DK1869038T3 - Substituerede 5,6,7,8-tetrahydro-imidazol[1,2-a]pyridin-2-ylamin-forbindelser og deres anvendelse til fremstilling af lægemidler - Google Patents
Substituerede 5,6,7,8-tetrahydro-imidazol[1,2-a]pyridin-2-ylamin-forbindelser og deres anvendelse til fremstilling af lægemidlerInfo
- Publication number
- DK1869038T3 DK1869038T3 DK06724098T DK06724098T DK1869038T3 DK 1869038 T3 DK1869038 T3 DK 1869038T3 DK 06724098 T DK06724098 T DK 06724098T DK 06724098 T DK06724098 T DK 06724098T DK 1869038 T3 DK1869038 T3 DK 1869038T3
- Authority
- DK
- Denmark
- Prior art keywords
- pyridin
- tetrahydro
- substituted
- imidazole
- drugs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102005016547A DE102005016547A1 (de) | 2005-04-08 | 2005-04-08 | Substituierte 5,6,7,8-Tetrahydro-imidazo(1,2-a)pyridin-2-ylamin-Verbindungen und deren Verwendung zur Herstellung von Arzneimitteln |
PCT/EP2006/003153 WO2006105971A1 (de) | 2005-04-08 | 2006-04-07 | Substituierte 5,6,7,8-tetrahydro-imidazo[1 ,2-a]pyridin-2-ylamin-verbindungen und deren verwendung zur herstellung von arzneimitteln |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1869038T3 true DK1869038T3 (da) | 2009-11-16 |
Family
ID=36646199
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK06724098T DK1869038T3 (da) | 2005-04-08 | 2006-04-07 | Substituerede 5,6,7,8-tetrahydro-imidazol[1,2-a]pyridin-2-ylamin-forbindelser og deres anvendelse til fremstilling af lægemidler |
Country Status (13)
Country | Link |
---|---|
US (1) | US7829568B2 (da) |
EP (1) | EP1869038B1 (da) |
JP (1) | JP5119145B2 (da) |
AT (1) | ATE435864T1 (da) |
CA (1) | CA2602623A1 (da) |
CY (1) | CY1109460T1 (da) |
DE (2) | DE102005016547A1 (da) |
DK (1) | DK1869038T3 (da) |
ES (1) | ES2329828T3 (da) |
PL (1) | PL1869038T3 (da) |
PT (1) | PT1869038E (da) |
SI (1) | SI1869038T1 (da) |
WO (1) | WO2006105971A1 (da) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8623898B2 (en) | 2009-03-19 | 2014-01-07 | Taisho Pharmaceutical Co., Ltd. | Glycine transporter inhibiting substances |
JP2018526337A (ja) * | 2015-07-17 | 2018-09-13 | バイエル・クロップサイエンス・アクチェンゲゼルシャフト | 置換ヘテロアリールカルボン酸ヒドラジドまたはその塩、ならびに植物におけるストレス耐性を増強するためのそれらの使用 |
JP7055378B2 (ja) * | 2015-09-17 | 2022-04-18 | ユニバーシティ・オブ・ノートル・ダム・デュ・ラック | マイコバクテリア感染症に対して有用なベンジルアミン含有複素環化合物及び組成物 |
BR112019003158B1 (pt) | 2016-08-15 | 2022-10-25 | Bayer Cropscience Aktiengesellschaft | Derivados de heterociclo bicíclico condensado, seu uso, formulação agroquímica, e método para controlar pragas animais |
AU2018336171B2 (en) | 2017-09-22 | 2023-01-05 | Jubilant Epipad LLC | Heterocyclic compounds as PAD inhibitors |
IL272667B (en) | 2017-10-18 | 2022-09-01 | Jubilant Epipad LLC | Imidazo-pyridine compounds as pad inhibitors |
KR20200085836A (ko) | 2017-11-06 | 2020-07-15 | 주빌런트 프로델 엘엘씨 | Pd1/pd-l1 활성화 억제제로서의 피리미딘 유도체 |
US11459338B2 (en) | 2017-11-24 | 2022-10-04 | Jubilant Episcribe Llc | Heterocyclic compounds as PRMT5 inhibitors |
