CY1114941T1 - Πολυμερη βασιζομενα σε κυκλοδεξτρινη για χορηγηση των θεραπευτικων μεσων που ειναι ομοιοπολικως δεσμευμενα σε αυτα - Google Patents
Πολυμερη βασιζομενα σε κυκλοδεξτρινη για χορηγηση των θεραπευτικων μεσων που ειναι ομοιοπολικως δεσμευμενα σε αυταInfo
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- CY1114941T1 CY1114941T1 CY20131100656T CY131100656T CY1114941T1 CY 1114941 T1 CY1114941 T1 CY 1114941T1 CY 20131100656 T CY20131100656 T CY 20131100656T CY 131100656 T CY131100656 T CY 131100656T CY 1114941 T1 CY1114941 T1 CY 1114941T1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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- A—HUMAN NECESSITIES
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
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Abstract
Η παρούσα εφεύρεση σχετίζεται με νέες συνθέσεις θεραπευτικών κυκλοδεξτρινούχων πολυμερικών ενώσεων σχεδιασμένων ως φορέας για χορήγηση μικρομοριακών θεραπευτικών ουσιών και με φαρμακευτικές συνθέσεις αυτών. Αυτά τα κυκλοδεξτρινούχα πολυμερή βελτιώνουν τη σταθερότητα και διαλυτότητα της φαρμακευτικής ουσίας, και ελαττώνουν την τοξικότητα της μικρομοριακής θεραπευτικής ουσίας όταν χρησιμοποιούνται in vivo. Περαιτέρω, μέσω επιλογής από ποικιλία ομάδων αρθρωτή και συνδετών στοχοποίησης, τα πολυμερή προσφέρουν μεθόδους για ελεγχόμενη χορήγηση των θεραπευτικών μέσων. Η εφεύρεση επίσης σχετίζεται με μεθόδους αγωγής εξεταζόμενων με τις θεραπευτικές συνθέσεις που περιγράφονται στο κείμενο. Η εφεύρεση περαιτέρω σχετίζεται με μεθόδους για πραγματοποίηση φαρμακευτικής επιχειρηματικότητας που περιλαμβάνουν παραγωγή, αδειοδότηση, ή διανομή κιτ περιεχόντων ή σχετιζόμενων με τις πολυμερικές ενώσεις που περιγράφονται στο κείμενο.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
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US40885502P | 2002-09-06 | 2002-09-06 | |
US42283002P | 2002-10-31 | 2002-10-31 | |
US45199803P | 2003-03-04 | 2003-03-04 | |
EP10184884.4A EP2277551B1 (en) | 2002-09-06 | 2003-09-04 | Cyclodextrin-based polymers for delivering the therapeutic agents covalently bound thereto |
Publications (1)
Publication Number | Publication Date |
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CY1114941T1 true CY1114941T1 (el) | 2016-12-14 |
Family
ID=31982363
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20121100157T CY1112362T1 (el) | 2002-09-06 | 2012-02-16 | Πολυμερη βασιζομενα σε κυκλοδεξτρινη για χορηγηση των θεραπευτικων μεσων που ειναι ομοιοπολικως δεσμευμενα σε αυτα |
CY20131100656T CY1114941T1 (el) | 2002-09-06 | 2013-07-31 | Πολυμερη βασιζομενα σε κυκλοδεξτρινη για χορηγηση των θεραπευτικων μεσων που ειναι ομοιοπολικως δεσμευμενα σε αυτα |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
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CY20121100157T CY1112362T1 (el) | 2002-09-06 | 2012-02-16 | Πολυμερη βασιζομενα σε κυκλοδεξτρινη για χορηγηση των θεραπευτικων μεσων που ειναι ομοιοπολικως δεσμευμενα σε αυτα |
Country Status (17)
Country | Link |
---|---|
US (20) | US7270808B2 (el) |
EP (4) | EP2277551B1 (el) |
JP (4) | JP2006502301A (el) |
KR (6) | KR101857900B1 (el) |
CN (2) | CN102516417B (el) |
AT (1) | ATE533513T1 (el) |
AU (2) | AU2003278764C1 (el) |
BR (2) | BR122012021252B8 (el) |
