CY1112362T1 - Πολυμερη βασιζομενα σε κυκλοδεξτρινη για χορηγηση των θεραπευτικων μεσων που ειναι ομοιοπολικως δεσμευμενα σε αυτα - Google Patents

Πολυμερη βασιζομενα σε κυκλοδεξτρινη για χορηγηση των θεραπευτικων μεσων που ειναι ομοιοπολικως δεσμευμενα σε αυτα

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Publication number
CY1112362T1
CY1112362T1 CY20121100157T CY121100157T CY1112362T1 CY 1112362 T1 CY1112362 T1 CY 1112362T1 CY 20121100157 T CY20121100157 T CY 20121100157T CY 121100157 T CY121100157 T CY 121100157T CY 1112362 T1 CY1112362 T1 CY 1112362T1
Authority
CY
Cyprus
Prior art keywords
cyclodextrin
therapeutic
therapeutic agents
methods
therapeutically
Prior art date
Application number
CY20121100157T
Other languages
English (en)
Inventor
Jianjun Cheng
Mark E Davis
Kay T Khin
Original Assignee
Cerulean Pharma Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31982363&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1112362(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cerulean Pharma Inc. filed Critical Cerulean Pharma Inc.
Publication of CY1112362T1 publication Critical patent/CY1112362T1/el

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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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Abstract

Η παρούσα εφεύρεση σχετίζεται με νέες συνθέσεις θεραπευτικών κυκλοδεξτρινούχων πολυμερικών ενώσεων σχεδιασμένων ως φορέας για χορήγηση μικρομοριακών θεραπευτικών ουσιών και με φαρμακευτικές συνθέσεις αυτών. Αυτά τα κυκλοδεξτρινούχα πολυμερή βελτιώνουν τη σταθερότητα και διαλυτότητα της φαρμακευτικής ουσίας, και ελαττώνουν την τοξικότητα της μικρομοριακής θεραπευτικής ουσίας όταν χρησιμοποιούνται in vivo. Περαιτέρω, μέσω επιλογής από ποικιλία ομάδων αρθρωτή και συνδετών στοχοποίησης, τα πολυμερή προσφέρουν μεθόδους για ελεγχόμενη χορήγηση των θεραπευτικών μέσων. Η εφεύρεση επίσης σχετίζεται με μεθόδους αγωγής εξεταζόμενων με τις θεραπευτικές συνθέσεις που περιγράφονται στο κείμενο. Η εφεύρεση περαιτέρω σχετίζεται με μεθόδους για πραγματοποίηση φαρμακευτικής επιχειρηματικότητας που περιλαμβάνουν παραγωγή, αδειοδότηση, ή διανομή κιτ περιέχοντων ή σχετιζόμενων με τις πολυμερικές ενώσεις που περιγράφονται στο κείμενο.
CY20121100157T 2002-09-06 2012-02-16 Πολυμερη βασιζομενα σε κυκλοδεξτρινη για χορηγηση των θεραπευτικων μεσων που ειναι ομοιοπολικως δεσμευμενα σε αυτα CY1112362T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US40885502P 2002-09-06 2002-09-06
US42283002P 2002-10-31 2002-10-31
US45199803P 2003-03-04 2003-03-04
EP03770286A EP1534340B1 (en) 2002-09-06 2003-09-04 Cyclodextrin-based polymers for delivering the therapeutic agents covalently bound thereto

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CY1112362T1 true CY1112362T1 (el) 2015-12-09

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CY20121100157T CY1112362T1 (el) 2002-09-06 2012-02-16 Πολυμερη βασιζομενα σε κυκλοδεξτρινη για χορηγηση των θεραπευτικων μεσων που ειναι ομοιοπολικως δεσμευμενα σε αυτα
CY20131100656T CY1114941T1 (el) 2002-09-06 2013-07-31 Πολυμερη βασιζομενα σε κυκλοδεξτρινη για χορηγηση των θεραπευτικων μεσων που ειναι ομοιοπολικως δεσμευμενα σε αυτα

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