ATE429435T1 - 7h-pyrrolopyrimidinderivate - Google Patents

7h-pyrrolopyrimidinderivate

Info

Publication number
ATE429435T1
ATE429435T1 AT05715376T AT05715376T ATE429435T1 AT E429435 T1 ATE429435 T1 AT E429435T1 AT 05715376 T AT05715376 T AT 05715376T AT 05715376 T AT05715376 T AT 05715376T AT E429435 T1 ATE429435 T1 AT E429435T1
Authority
AT
Austria
Prior art keywords
derivatives
preparation
pharmaceutical compositions
pyrrolopyrimidine derivatives
pyrrolo
Prior art date
Application number
AT05715376T
Other languages
English (en)
Inventor
Giorgio Caravatti
Andrea Vaupel
Original Assignee
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Pharma Gmbh filed Critical Novartis Pharma Gmbh
Application granted granted Critical
Publication of ATE429435T1 publication Critical patent/ATE429435T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT05715376T 2004-02-18 2005-02-17 7h-pyrrolopyrimidinderivate ATE429435T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0403606.7A GB0403606D0 (en) 2004-02-18 2004-02-18 Organic compounds
PCT/EP2005/001635 WO2005077951A2 (en) 2004-02-18 2005-02-17 7h-pyrrolopyrimidine derivatives

Publications (1)

Publication Number Publication Date
ATE429435T1 true ATE429435T1 (de) 2009-05-15

Family

ID=32039961

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05715376T ATE429435T1 (de) 2004-02-18 2005-02-17 7h-pyrrolopyrimidinderivate

Country Status (16)

Country Link
US (1) US7625894B2 (de)
EP (1) EP1718651B1 (de)
JP (1) JP2007523115A (de)
KR (1) KR20060124705A (de)
CN (1) CN1922184A (de)
AT (1) ATE429435T1 (de)
AU (1) AU2005212832B2 (de)
BR (1) BRPI0507811A (de)
CA (1) CA2553889A1 (de)
DE (1) DE602005014087D1 (de)
ES (1) ES2322814T3 (de)
GB (1) GB0403606D0 (de)
PL (1) PL1718651T3 (de)
PT (1) PT1718651E (de)
RU (1) RU2006133264A (de)
WO (1) WO2005077951A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009085185A1 (en) 2007-12-19 2009-07-09 Amgen Inc. Fused pyridine, pyrimidine and triazine compounds as cell cycle inhibitors
MX2010010975A (es) 2008-04-07 2010-11-01 Amgen Inc Amino piridinas/pirimidinas gem-disustituidas y espirociclicas como inhibidores de ciclo celular.
PT2688887E (pt) 2011-03-23 2015-07-06 Amgen Inc Inibidores duais tricíclicos fusionados de cdk 4/6 e flt3
AU2013312477B2 (en) * 2012-09-06 2018-05-31 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
KR20150124957A (ko) * 2013-03-11 2015-11-06 메르크 파텐트 게엠베하 키나아제 활성의 조절인자로서 (6-[4-1h-이미다졸-2-일)피페리딘-1-일]피리미딘-4-아민 유도체
WO2014145576A2 (en) 2013-03-15 2014-09-18 Northwestern University Substituted pyrrolo(2,3-d)pyrimidines for the treatment of cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6140317A (en) * 1996-01-23 2000-10-31 Novartis Ag Pyrrolopyrimidines and processes for their preparation
DE69738468T2 (de) * 1996-08-23 2009-01-08 Novartis Ag Substituierte pyrrolopyrimidine und verfahren zu ihrer herstellung
ATE242245T1 (de) * 1997-03-19 2003-06-15 Basf Ag Pyrrolo(2,3-d)pyrimidine und ihre verwendung als tyrosinkinase-inhibitoren
PA8474101A1 (es) * 1998-06-19 2000-09-29 Pfizer Prod Inc Compuestos de pirrolo [2,3-d] pirimidina
GB0119249D0 (en) 2001-08-07 2001-10-03 Novartis Ag Organic compounds
WO2003037897A2 (en) * 2001-10-29 2003-05-08 Novartis Ag Use of 7h-pyrrolo[2,3-d]pyrimidine derivatives in the treatment of solid tumor diseases
WO2004093812A2 (en) * 2003-04-22 2004-11-04 Irm Llc Compounds that induce neuronal differentiation in embryonic stem cells
US20050239806A1 (en) * 2004-01-13 2005-10-27 Ambit Biosciences Corporation Pyrrolopyrimidine derivatives and analogs and their use in the treatment and prevention of diseases
PE20051092A1 (es) * 2004-01-29 2006-01-20 Novartis Ag Derivados de pirrolo-pirimidina utiles para el tratamiento de enfermedades proliferativas

Also Published As

Publication number Publication date
JP2007523115A (ja) 2007-08-16
ES2322814T3 (es) 2009-06-29
US7625894B2 (en) 2009-12-01
PL1718651T3 (pl) 2009-09-30
US20070135460A1 (en) 2007-06-14
CN1922184A (zh) 2007-02-28
AU2005212832A1 (en) 2005-08-25
PT1718651E (pt) 2009-07-17
BRPI0507811A (pt) 2007-07-10
KR20060124705A (ko) 2006-12-05
EP1718651B1 (de) 2009-04-22
DE602005014087D1 (de) 2009-06-04
WO2005077951A3 (en) 2006-03-02
WO2005077951A2 (en) 2005-08-25
GB0403606D0 (en) 2004-03-24
AU2005212832B2 (en) 2009-11-05
EP1718651A2 (de) 2006-11-08
RU2006133264A (ru) 2008-04-10
CA2553889A1 (en) 2005-08-25

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