KR20200131845A (ko) | 2018-03-13 | 2020-11-24 | 주빌런트 프로델 엘엘씨 | Pd1/pd-l1 상호작용/활성화 억제제로서의 비사이클릭 화합물 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2687675B1 (fr) * | 1992-01-31 | 1997-04-18 | Roussel Uclaf | Nouveaux derives bicycliques de la pyridine, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant. |
RU2002110282A (ru) * | 1999-10-08 | 2003-12-20 | Грюненталь ГмбХ (DE) | Замещенные в 6-членном кольце бициклические производные имидазо-3-иламина |
DE19948434A1 (de) * | 1999-10-08 | 2001-06-07 | Gruenenthal Gmbh | Substanzbibliothek enthaltend bicyclische Imidazo-5-amine und/oder bicyclische Imidazo-3-amine |
WO2001053298A1 (en) * | 2000-01-18 | 2001-07-26 | Neurogen Corporation | Imidazopyridines and related azacyclic derivatives as selective modulators of bradykinin b2 receptors |
DE60120398T2 (de) * | 2000-03-29 | 2007-06-06 | Altana Pharma Ag | Imidazopyridin-8-one |
GB0108770D0 (en) * | 2001-04-06 | 2001-05-30 | Eisai London Res Lab Ltd | Inhibitors |
AU2003267087A1 (en) * | 2002-09-13 | 2004-04-30 | Merck & Co., Inc. | Fused heterobicyclo substituted phenyl metabotropic glutamate-5 modulators |
CA2507026A1 (en) * | 2002-11-22 | 2004-06-10 | Takeda Pharmaceutical Company Limited | Imidazole derivatives, their production and use |
GB0303910D0 (en) * | 2003-02-20 | 2003-03-26 | Merck Sharp & Dohme | Therapeutic agents |
BRPI0409241A (pt) * | 2003-04-10 | 2006-03-28 | Pfizer | compostos bicìclicos como antagonistas do receptor de nr2b, composições farmacêuticas compreendendo os mesmos e seu uso |
-
2005
- 2005-04-08 DE DE102005016547A patent/DE102005016547A1/de not_active Withdrawn
-
2006
- 2006-04-07 PT PT06724098T patent/PT1869038E/pt unknown
- 2006-04-07 DE DE502006004182T patent/DE502006004182D1/de active Active
- 2006-04-07 SI SI200630423T patent/SI1869038T1/sl unknown
- 2006-04-07 WO PCT/EP2006/003153 patent/WO2006105971A1/de not_active Application Discontinuation
- 2006-04-07 PL PL06724098T patent/PL1869038T3/pl unknown
- 2006-04-07 EP EP06724098A patent/EP1869038B1/de not_active Not-in-force
- 2006-04-07 CA CA002602623A patent/CA2602623A1/en not_active Abandoned
- 2006-04-07 DK DK06724098T patent/DK1869038T3/da active
- 2006-04-07 JP JP2008504689A patent/JP5119145B2/ja not_active Expired - Fee Related
- 2006-04-07 ES ES06724098T patent/ES2329828T3/es active Active
- 2006-04-07 AT AT06724098T patent/ATE435864T1/de active
-
2007
- 2007-10-05 US US11/868,273 patent/US7829568B2/en not_active Expired - Fee Related
-
2009
- 2009-09-30 CY CY20091101016T patent/CY1109460T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE502006004182D1 (de) | 2009-08-20 |
ES2329828T3 (es) | 2009-12-01 |
EP1869038A1 (de) | 2007-12-26 |
ATE435864T1 (de) | 2009-07-15 |
PT1869038E (pt) | 2009-10-06 |
EP1869038B1 (de) | 2009-07-08 |
DE102005016547A1 (de) | 2006-10-12 |
SI1869038T1 (sl) | 2009-12-31 |
US20080300256A1 (en) | 2008-12-04 |
US7829568B2 (en) | 2010-11-09 |
CA2602623A1 (en) | 2006-10-12 |
CY1109460T1 (el) | 2014-08-13 |
WO2006105971A1 (de) | 2006-10-12 |
JP5119145B2 (ja) | 2013-01-16 |
PL1869038T3 (pl) | 2009-12-31 |
JP2008536829A (ja) | 2008-09-11 |
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