GT200100183A - Derivados de quinolina y quinazolina. - Google Patents
Derivados de quinolina y quinazolina.Info
- Publication number
- GT200100183A GT200100183A GT200100183A GT200100183A GT200100183A GT 200100183 A GT200100183 A GT 200100183A GT 200100183 A GT200100183 A GT 200100183A GT 200100183 A GT200100183 A GT 200100183A GT 200100183 A GT200100183 A GT 200100183A
- Authority
- GT
- Guatemala
- Prior art keywords
- quinazolina
- quinolina
- derivatives
- solvatos
- esteres
- Prior art date
Links
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 208000001647 Renal Insufficiency Diseases 0.000 abstract 1
- 206010003246 arthritis Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 201000006370 kidney failure Diseases 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/84—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Abstract
LA PRESENTE INVENCION COMPRENDE COMPUETOS DE FORMULA (I) ASI COMO LAS SALES UTILIZABLES FARMACEUTICAMENTE, SOLVATOS Y ESTERES DEL MISMO DONDE R1, R2, R3, R4, A1, A2 SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. ESTOS COMPUESTOS SE PUEDEN UTILIZAR EN FORMA DE PREPARACIONES FARMACEUTICAS PARA EL TRATAMIENTO O PREVENCION DE ARTRITIS, ENFERMEDADES CARDIOVASCULARES, DIABETES, INSUFICIENCIA RENAL, TRASTORNOS ALIMENTARIOS Y OBESIDAD.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00119262 | 2000-09-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
GT200100183A true GT200100183A (es) | 2002-05-23 |
Family
ID=8169763
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GT200100183A GT200100183A (es) | 2000-09-06 | 2001-09-05 | Derivados de quinolina y quinazolina. |
Country Status (16)
Country | Link |
---|---|
US (2) | US6900226B2 (es) |
EP (1) | EP1318981A2 (es) |
JP (1) | JP2004508357A (es) |
KR (1) | KR100621272B1 (es) |
CN (1) | CN1274676C (es) |
AR (1) | AR030596A1 (es) |
AU (2) | AU1047402A (es) |
BR (1) | BR0113710A (es) |
CA (1) | CA2420703A1 (es) |
GT (1) | GT200100183A (es) |
MX (1) | MXPA03001928A (es) |
PA (1) | PA8528401A1 (es) |
PE (1) | PE20020485A1 (es) |
UY (1) | UY26926A1 (es) |
WO (1) | WO2002020488A2 (es) |
ZA (1) | ZA200301719B (es) |
Families Citing this family (77)
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US8058233B2 (en) * | 2002-01-10 | 2011-11-15 | Oregon Health And Science University | Modification of feeding behavior using PYY and GLP-1 |
ES2304498T3 (es) * | 2002-02-04 | 2008-10-16 | F. Hoffmann-La Roche Ag | Derivados de quinolina como antagonistas de npy. |
CA2478183C (en) | 2002-03-12 | 2010-02-16 | Merck & Co. Inc. | Substituted amides |
US7105526B2 (en) | 2002-06-28 | 2006-09-12 | Banyu Pharmaceuticals Co., Ltd. | Benzimidazole derivatives |
RU2296757C2 (ru) | 2002-07-05 | 2007-04-10 | Ф.Хоффманн-Ля Рош Аг | Производные хиназолина |
MXPA05001328A (es) | 2002-08-07 | 2005-04-28 | Hoffmann La Roche | Derivados de tiazol. |
US7759336B2 (en) * | 2002-12-10 | 2010-07-20 | Ono Pharmaceutical Co., Ltd. | Nitrogen-containing heterocyclic compounds and medicinal use thereof |
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US8283354B2 (en) * | 2004-09-02 | 2012-10-09 | Vertex Pharmaceuticals Incorporated | Quinazolines useful as modulators of ion channels |
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US6787558B2 (en) * | 2001-09-28 | 2004-09-07 | Hoffmann-La Roche Inc. | Quinoline derivatives |
ES2304498T3 (es) * | 2002-02-04 | 2008-10-16 | F. Hoffmann-La Roche Ag | Derivados de quinolina como antagonistas de npy. |
WO2004002960A1 (en) * | 2002-06-27 | 2004-01-08 | Schering Aktiengesellschaft | Substituted quinoline ccr5 receptor antagonists |
RU2296757C2 (ru) * | 2002-07-05 | 2007-04-10 | Ф.Хоффманн-Ля Рош Аг | Производные хиназолина |
-
2001
- 2001-08-27 US US09/939,883 patent/US6900226B2/en not_active Expired - Fee Related
- 2001-08-30 KR KR1020037003252A patent/KR100621272B1/ko not_active IP Right Cessation
- 2001-08-30 CN CNB018134610A patent/CN1274676C/zh not_active Expired - Fee Related
- 2001-08-30 WO PCT/EP2001/010014 patent/WO2002020488A2/en not_active Application Discontinuation
- 2001-08-30 CA CA002420703A patent/CA2420703A1/en not_active Abandoned
- 2001-08-30 BR BR0113710-7A patent/BR0113710A/pt not_active IP Right Cessation
- 2001-08-30 EP EP01978324A patent/EP1318981A2/en not_active Withdrawn
- 2001-08-30 AU AU1047402A patent/AU1047402A/xx active Pending
- 2001-08-30 AU AU2002210474A patent/AU2002210474B2/en not_active Ceased
- 2001-08-30 JP JP2002525110A patent/JP2004508357A/ja active Pending
- 2001-08-30 MX MXPA03001928A patent/MXPA03001928A/es not_active Application Discontinuation
- 2001-09-04 PA PA20018528401A patent/PA8528401A1/es unknown
- 2001-09-04 AR ARP010104191A patent/AR030596A1/es unknown
- 2001-09-05 GT GT200100183A patent/GT200100183A/es unknown
- 2001-09-05 PE PE2001000891A patent/PE20020485A1/es not_active Application Discontinuation
- 2001-09-05 UY UY26926A patent/UY26926A1/es not_active Application Discontinuation
-
2003
- 2003-02-28 ZA ZA200301719A patent/ZA200301719B/en unknown
-
2005
- 2005-04-07 US US11/100,938 patent/US7265125B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2004508357A (ja) | 2004-03-18 |
US20050176698A1 (en) | 2005-08-11 |
US7265125B2 (en) | 2007-09-04 |
AU2002210474B2 (en) | 2006-11-02 |
ZA200301719B (en) | 2004-06-22 |
US6900226B2 (en) | 2005-05-31 |
UY26926A1 (es) | 2002-03-22 |
AU1047402A (en) | 2002-03-22 |
CN1444563A (zh) | 2003-09-24 |
WO2002020488A3 (en) | 2002-05-16 |
AR030596A1 (es) | 2003-08-27 |
KR20030027110A (ko) | 2003-04-03 |
BR0113710A (pt) | 2003-06-03 |
PE20020485A1 (es) | 2002-06-14 |
US20020052356A1 (en) | 2002-05-02 |
CA2420703A1 (en) | 2002-03-14 |
PA8528401A1 (es) | 2002-09-30 |
KR100621272B1 (ko) | 2006-09-13 |
WO2002020488A2 (en) | 2002-03-14 |
CN1274676C (zh) | 2006-09-13 |
EP1318981A2 (en) | 2003-06-18 |
MXPA03001928A (es) | 2003-06-19 |
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