ATE157702T1 - Alkalische phosphatase mit verbesserter spezifischer aktivität zur verwendung in indikatorreagenzien - Google Patents

Alkalische phosphatase mit verbesserter spezifischer aktivität zur verwendung in indikatorreagenzien

Info

Publication number
ATE157702T1
ATE157702T1 AT91101338T AT91101338T ATE157702T1 AT E157702 T1 ATE157702 T1 AT E157702T1 AT 91101338 T AT91101338 T AT 91101338T AT 91101338 T AT91101338 T AT 91101338T AT E157702 T1 ATE157702 T1 AT E157702T1
Authority
AT
Austria
Prior art keywords
alkaline phosphatase
specific activity
image
improved specific
indicator reagents
Prior art date
Application number
AT91101338T
Other languages
English (en)
Inventor
Wlodzimierz Mandecki
Susan J Tomazic-Allen
Mary Ann Shallcross
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE157702T1 publication Critical patent/ATE157702T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
AT91101338T 1990-02-07 1991-02-01 Alkalische phosphatase mit verbesserter spezifischer aktivität zur verwendung in indikatorreagenzien ATE157702T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47619990A 1990-02-07 1990-02-07

Publications (1)

Publication Number Publication Date
ATE157702T1 true ATE157702T1 (de) 1997-09-15

Family

ID=23890914

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91101338T ATE157702T1 (de) 1990-02-07 1991-02-01 Alkalische phosphatase mit verbesserter spezifischer aktivität zur verwendung in indikatorreagenzien

Country Status (8)

