ATE532790T1 - Einschlussverbindung mit cucurbiturilderivaten als wirtsmolekül, und diese enthaltende pharmazeutische zusammensetzung - Google Patents
Einschlussverbindung mit cucurbiturilderivaten als wirtsmolekül, und diese enthaltende pharmazeutische zusammensetzungInfo
- Publication number
- ATE532790T1 ATE532790T1 AT02765666T AT02765666T ATE532790T1 AT E532790 T1 ATE532790 T1 AT E532790T1 AT 02765666 T AT02765666 T AT 02765666T AT 02765666 T AT02765666 T AT 02765666T AT E532790 T1 ATE532790 T1 AT E532790T1
- Authority
- AT
- Austria
- Prior art keywords
- pharmaceutical composition
- host molecule
- composition containing
- containing same
- include compound
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- MSBXTPRURXJCPF-DQWIULQBSA-N cucurbit[6]uril Chemical class N1([C@@H]2[C@@H]3N(C1=O)CN1[C@@H]4[C@@H]5N(C1=O)CN1[C@@H]6[C@@H]7N(C1=O)CN1[C@@H]8[C@@H]9N(C1=O)CN([C@H]1N(C%10=O)CN9C(=O)N8CN7C(=O)N6CN5C(=O)N4CN3C(=O)N2C2)C3=O)CN4C(=O)N5[C@@H]6[C@H]4N2C(=O)N6CN%10[C@H]1N3C5 MSBXTPRURXJCPF-DQWIULQBSA-N 0.000 title abstract 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 abstract 2
- 230000001093 anti-cancer Effects 0.000 abstract 1
- 150000004696 coordination complex Chemical class 0.000 abstract 1
- 230000000857 drug effect Effects 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 229910052697 platinum Inorganic materials 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2001-0057573A KR100484504B1 (ko) | 2001-09-18 | 2001-09-18 | 쿠커비투릴 유도체를 주인 분자로서 포함하고 있는 내포화합물 및 이를 포함한 약제학적 조성물 |
| PCT/KR2002/001755 WO2003024978A1 (en) | 2001-09-18 | 2002-09-18 | Inclusion compound comprising cucurbituril derivatives as host molecule and pharmaceutical composition comprising the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE532790T1 true ATE532790T1 (de) | 2011-11-15 |
Family
ID=19714392
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02765666T ATE532790T1 (de) | 2001-09-18 | 2002-09-18 | Einschlussverbindung mit cucurbiturilderivaten als wirtsmolekül, und diese enthaltende pharmazeutische zusammensetzung |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7459471B2 (de) |
| EP (1) | EP1430061B1 (de) |
| JP (1) | JP4347693B2 (de) |
| KR (1) | KR100484504B1 (de) |
| AT (1) | ATE532790T1 (de) |
| AU (1) | AU2002329097B2 (de) |
| WO (1) | WO2003024978A1 (de) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100499275B1 (ko) * | 2002-01-03 | 2005-07-01 | 학교법인 포항공과대학교 | 하이드록시쿠커비투릴 및 그 유도체, 그 제조방법 및이들의 용도 |
| KR100528959B1 (ko) | 2003-02-11 | 2005-11-16 | 학교법인 포항공과대학교 | 쿠커비투릴이 결합된 실리카 겔 |
| KR100502286B1 (ko) * | 2003-02-25 | 2005-07-20 | 광주과학기술원 | 쿠쿠비투릴-풀러렌 복합체 |
| KR100545583B1 (ko) | 2003-07-05 | 2006-01-24 | 학교법인 포항공과대학교 | 쿠커비투릴 유도체가 공유결합된 고체 기판 및 이를이용한 바이오칩 |
| KR100499278B1 (ko) | 2003-07-05 | 2005-07-01 | 학교법인 포항공과대학교 | 로텍산 화합물이 공유결합된 고체 기판 및 이를 이용한바이오칩 |
