (ВАРІАНТИ), БІЛОК РОДИНИ TGF-<font face="Symbol">b</font> (ВАРІАНТИ), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ (ВАРІАНТИ), АНТИТІЛО АБО ФРАГМЕНТ АНТИТІЛА (ВАРІАНТИ), МОЛЕКУЛА КДНК (ВАРІАНТИ)
ES2056799T3 (es) Moleculas de adn codante para las regiones de control fmdh y gen estructural para una proteina que tiene una actividad de fmdh y su uso.
HUT47638A (en) Dna structures comprising kluyveromyces alpha-factor leading sequence regulating the selection of heterologous polypeptides
WO1994018316A3 (en) Apolipoprotein b mrna editing protein compositions and methods
EP0048970A3 (de) Polypeptide, Verfahren zu ihrer mikrobischen Herstellung, Zwischenprodukte dafür und diese enthaltende Zusammensetzungen
DE69839553D1 (de) Verfahren zur herstellung von proteinen
DE3855084D1 (de) Herstellung und Reinigung eines Proteins, das mit einem Bindungsprotein fusioniert ist
IE822479L (en) Dna molecules encoding certain mammalian proteins
HUT46061A (en) Dna sequences encoding hirudin-like protein and process for producing such proteins
PT82428B (pt) Metodo para a producao de urocinase resistente a proteases
KR910004803A (ko) 간의 실질 세포 성장 인자, 이를 코딩하는 유전자, 이 인자를 생산하는 방법, 및 이 인자를 생산하는 형질전환체
ES8600403A1 (es) Un procedimiento para producir un peptido que comprende un peptido de exo-senal unido operativamente a una proteina deseada
AU577810B2 (en) Cloning the gene for rabbit tumor necrosis factor polypeptide
SE8101665L (sv) Polypeptidframstellning
DK0629238T3 (da) Autotaxin:Motilitetsstimulerende protein, som er nyttigt til cancerdiagnose og terapi
IE831099L (en) Cloning vehicles for polypeptide expression in microbial¹hosts
SE8800378D0 (sv) Production of fused proteins or polypeptides
KR850001286A (ko) 개량 플라스미드 벡타의 제조방법
KR920004577A (ko) 단백질 합성의 cks 방법
Davidson Apolipoprotein b mRNA editing protein compositions and methods

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
EXP Patent expired