IT1256134B - Sali lipofili contenenti isotopi neutron attivabili e composizioni che li contengono - Google Patents
Sali lipofili contenenti isotopi neutron attivabili e composizioni che li contengonoInfo
- Publication number
- IT1256134B IT1256134B ITMI922090A ITMI922090A IT1256134B IT 1256134 B IT1256134 B IT 1256134B IT MI922090 A ITMI922090 A IT MI922090A IT MI922090 A ITMI922090 A IT MI922090A IT 1256134 B IT1256134 B IT 1256134B
- Authority
- IT
- Italy
- Prior art keywords
- neutron
- lyphophilic
- actuable
- isotopes
- acids
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 229910052692 Dysprosium Inorganic materials 0.000 abstract 1
- 229910052691 Erbium Inorganic materials 0.000 abstract 1
- 229910052688 Gadolinium Inorganic materials 0.000 abstract 1
- 229910052689 Holmium Inorganic materials 0.000 abstract 1
- 229910052765 Lutetium Inorganic materials 0.000 abstract 1
- 229910052772 Samarium Inorganic materials 0.000 abstract 1
- 229910052771 Terbium Inorganic materials 0.000 abstract 1
- 229910052769 Ytterbium Inorganic materials 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 229910052788 barium Inorganic materials 0.000 abstract 1
- DSAJWYNOEDNPEQ-UHFFFAOYSA-N barium atom Chemical compound [Ba] DSAJWYNOEDNPEQ-UHFFFAOYSA-N 0.000 abstract 1
- 239000003613 bile acid Substances 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 150000001841 cholesterols Chemical class 0.000 abstract 1
- KBQHZAAAGSGFKK-UHFFFAOYSA-N dysprosium atom Chemical compound [Dy] KBQHZAAAGSGFKK-UHFFFAOYSA-N 0.000 abstract 1
- UYAHIZSMUZPPFV-UHFFFAOYSA-N erbium Chemical compound [Er] UYAHIZSMUZPPFV-UHFFFAOYSA-N 0.000 abstract 1
- UIWYJDYFSGRHKR-UHFFFAOYSA-N gadolinium atom Chemical compound [Gd] UIWYJDYFSGRHKR-UHFFFAOYSA-N 0.000 abstract 1
- KJZYNXUDTRRSPN-UHFFFAOYSA-N holmium atom Chemical compound [Ho] KJZYNXUDTRRSPN-UHFFFAOYSA-N 0.000 abstract 1
- OHSVLFRHMCKCQY-UHFFFAOYSA-N lutetium atom Chemical compound [Lu] OHSVLFRHMCKCQY-UHFFFAOYSA-N 0.000 abstract 1
- 150000003904 phospholipids Chemical class 0.000 abstract 1
- KZUNJOHGWZRPMI-UHFFFAOYSA-N samarium atom Chemical compound [Sm] KZUNJOHGWZRPMI-UHFFFAOYSA-N 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 235000003441 saturated fatty acids Nutrition 0.000 abstract 1
- 150000004671 saturated fatty acids Chemical class 0.000 abstract 1
- GZCRRIHWUXGPOV-UHFFFAOYSA-N terbium atom Chemical compound [Tb] GZCRRIHWUXGPOV-UHFFFAOYSA-N 0.000 abstract 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 abstract 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 abstract 1
- NAWDYIZEMPQZHO-UHFFFAOYSA-N ytterbium Chemical compound [Yb] NAWDYIZEMPQZHO-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/009—Neutron capture therapy, e.g. using uranium or non-boron material
- A61K41/0095—Boron neutron capture therapy, i.e. BNCT, e.g. using boronated porphyrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Optics & Photonics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Fire-Extinguishing Compositions (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Lubricants (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Sali lipofili costituiti da cationi neutron attivabili scelti nel gruppo comprendente samario, erbio, ytterbio, gadolinio, terbio, holmio, disprosio, lutezio e bario e da anioni lipofili derivanti da acidi grassi saturi e insaturi, acidi biliari, acidi alchilfosforici, fosfolipidi con gruppi acidi, acidi diacilfosfatidici ed acidi colesterolici, procedimento per la loro preparazione e composizioni che li contengono.
