ATE429435T1 - 7h-pyrrolopyrimidinderivate - Google Patents

7h-pyrrolopyrimidinderivate

Info

Publication number
ATE429435T1
ATE429435T1 AT05715376T AT05715376T ATE429435T1 AT E429435 T1 ATE429435 T1 AT E429435T1 AT 05715376 T AT05715376 T AT 05715376T AT 05715376 T AT05715376 T AT 05715376T AT E429435 T1 ATE429435 T1 AT E429435T1
Authority
AT
Austria
Prior art keywords
derivatives
preparation
pharmaceutical compositions
pyrrolopyrimidine derivatives
pyrrolo
Prior art date
Application number
AT05715376T
Other languages
English (en)
Inventor
Giorgio Caravatti
Andrea Vaupel
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE429435T1 publication Critical patent/ATE429435T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT05715376T 2004-02-18 2005-02-17 7h-pyrrolopyrimidinderivate ATE429435T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0403606.7A GB0403606D0 (en) 2004-02-18 2004-02-18 Organic compounds
PCT/EP2005/001635 WO2005077951A2 (en) 2004-02-18 2005-02-17 7h-pyrrolopyrimidine derivatives

Publications (1)

Publication Number Publication Date
ATE429435T1 true ATE429435T1 (de) 2009-05-15

Family

ID=32039961

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05715376T ATE429435T1 (de) 2004-02-18 2005-02-17 7h-pyrrolopyrimidinderivate

Country Status (16)

Country Link
US (1) US7625894B2 (de)
EP (1) EP1718651B1 (de)
JP (1) JP2007523115A (de)
KR (1) KR20060124705A (de)
CN (1) CN1922184A (de)
AT (1) ATE429435T1 (de)
AU (1) AU2005212832B2 (de)
BR (1) BRPI0507811A (de)
CA (1) CA2553889A1 (de)
DE (1) DE602005014087D1 (de)
ES (1) ES2322814T3 (de)
GB (1) GB0403606D0 (de)
PL (1) PL1718651T3 (de)
PT (1) PT1718651E (de)
RU (1) RU2006133264A (de)
WO (1) WO2005077951A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2709202C (en) 2007-12-19 2013-04-23 Amgen Inc. Fused pyridine, pyrimidine and triazine compounds as cell cycle inhibitors
WO2009126584A1 (en) 2008-04-07 2009-10-15 Amgen Inc. Gem-disubstituted and spirocyclic amino pyridines/pyrimidines as cell cycle inhibitors
KR20160035613A (ko) 2011-03-23 2016-03-31 암젠 인크 Cdk 4/6 및 flt3의 융합된 트리사이클릭 이중 저해제
JP6318156B2 (ja) * 2012-09-06 2018-04-25 プレキシコン インコーポレーテッドＰｌｅｘｘｉｋｏｎ Ｉｎｃ． キナーゼをモジュレートするための化合物および方法、ならびにその指標
AR095202A1 (es) * 2013-03-11 2015-09-30 Merck Patent Gmbh Heterociclos como moduladores de la actividad quinasa
WO2014145576A2 (en) 2013-03-15 2014-09-18 Northwestern University Substituted pyrrolo(2,3-d)pyrimidines for the treatment of cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE217873T1 (de) * 1996-01-23 2002-06-15 Novartis Erfind Verwalt Gmbh Pyrrolopyrimidinen und verfahren zu deren herstellung
AU720429B2 (en) * 1996-08-23 2000-06-01 Novartis Ag Substituted pyrrolopyrimidines and processes for their preparation
ATE242245T1 (de) * 1997-03-19 2003-06-15 Basf Ag Pyrrolo(2,3-d)pyrimidine und ihre verwendung als tyrosinkinase-inhibitoren
PA8474101A1 (es) * 1998-06-19 2000-09-29 Pfizer Prod Inc Compuestos de pirrolo [2,3-d] pirimidina
GB0119249D0 (en) 2001-08-07 2001-10-03 Novartis Ag Organic compounds
EP1441736A2 (de) * 2001-10-29 2004-08-04 Novartis AG Verwendung von 7h-pyrrolo[2,3-d]pyrimidinderivaten in der behandlung solider tumore
US7253166B2 (en) * 2003-04-22 2007-08-07 Irm Llc 6-phenyl-7H-pyrrolo[2,3-d]pyrimidine compounds that induce neuronal differentiation in embryonic stem cells
US20050165029A1 (en) 2004-01-13 2005-07-28 Ambit Biosciences Corporation Pyrrolopyrimidine derivatives and analogs and their use in the treatment and prevention of diseases
AR047470A1 (es) * 2004-01-29 2006-01-18 Novartis Ag Derivados de pirrolo-pirimidina utiles para el tratamiento de enfermedades proliferativas,composiciones farmaceuticas que los contienen,y procesos para su preparacion

Also Published As

Publication number Publication date
JP2007523115A (ja) 2007-08-16
PL1718651T3 (pl) 2009-09-30
EP1718651B1 (de) 2009-04-22
US20070135460A1 (en) 2007-06-14
DE602005014087D1 (de) 2009-06-04
CN1922184A (zh) 2007-02-28
AU2005212832A1 (en) 2005-08-25
US7625894B2 (en) 2009-12-01
BRPI0507811A (pt) 2007-07-10
KR20060124705A (ko) 2006-12-05
WO2005077951A3 (en) 2006-03-02
PT1718651E (pt) 2009-07-17
WO2005077951A2 (en) 2005-08-25
AU2005212832B2 (en) 2009-11-05
EP1718651A2 (de) 2006-11-08
CA2553889A1 (en) 2005-08-25
ES2322814T3 (es) 2009-06-29
GB0403606D0 (en) 2004-03-24
RU2006133264A (ru) 2008-04-10

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