DE69128362T2 - Zusammensetzungen und verfahren zur identifizierung von molekülen mit biologischer wirksamkeit - Google Patents

Zusammensetzungen und verfahren zur identifizierung von molekülen mit biologischer wirksamkeit

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Publication number
DE69128362T2
DE69128362T2 DE69128362T DE69128362T DE69128362T2 DE 69128362 T2 DE69128362 T2 DE 69128362T2 DE 69128362 T DE69128362 T DE 69128362T DE 69128362 T DE69128362 T DE 69128362T DE 69128362 T2 DE69128362 T2 DE 69128362T2
Authority
DE
Germany
Prior art keywords
compositions
identifying molecules
biological effectiveness
molecules
identifying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69128362T
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English (en)
Other versions
DE69128362D1 (de
Inventor
James Devlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of DE69128362D1 publication Critical patent/DE69128362D1/de
Application granted granted Critical
Publication of DE69128362T2 publication Critical patent/DE69128362T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2/00—Peptides of undefined number of amino acids; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K4/00—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/14011—Details ssDNA Bacteriophages
    • C12N2795/14022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
DE69128362T 1990-06-01 1991-05-13 Zusammensetzungen und verfahren zur identifizierung von molekülen mit biologischer wirksamkeit Expired - Fee Related DE69128362T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53318090A 1990-06-01 1990-06-01
PCT/US1991/003332 WO1991018980A1 (en) 1990-06-01 1991-05-13 Compositions and methods for identifying biologically active molecules

Publications (2)

Publication Number Publication Date
DE69128362D1 DE69128362D1 (de) 1998-01-15
DE69128362T2 true DE69128362T2 (de) 1998-05-20

Family

ID=24124831

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69128362T Expired - Fee Related DE69128362T2 (de) 1990-06-01 1991-05-13 Zusammensetzungen und verfahren zur identifizierung von molekülen mit biologischer wirksamkeit

Country Status (10)

Country Link
EP (1) EP0600866B1 (de)
JP (1) JPH05507700A (de)
AT (1) ATE160818T1 (de)
AU (2) AU8081491A (de)
CA (1) CA2084307A1 (de)
DE (1) DE69128362T2 (de)
DK (1) DK0600866T3 (de)
ES (1) ES2109945T3 (de)
GR (1) GR3025596T3 (de)
WO (1) WO1991018980A1 (de)

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EP0600866B1 (de) 1997-12-03
CA2084307A1 (en) 1991-12-02
AU8081491A (en) 1991-12-31
ATE160818T1 (de) 1997-12-15
GR3025596T3 (en) 1998-03-31
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EP0600866A1 (de) 1994-06-15
WO1991018980A1 (en) 1991-12-12

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