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI922090A IT1256134B (it) | 1992-09-09 | 1992-09-09 | Sali lipofili contenenti isotopi neutron attivabili e composizioni che li contengono |
| AT93114313T ATE156114T1 (de) | 1992-09-09 | 1993-09-07 | Neutronenaktivierbare kationen enthaltende lipophile zusammensetzungen |
| EP93114313A EP0587106B1 (en) | 1992-09-09 | 1993-09-07 | Compositions containing lipophilic salts having neutron activable cations |
| DE69312605T DE69312605T2 (de) | 1992-09-09 | 1993-09-07 | Neutronenaktivierbare Kationen enthaltende lipophile Zusammensetzungen |
| ES93114313T ES2108180T3 (es) | 1992-09-09 | 1993-09-07 | Composiciones que contienen sales lipofilicas que tienen cationes activables por neutrones. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI922090A IT1256134B (it) | 1992-09-09 | 1992-09-09 | Sali lipofili contenenti isotopi neutron attivabili e composizioni che li contengono |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI922090A0 ITMI922090A0 (it) | 1992-09-09 |
| ITMI922090A1 ITMI922090A1 (it) | 1994-03-09 |
| IT1256134B true IT1256134B (it) | 1995-11-29 |
Family
ID=11363932
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI922090A IT1256134B (it) | 1992-09-09 | 1992-09-09 | Sali lipofili contenenti isotopi neutron attivabili e composizioni che li contengono |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0587106B1 (it) |
| AT (1) | ATE156114T1 (it) |
| DE (1) | DE69312605T2 (it) |
| ES (1) | ES2108180T3 (it) |
| IT (1) | IT1256134B (it) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9607955D0 (en) * | 1996-04-17 | 1996-06-19 | Tillotts Pharma Ag | Hydrophobic carbomer salt compositions |
| NL1006135C2 (nl) | 1997-05-27 | 1998-12-01 | Academisch Ziekenhuis Utrecht | Inrichting en werkwijze voor het voor toediening gereed maken van radio-actieve geneesmiddelen. |
| US7091192B1 (en) | 1998-07-01 | 2006-08-15 | California Institute Of Technology | Linear cyclodextrin copolymers |
| US6509323B1 (en) | 1998-07-01 | 2003-01-21 | California Institute Of Technology | Linear cyclodextrin copolymers |
| KR101476067B1 (ko) | 2002-09-06 | 2014-12-23 | 인설트 테라페틱스, 인코퍼레이티드 | 공유결합된 치료제 전달을 위한 사이클로덱스트린-기초 중합체 |
| US8124120B2 (en) | 2003-12-22 | 2012-02-28 | Anika Therapeutics, Inc. | Crosslinked hyaluronic acid compositions for tissue augmentation |
| EP1674081A1 (de) * | 2004-12-23 | 2006-06-28 | KTB Tumorforschungsgesellschaft mbH | Herstellung von lipidbasierten Nanopartikeln unter Einsatz einer dualen asymmetrischen Zentrifuge |
| US20080176958A1 (en) | 2007-01-24 | 2008-07-24 | Insert Therapeutics, Inc. | Cyclodextrin-based polymers for therapeutics delivery |
| US20140094432A1 (en) | 2012-10-02 | 2014-04-03 | Cerulean Pharma Inc. | Methods and systems for polymer precipitation and generation of particles |
| CN107049950B (zh) * | 2016-12-29 | 2020-06-26 | 鲁东大学 | 一种环糊精聚合物载药囊泡的制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4831996B1 (it) * | 1969-04-14 | 1973-10-03 | ||
| CA984984A (en) * | 1972-11-24 | 1976-03-02 | Polysar Limited | Halogenated butyl rubber of improved scorch characteristics |
| JPS5345344A (en) * | 1976-10-05 | 1978-04-24 | Akishima Kagaku Kogyo | Liquid one package stabilizer compositions of resins containing halogen |
| SU867919A1 (ru) * | 1980-01-23 | 1981-09-30 | Предприятие П/Я А-3917 | Состав дл термоиндикатора плавлени |
| US4423152A (en) * | 1981-06-08 | 1983-12-27 | York Research Corporation | Effluent detection methods |
| JPS5849307A (ja) * | 1981-09-16 | 1983-03-23 | Pola Chem Ind Inc | 化粧料 |
| JPS59113039A (ja) * | 1982-12-17 | 1984-06-29 | Dainippon Ink & Chem Inc | 樹脂積層物 |
| JPS60116645A (ja) * | 1983-11-30 | 1985-06-24 | Mitsubishi Rayon Co Ltd | カルボン酸ランタニド塩の製造法 |
| EP0261002B1 (fr) * | 1986-09-19 | 1991-09-04 | Rhone-Poulenc Chimie | Utilisation de composition a base de terres rares destinée pour stabiliser les combustibles pour moteurs diesel |
| CN87101021A (zh) * | 1987-04-24 | 1988-11-02 | 上海冶金耀声化工厂 | 稀土金属聚氯乙稀塑料热稳定剂 |
| JPH01179764A (ja) * | 1988-01-11 | 1989-07-17 | Sumitomo Electric Ind Ltd | 窒化アルミニウム焼結体およびその製造方法 |
| JPH06102784B2 (ja) * | 1989-09-08 | 1994-12-14 | 株式会社ジャパンエナジー | 燃焼性に優れた石油コークスの製造方法 |
-
1992
- 1992-09-09 IT ITMI922090A patent/IT1256134B/it active IP Right Grant
-
1993
- 1993-09-07 DE DE69312605T patent/DE69312605T2/de not_active Expired - Fee Related
- 1993-09-07 ES ES93114313T patent/ES2108180T3/es not_active Expired - Lifetime
- 1993-09-07 EP EP93114313A patent/EP0587106B1/en not_active Expired - Lifetime
- 1993-09-07 AT AT93114313T patent/ATE156114T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE156114T1 (de) | 1997-08-15 |
| ES2108180T3 (es) | 1997-12-16 |
| DE69312605T2 (de) | 1998-03-12 |
| EP0587106A3 (en) | 1994-05-25 |
| ITMI922090A1 (it) | 1994-03-09 |
| DE69312605D1 (de) | 1997-09-04 |
| ITMI922090A0 (it) | 1992-09-09 |
| EP0587106A2 (en) | 1994-03-16 |
| EP0587106B1 (en) | 1997-07-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970929 |