ATE63335T1 - Herstellung von rekombinantem protein. - Google Patents
Herstellung von rekombinantem protein.Info
- Publication number
- ATE63335T1 ATE63335T1 AT87109276T AT87109276T ATE63335T1 AT E63335 T1 ATE63335 T1 AT E63335T1 AT 87109276 T AT87109276 T AT 87109276T AT 87109276 T AT87109276 T AT 87109276T AT E63335 T1 ATE63335 T1 AT E63335T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- recombinant protein
- lipoprotein
- culturing
- enhanced
- Prior art date
Links
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 title 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 title 1
- 108010054218 Factor VIII Proteins 0.000 abstract 1
- 102000001690 Factor VIII Human genes 0.000 abstract 1
- 108090001030 Lipoproteins Proteins 0.000 abstract 1
- 102000004895 Lipoproteins Human genes 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 229960000301 factor viii Drugs 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88441286A | 1986-07-11 | 1986-07-11 | |
| EP87109276A EP0254076B1 (de) | 1986-07-11 | 1987-06-27 | Herstellung von rekombinantem Protein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE63335T1 true ATE63335T1 (de) | 1991-05-15 |
Family
ID=25384571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87109276T ATE63335T1 (de) | 1986-07-11 | 1987-06-27 | Herstellung von rekombinantem protein. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0254076B1 (de) |
| JP (1) | JPH0630610B2 (de) |
| AT (1) | ATE63335T1 (de) |
| DE (1) | DE3769872D1 (de) |
| DK (1) | DK359487A (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5198349A (en) * | 1986-01-03 | 1993-03-30 | Genetics Institute, Inc. | Method for producing factor VIII:C and analogs |
| DE3785102T2 (de) * | 1986-01-03 | 1993-07-22 | Genetics Inst | Verfahren zur herstellung von faktor-viii:c-typ-proteinen. |
| US5595886A (en) * | 1986-01-27 | 1997-01-21 | Chiron Corporation | Protein complexes having Factor VIII:C activity and production thereof |
| US6060447A (en) * | 1987-05-19 | 2000-05-09 | Chiron Corporation | Protein complexes having Factor VIII:C activity and production thereof |
| DE69004964T2 (de) * | 1989-08-11 | 1994-03-24 | Zymogenetics Inc | Zellenzuchtverfahren für die produktion von aktiviertem protein-c. |
| FR2657884B1 (fr) * | 1990-02-05 | 1994-09-02 | Tm Innovation | Procede pour la preparation du facteur viii humain et d'analogues du facteur viii. |
| DK53792D0 (da) * | 1992-04-24 | 1992-04-24 | Novo Nordisk As | Fremgangsmaade til fremstilling af proteiner |
| AU5462694A (en) * | 1992-11-17 | 1994-06-08 | Novo Nordisk A/S | Improved recombinant production of proteins having factor viii:c activity |
| US5952198A (en) * | 1995-05-04 | 1999-09-14 | Bayer Corporation | Production of recombinant Factor VIII in the presence of liposome-like substances of mixed composition |
| US6358703B1 (en) * | 1998-12-10 | 2002-03-19 | Bayer Corporation | Expression system for factor VIII |
| EP1707634A1 (de) | 2005-03-29 | 2006-10-04 | Octapharma AG | Verfahren zur Isolierung von rekombinant hergestellten Proteinen |
| EP1739179A1 (de) | 2005-06-30 | 2007-01-03 | Octapharma AG | Serumfreie stabile Transfektion und Produktion von rekombinanten humanen Proteinen in humanen Zelllinien |
| EP1988101A1 (de) | 2007-05-04 | 2008-11-05 | Novo Nordisk A/S | Verbesserung von Faktor-VIII-Polypeptid-Titern in Zellkulturen |
| WO2011095604A1 (en) | 2010-02-04 | 2011-08-11 | Octapharma Biopharmaceuticals Gmbh | Half-life prolongation of proteins |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2125409B (en) | 1982-08-04 | 1985-11-13 | Nat Res Dev | Genetic engineering |
| JPH07106156B2 (ja) | 1983-10-28 | 1995-11-15 | ジェネティックス、インスティチュ−ト | ファクタ−▲viii▼および関連生産物の製造 |
| DE3586402T3 (de) | 1984-01-12 | 2004-12-23 | Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville | Proteinzusammensetzung mit Koagulations-wirkung und Verfahren zu ihrer Herstellung. |
| ZA852099B (en) | 1984-03-26 | 1985-12-24 | Meloy Lab | Recombinant factor viii-c. |
| FI86885C (fi) | 1984-04-20 | 1992-10-26 | Genentech Inc | Foerfarande foer framstaellning av human rekombinantfaktor viii och nukleinsyrasekvenser och vektorer anvaend daertill |
| JPS6163283A (ja) * | 1984-09-03 | 1986-04-01 | Teijin Ltd | ハイブリ−ド−マの培養方法 |
-
1987
- 1987-06-27 AT AT87109276T patent/ATE63335T1/de not_active IP Right Cessation
- 1987-06-27 EP EP87109276A patent/EP0254076B1/de not_active Expired - Lifetime
- 1987-06-27 DE DE8787109276T patent/DE3769872D1/de not_active Revoked
- 1987-07-09 JP JP62169926A patent/JPH0630610B2/ja not_active Expired - Lifetime
- 1987-07-10 DK DK359487A patent/DK359487A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0630610B2 (ja) | 1994-04-27 |
| DK359487D0 (da) | 1987-07-10 |
| JPS6342699A (ja) | 1988-02-23 |
| EP0254076A1 (de) | 1988-01-27 |
| EP0254076B1 (de) | 1991-05-08 |
| DE3769872D1 (de) | 1991-06-13 |
| DK359487A (da) | 1988-01-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| RZN | Patent revoked |