DE69132814D1 - Neues insulinähnliches wachstumsfaktor bindendes protein igfbp-5 - Google Patents

Neues insulinähnliches wachstumsfaktor bindendes protein igfbp-5

Info

Publication number
DE69132814D1
DE69132814D1 DE69132814T DE69132814T DE69132814D1 DE 69132814 D1 DE69132814 D1 DE 69132814D1 DE 69132814 T DE69132814 T DE 69132814T DE 69132814 T DE69132814 T DE 69132814T DE 69132814 D1 DE69132814 D1 DE 69132814D1
Authority
DE
Germany
Prior art keywords
growth factor
binding protein
protein
dna molecules
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69132814T
Other languages
English (en)
Other versions
DE69132814T2 (de
Inventor
C Kiefer
Frank Masiarz
Johann Zapf
Hans Born
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Application granted granted Critical
Publication of DE69132814D1 publication Critical patent/DE69132814D1/de
Publication of DE69132814T2 publication Critical patent/DE69132814T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4743—Insulin-like growth factor binding protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69132814T 1990-08-28 1991-08-28 Neues insulinähnliches wachstumsfaktor bindendes protein igfbp-5 Expired - Fee Related DE69132814T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57461390A 1990-08-28 1990-08-28
US57739190A 1990-08-31 1990-08-31
PCT/US1991/006141 WO1992003471A1 (en) 1990-08-28 1991-08-28 New insulin-like growth factor binding protein igfbp-5

Publications (2)

Publication Number Publication Date
DE69132814D1 true DE69132814D1 (de) 2002-01-03
DE69132814T2 DE69132814T2 (de) 2002-06-13

Family

ID=27076437

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69132814T Expired - Fee Related DE69132814T2 (de) 1990-08-28 1991-08-28 Neues insulinähnliches wachstumsfaktor bindendes protein igfbp-5

Country Status (8)

Country Link
EP (1) EP0546110B1 (de)
JP (1) JPH06503949A (de)
AT (1) ATE208816T1 (de)
CA (1) CA2090702A1 (de)
DE (1) DE69132814T2 (de)
IE (1) IE913034A1 (de)
PT (1) PT98805B (de)
WO (1) WO1992003471A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5969124A (en) * 1992-06-26 1999-10-19 Case Western Reserve University Nucleotide sequence of L1CAM
WO1994010207A2 (en) 1992-11-04 1994-05-11 Chiron Corporation Truncated insulin-like growth factor binding proteins having mitogenic activity
WO1994016723A2 (en) * 1993-01-29 1994-08-04 Synergen, Inc. Wound healing composition
US5847099A (en) * 1994-10-19 1998-12-08 Genetics Institute, Inc. TNF receptor death domain ligand proteins
US5712381A (en) * 1994-10-19 1998-01-27 Genetics Institute, Inc. MADD, a TNF receptor death domain ligand protein
US5849501A (en) * 1994-10-19 1998-12-15 Genetics Institute, Inc. TNF receptor death domain ligand proteins and method to identify inhibitors of ligand binding
US5852173A (en) * 1994-10-19 1998-12-22 Genetics Institute, Inc. TNF receptor death ligand proteins and inhibitors of ligand binding
EP0796325A4 (de) * 1994-12-09 1999-11-03 Human Genome Sciences Inc Menschlicher, vaskulärer ibp-änhlicher wachstumsfaktor
DE69637332T2 (de) 1995-10-11 2008-10-09 Novartis Vaccines and Diagnostics, Inc., Emeryville Kombinierung von PDGF, KGF, IGF und IGFBP für Wundheilung
JP2002532092A (ja) * 1998-12-18 2002-10-02 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド プロスタサイクリン刺激因子−２
EP1873244A3 (de) * 1999-06-02 2008-04-02 Genentech, Inc. Verfahren und Zusammensetzungen zur Hemmung des neoplastischen Zellenwachstums
US7491816B2 (en) 1999-07-19 2009-02-17 The University Of British Columbia Antisense therapy for hormone-regulated tumors
ATE393220T1 (de) 1999-07-19 2008-05-15 Univ British Columbia Antisense-therapie für hormonregulierte tumoren
WO2002060163A2 (en) * 2000-10-24 2002-08-01 Andress Dennis L Methods for increasing bone formation and enhancing bone accretion
AUPR633101A0 (en) * 2001-07-13 2001-08-02 University Of Sydney, The Method
US6750019B2 (en) 2001-10-09 2004-06-15 Isis Pharmaceuticals, Inc. Antisense modulation of insulin-like growth factor binding protein 5 expression
AU2002334895B2 (en) 2001-10-09 2006-10-19 Isis Pharmaceuticals, Inc. Antisense modulation of insulin-like growth factor binding protein 5 expression
EP1465995B1 (de) 2002-01-17 2008-07-30 The University of British Columbia Bispezifische antisense oligonukleotide die igfbp-2 und igfbp-5 inhibieren und deren verwendung
US7538195B2 (en) 2002-06-14 2009-05-26 Immunogen Inc. Anti-IGF-I receptor antibody
WO2005030260A1 (en) 2003-10-01 2005-04-07 The University Of British Columbia Bispecific oligonucleotide for the treatment of cns malignancies
JP2007537711A (ja) 2003-10-03 2007-12-27 ジェネンテック・インコーポレーテッド Ｉｇｆ結合タンパク質
WO2007122975A1 (ja) 2006-04-20 2007-11-01 Kringle Pharma Inc. Ｈｇｆ前駆体蛋白質改変体及びその活性型蛋白質

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK131988A (da) * 1988-03-11 1989-09-12 Erasmus University Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur

Also Published As

Publication number Publication date
WO1992003471A1 (en) 1992-03-05
EP0546110A4 (en) 1994-08-17
IE913034A1 (en) 1992-03-11
PT98805B (pt) 1999-01-29
JPH06503949A (ja) 1994-05-12
PT98805A (pt) 1992-08-31
EP0546110A1 (de) 1993-06-16
DE69132814T2 (de) 2002-06-13
EP0546110B1 (de) 2001-11-14
ATE208816T1 (de) 2001-11-15
CA2090702A1 (en) 1992-03-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS VACCINES AND DIAGNOSTICS,INC.(N.D.GES, US

8339 Ceased/non-payment of the annual fee