Country Link
EP (1) EP0441252B1 (de)
JP (1) JP2620416B2 (de)
KR (1) KR910015700A (de)
AT (1) ATE157702T1 (de)
AU (1) AU656313B2 (de)
CA (1) CA2035826A1 (de)
DE (1) DE69127482T2 (de)
ES (1) ES2106737T3 (de)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994001531A1 (en) * 1992-07-07 1994-01-20 Abbott Laboratories Alkaline phosphatase enzymes having improved specific activity for use in indicator reagents
US5304472A (en) * 1992-11-20 1994-04-19 Genentech, Inc. Method of controlling polypeptide production in bacterial cells
EP0688364A4 (de) * 1993-03-09 1997-10-15 Abbott Lab Gentechnologisch hergestellte enzyme und ihre konjugate für diagnostische tests
WO1995005455A1 (en) * 1993-08-13 1995-02-23 Rijksuniversiteit Te Groningen Pharmaceutical composition comprising phosphatase or a derivative thereof
JP2000501606A (ja) * 1995-12-07 2000-02-15 リコンビナント バイオカタリシス，インコーポレーテッド 酵素活性をスクリーニングする方法
US6183740B1 (en) 1997-08-13 2001-02-06 Diversa Corporation Recombinant bacterial phytases and uses thereof
US7432097B2 (en) 1997-08-13 2008-10-07 Verenium Corporation Phytases, nucleic acids encoding them and methods of making and using them
US7078035B2 (en) 1997-08-13 2006-07-18 Diversa Corporation Phytases, nucleic acids encoding them and methods for making and using them
US6720014B1 (en) 1997-08-13 2004-04-13 Diversa Corporation Phytase-containing foodstuffs and methods of making and using them
US8010174B2 (en) 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US8260393B2 (en) 2003-07-25 2012-09-04 Dexcom, Inc. Systems and methods for replacing signal data artifacts in a glucose sensor data stream
US9282925B2 (en) 2002-02-12 2016-03-15 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
WO2004076628A2 (en) 2003-02-24 2004-09-10 New England Biolabs, Inc. Overexpression, purification and characterization of a thermolabile phosphatase
US8423113B2 (en) 2003-07-25 2013-04-16 Dexcom, Inc. Systems and methods for processing sensor data
US8761856B2 (en) 2003-08-01 2014-06-24 Dexcom, Inc. System and methods for processing analyte sensor data
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US7778680B2 (en) 2003-08-01 2010-08-17 Dexcom, Inc. System and methods for processing analyte sensor data
US7519408B2 (en) 2003-11-19 2009-04-14 Dexcom, Inc. Integrated receiver for continuous analyte sensor
US8369919B2 (en) 2003-08-01 2013-02-05 Dexcom, Inc. Systems and methods for processing sensor data
US8160669B2 (en) 2003-08-01 2012-04-17 Dexcom, Inc. Transcutaneous analyte sensor
US8275437B2 (en) 2003-08-01 2012-09-25 Dexcom, Inc. Transcutaneous analyte sensor
US20190357827A1 (en) 2003-08-01 2019-11-28 Dexcom, Inc. Analyte sensor
US20100168542A1 (en) 2003-08-01 2010-07-01 Dexcom, Inc. System and methods for processing analyte sensor data
US7774145B2 (en) 2003-08-01 2010-08-10 Dexcom, Inc. Transcutaneous analyte sensor
US7925321B2 (en) 2003-08-01 2011-04-12 Dexcom, Inc. System and methods for processing analyte sensor data
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US8233959B2 (en) 2003-08-22 2012-07-31 Dexcom, Inc. Systems and methods for processing analyte sensor data
US20140121989A1 (en) 2003-08-22 2014-05-01 Dexcom, Inc. Systems and methods for processing analyte sensor data
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8364231B2 (en) 2006-10-04 2013-01-29 Dexcom, Inc. Analyte sensor
EP2239567B1 (de) 2003-12-05 2015-09-02 DexCom, Inc. Kalibrierverfahren für einen kontinuierlichen Analytsensor
US8774886B2 (en) 2006-10-04 2014-07-08 Dexcom, Inc. Analyte sensor
US11633133B2 (en) 2003-12-05 2023-04-25 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
EP2316331B1 (de) 2003-12-09 2016-06-29 Dexcom, Inc. Signalverarbeitung in einem durchgehenden Analytsensor
US8808228B2 (en) 2004-02-26 2014-08-19 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US8989833B2 (en) 2004-07-13 2015-03-24 Dexcom, Inc. Transcutaneous analyte sensor
US7857760B2 (en) 2004-07-13 2010-12-28 Dexcom, Inc. Analyte sensor
US8452368B2 (en) 2004-07-13 2013-05-28 Dexcom, Inc. Transcutaneous analyte sensor
EP1985697A1 (de) 2007-04-27 2008-10-29 AM-Pharma B.V. Modifizierte Phosphatasen
US20080306434A1 (en) 2007-06-08 2008-12-11 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
EP2227132B1 (de) 2007-10-09 2023-03-08 DexCom, Inc. Integriertes insulin-abgabesystem mit kontinuierlichem glucosesensor
US8591455B2 (en) 2008-02-21 2013-11-26 Dexcom, Inc. Systems and methods for customizing delivery of sensor data
US20110004085A1 (en) 2009-04-30 2011-01-06 Dexcom, Inc. Performance reports associated with continuous sensor data from multiple analysis time periods
CN106011159A (zh) 2009-05-21 2016-10-12 巴斯夫酶有限责任公司 肌醇六磷酸酶、编码它们的核酸及制备和使用它们的方法
US9848809B2 (en) 2011-04-15 2017-12-26 Dexcom, Inc. Advanced analyte sensor calibration and error detection
EP2620162A1 (de) 2012-01-27 2013-07-31 Life Science Inkubator Enzym-Polymer-Konjugat zur Endotoxin-Detoxifikation
CA2864887C (en) * 2012-02-16 2017-04-25 Eli Lilly And Company Methods and compositions for reducing the environmental impact of animal waste
JP5866715B2 (ja) 2013-10-18 2016-02-17 国立大学法人九州大学 タンパク質検出用融合タンパク質およびタンパク質の検出方法
EP3425048A1 (de) 2014-01-24 2019-01-09 AM-Pharma B.V. Chimäre alkalische phosphataseartige proteine
HUE040230T2 (hu) 2014-01-24 2019-02-28 Am Pharma Bv Egy alkálikus foszfatáz feldolgozási folyamata
EP3928687B1 (de) 2017-10-24 2024-06-26 Dexcom, Inc. Tragbare vorrichtung mit vorverbundenem analytsensor
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors

Also Published As

Publication number Publication date
AU656313B2 (en) 1995-02-02
KR910015700A (ko) 1991-09-30
EP0441252A3 (en) 1991-11-21
AU7083791A (en) 1991-08-08
CA2035826A1 (en) 1991-08-08
EP0441252A2 (de) 1991-08-14
EP0441252B1 (de) 1997-09-03
JPH04349881A (ja) 1992-12-04
DE69127482T2 (de) 1998-03-19
DE69127482D1 (de) 1997-10-09
ES2106737T3 (es) 1997-11-16
JP2620416B2 (ja) 1997-06-11

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