| KR100554156B1 (ko) * | 2003-07-26 | 2006-02-22 | 학교법인 포항공과대학교 | 쿠커비투릴 유도체가 응집되어 형성된 나노 입자, 그 나노입자에 약물이 담지된 약제학적 조성물, 및 이들의 제조방법 |
| CA2537843A1 (en) * | 2003-09-12 | 2005-03-24 | Newsouth Innovations Pty Limited | Method for preparing cucurbiturils |
| WO2005068469A1 (en) * | 2004-01-15 | 2005-07-28 | Newsouth Innovations Pty Limited | Multi-nuclear metal complexes partially encapsulated by cucurbit[7-12]urils |
| KR20050102295A (ko) * | 2004-04-21 | 2005-10-26 | 학교법인 포항공과대학교 | 리포좀 및 그 제조방법 |
| KR100567347B1 (ko) | 2004-04-21 | 2006-04-04 | 학교법인 포항공과대학교 | 쿠커비투릴 유도체를 이용한 고분자 초박막 및 그 제조방법 |
| EP1765313A2 (de) | 2004-06-24 | 2007-03-28 | Novartis Vaccines and Diagnostics, Inc. | Verbindungen als immunstimulatoren |
| KR100687731B1 (ko) | 2005-10-20 | 2007-03-02 | 학교법인 포항공과대학교 | 쿠커비투릴을 이용한 고분자 초박막의 제조방법 |
| KR100750320B1 (ko) | 2006-01-04 | 2007-08-17 | 학교법인 포항공과대학교 | 쿠커비투릴을 포함하는 젤 |
| JO2660B1 (en) | 2006-01-20 | 2012-06-17 | نوفارتيس ايه جي | Pi-3 inhibitors and methods of use |
| TW200808739A (en) | 2006-04-06 | 2008-02-16 | Novartis Vaccines & Diagnostic | Quinazolines for PDK1 inhibition |
| CZ300120B6 (cs) * | 2006-06-20 | 2009-02-11 | Pliva - Lachema A. S. | Farmaceutická kompozice pro injekcní podání |
| JP4693745B2 (ja) * | 2006-10-23 | 2011-06-01 | 独立行政法人科学技術振興機構 | Ｎ−末端にフェニルアラニン残基を有するペプチド化合物の定量方法 |
| JP4762114B2 (ja) * | 2006-11-09 | 2011-08-31 | 独立行政法人科学技術振興機構 | ペプチド化合物ｐｙｙ３−３６の存否の確認方法 |
| KR100922990B1 (ko) * | 2007-11-16 | 2009-10-22 | 광주과학기술원 | 초분자 접근을 통한 수분산형 자외선 차단제의 제조방법 |
| ES2437595T3 (es) | 2007-12-20 | 2014-01-13 | Novartis Ag | Derivados de tiazol usados como inhibidores de la PI 3 quinasa |
| KR100994314B1 (ko) | 2008-11-11 | 2010-11-12 | 광주과학기술원 | 금속-거대고리 화합물 복합체의 합성방법 |
| US8293753B2 (en) | 2009-07-02 | 2012-10-23 | Novartis Ag | Substituted 2-carboxamide cycloamino ureas |
| KR101201473B1 (ko) | 2009-12-29 | 2012-11-15 | 포항공과대학교 산학협력단 | 자기 조립형 약물 및 세포 전달체의 제조 방법 및 이에 의해 제조된 자기 조립형 약물 및 세포 전달체 |
| BR112012019635A2 (pt) | 2010-02-22 | 2016-05-03 | Hoffmann La Roche | compostos inibidores de pirido[3,2-d] pirimidina pi3k delta e métodos de uso |
| AR082418A1 (es) | 2010-08-02 | 2012-12-05 | Novartis Ag | Formas cristalinas de 1-(4-metil-5-[2-(2,2,2-trifluoro-1,1-dimetil-etil)-piridin-4-il]-tiazol-2-il)-amida de 2-amida del acido (s)-pirrolidin-1,2-dicarboxilico |
| CN101935400B (zh) * | 2010-08-23 | 2012-07-25 | 贵州大学 | 一类碱金属-瓜环多层次网状有机框架聚合物及其合成方法和应用 |
| US8987257B2 (en) | 2011-01-31 | 2015-03-24 | Novartis Ag | Heterocyclic derivatives |
| US10988618B2 (en) | 2011-09-23 | 2021-04-27 | Dystar Hilton Davis Corp. | Self-assembled nano-structured particle and methods for preparing |
| WO2013044045A1 (en) | 2011-09-23 | 2013-03-28 | Emerald Hilton Davis, Llc | Self-assembled nano-structure particle and method for preparing |
| MX340452B (es) | 2011-10-28 | 2016-07-08 | Novartis Ag | Novedosos derivados de purina y su uso en el tratamiento de enfermedades. |