CA (1) | CA2497792C (el) |
CY (2) | CY1112362T1 (el) |
ES (3) | ES2417324T3 (el) |
HK (3) | HK1151467A1 (el) |
IL (2) | IL234716A0 (el) |
MX (2) | MX367615B (el) |
PT (2) | PT1534340E (el) |
TW (2) | TWI366464B (el) |
WO (1) | WO2004022099A2 (el) |
Families Citing this family (214)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8106098B2 (en) * | 1999-08-09 | 2012-01-31 | The General Hospital Corporation | Protein conjugates with a water-soluble biocompatible, biodegradable polymer |
US7141540B2 (en) * | 2001-11-30 | 2006-11-28 | Genta Salus Llc | Cyclodextrin grafted biocompatible amphilphilic polymer and methods of preparation and use thereof |
DE60323936D1 (de) * | 2002-01-14 | 2008-11-20 | Gen Hospital Corp | Bioabbaubare polyketale, verfahren zu ihrer herstellung sowie ihre verwendung |
EP1534269B1 (en) | 2002-07-19 | 2013-10-30 | The General Hospital Corporation | Oxime conjugates and methods for their formation and use |
EP2277551B1 (en) | 2002-09-06 | 2013-05-08 | Cerulean Pharma Inc. | Cyclodextrin-based polymers for delivering the therapeutic agents covalently bound thereto |
BR0315198A (pt) * | 2002-10-09 | 2005-08-30 | Insert Therapeutics Inc | Materiais e composições à base de ciclodextrina e usos relacionados aos mesmos |
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- 2012-07-19 US US13/553,400 patent/US8389499B2/en not_active Expired - Lifetime
- 2012-07-19 US US13/553,376 patent/US8399431B2/en not_active Expired - Lifetime
- 2012-08-10 US US13/572,294 patent/US8680202B2/en not_active Expired - Lifetime
- 2012-08-10 US US13/572,243 patent/US8475781B2/en not_active Expired - Lifetime
- 2012-08-10 US US13/572,283 patent/US8404662B2/en not_active Expired - Lifetime
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2013
- 2013-01-11 US US13/739,896 patent/US8609081B2/en not_active Expired - Lifetime
- 2013-01-11 US US13/739,881 patent/US8580242B2/en not_active Expired - Lifetime
- 2013-01-11 US US13/739,864 patent/US8518388B2/en not_active Expired - Lifetime
- 2013-02-15 US US13/769,019 patent/US8580243B2/en not_active Expired - Lifetime
- 2013-02-15 US US13/769,052 patent/US8580244B2/en not_active Expired - Lifetime
- 2013-02-15 US US13/769,076 patent/US8603454B2/en not_active Expired - Lifetime
- 2013-07-31 CY CY20131100656T patent/CY1114941T1/el unknown
- 2013-10-17 US US14/056,554 patent/US20140044669A1/en not_active Abandoned
- 2013-10-24 US US14/061,868 patent/US9550860B2/en not_active Expired - Lifetime
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2014
- 2014-05-27 JP JP2014108845A patent/JP5934743B2/ja not_active Expired - Lifetime
- 2014-07-21 US US14/336,495 patent/US20150165055A1/en not_active Abandoned
- 2014-09-18 IL IL234716A patent/IL234716A0/en unknown
- 2014-09-18 IL IL234715A patent/IL234715A0/en unknown
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2017
- 2017-03-07 US US15/451,861 patent/US20170369651A1/en not_active Abandoned
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2018
- 2018-10-23 HK HK18113565.8A patent/HK1254600A1/zh unknown
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2021
- 2021-01-08 US US17/144,598 patent/US20210128516A1/en not_active Abandoned
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