| US9101669B2 (en) | 2012-01-31 | 2015-08-11 | Postech Academy-Industry Foundation | Self-assembed conjugate and use thereof |
| KR20150009540A (ko) | 2012-05-16 | 2015-01-26 | 노파르티스 아게 | Pi-3 키나제 억제제에 대한 투여 요법 |
| US9220705B2 (en) | 2013-03-07 | 2015-12-29 | James David Hoeschele | Method of treating colorectal cancer |
| CN103351409B (zh) * | 2013-07-30 | 2016-05-18 | 贵州大学 | 一种六元瓜环基极性多孔材料及其合成方法 |
| KR101714692B1 (ko) * | 2013-12-04 | 2017-03-22 | 기초과학연구원 | 쿠커비투릴-당 복합체 및 이의 제조방법 |
| CN105979947A (zh) | 2013-12-06 | 2016-09-28 | 诺华股份有限公司 | α-同工型选择性磷脂酰肌醇3-激酶抑制剂的剂量方案 |
| CN104117061B (zh) * | 2014-07-09 | 2016-08-17 | 清华大学 | 复合物及其制备方法和应用 |
| RU2018119085A (ru) | 2015-11-02 | 2019-12-04 | Новартис Аг | Схема введения ингибитора фосфатидилинозитол-3-киназы |
| WO2018060833A1 (en) | 2016-09-27 | 2018-04-05 | Novartis Ag | Dosage regimen for alpha-isoform selective phosphatidylinositol 3-kinase inhibitor alpelisib |
| CN107737346A (zh) * | 2017-10-26 | 2018-02-27 | 昆明理工大学 | 一种甲啶铂与葫芦[n]脲的包合物 |
| CN107737345A (zh) * | 2017-10-26 | 2018-02-27 | 昆明理工大学 | 一种奈达铂与葫芦[n]脲的包合物 |
| CN109096341A (zh) * | 2018-09-07 | 2018-12-28 | 中国科学院福建物质结构研究所 | 一种配合物、其制备方法及应用了该配合物的催化剂 |
| CN110452244B (zh) * | 2019-08-31 | 2022-02-18 | 贵州大学 | 一种环己基改性瓜环的合成方法 |
| CN112934004B (zh) * | 2021-01-27 | 2022-10-14 | 天津大学 | 一种葫芦脲/金属离子交联氧化石墨烯复合膜的制备方法及应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5965118A (en) | 1997-04-18 | 1999-10-12 | Access Pharmaceuticals, Inc. | Polymer-platinum compounds |
| EP1094065B1 (de) | 1999-10-21 | 2003-12-17 | Pohang University of Science and Technology Foundation | Verfahren zur Herstellung von Cucurbituril Derivaten |
| KR100400082B1 (ko) * | 1999-10-21 | 2003-09-29 | 학교법인 포항공과대학교 | 쿠커비투릴 유도체의 제조방법 |
-
2001
- 2001-09-18 KR KR10-2001-0057573A patent/KR100484504B1/ko not_active IP Right Cessation
-
2002
- 2002-09-18 US US10/489,968 patent/US7459471B2/en not_active Expired - Fee Related
- 2002-09-18 AU AU2002329097A patent/AU2002329097B2/en not_active Ceased
- 2002-09-18 JP JP2003528825A patent/JP4347693B2/ja not_active Expired - Fee Related
- 2002-09-18 EP EP02765666A patent/EP1430061B1/de not_active Expired - Lifetime
- 2002-09-18 WO PCT/KR2002/001755 patent/WO2003024978A1/en active IP Right Grant
- 2002-09-18 AT AT02765666T patent/ATE532790T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| US20040265237A1 (en) | 2004-12-30 |
| EP1430061A1 (de) | 2004-06-23 |
| KR100484504B1 (ko) | 2005-04-20 |
| KR20030024426A (ko) | 2003-03-26 |
| EP1430061A4 (de) | 2008-02-13 |
| JP2005503415A (ja) | 2005-02-03 |
| JP4347693B2 (ja) | 2009-10-21 |
| EP1430061B1 (de) | 2011-11-09 |
| WO2003024978A1 (en) | 2003-03-27 |
| AU2002329097B2 (en) | 2005-09-15 |
| US7459471B2 (en) | 2008-12-02 |
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