DE602005014087D1 - 7h-pyrrolopyrimidinderivate - Google Patents

7h-pyrrolopyrimidinderivate

Info

Publication number
DE602005014087D1
DE602005014087D1 DE602005014087T DE602005014087T DE602005014087D1 DE 602005014087 D1 DE602005014087 D1 DE 602005014087D1 DE 602005014087 T DE602005014087 T DE 602005014087T DE 602005014087 T DE602005014087 T DE 602005014087T DE 602005014087 D1 DE602005014087 D1 DE 602005014087D1
Authority
DE
Germany
Prior art keywords
derivatives
preparation
pharmaceutical compositions
pyrrolopyrimidinderivate
pyrrolo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005014087T
Other languages
English (en)
Inventor
Giorgio Caravatti
Andrea Vaupel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of DE602005014087D1 publication Critical patent/DE602005014087D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE602005014087T 2004-02-18 2005-02-17 7h-pyrrolopyrimidinderivate Active DE602005014087D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0403606.7A GB0403606D0 (en) 2004-02-18 2004-02-18 Organic compounds
PCT/EP2005/001635 WO2005077951A2 (en) 2004-02-18 2005-02-17 7h-pyrrolopyrimidine derivatives

Publications (1)

Publication Number Publication Date
DE602005014087D1 true DE602005014087D1 (de) 2009-06-04

Family

ID=32039961

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005014087T Active DE602005014087D1 (de) 2004-02-18 2005-02-17 7h-pyrrolopyrimidinderivate

Country Status (16)

Country Link
US (1) US7625894B2 (de)
EP (1) EP1718651B1 (de)
JP (1) JP2007523115A (de)
KR (1) KR20060124705A (de)
CN (1) CN1922184A (de)
AT (1) ATE429435T1 (de)
AU (1) AU2005212832B2 (de)
BR (1) BRPI0507811A (de)
CA (1) CA2553889A1 (de)
DE (1) DE602005014087D1 (de)
ES (1) ES2322814T3 (de)
GB (1) GB0403606D0 (de)
PL (1) PL1718651T3 (de)
PT (1) PT1718651E (de)
RU (1) RU2006133264A (de)
WO (1) WO2005077951A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009085185A1 (en) 2007-12-19 2009-07-09 Amgen Inc. Fused pyridine, pyrimidine and triazine compounds as cell cycle inhibitors
MX2010010975A (es) 2008-04-07 2010-11-01 Amgen Inc Amino piridinas/pirimidinas gem-disustituidas y espirociclicas como inhibidores de ciclo celular.
KR20160035613A (ko) 2011-03-23 2016-03-31 암젠 인크 Cdk 4/6 및 flt3의 융합된 트리사이클릭 이중 저해제
US10227357B2 (en) 2012-09-06 2019-03-12 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
EP2970201B1 (de) * 2013-03-11 2019-06-19 Merck Patent GmbH 6-[4-(1h-imidazol-2-yl)piperidin-1-yl]pyrimidin-4-amin-verbindungen als modulatoren der kinase aktivität
WO2014145576A2 (en) 2013-03-15 2014-09-18 Northwestern University Substituted pyrrolo(2,3-d)pyrimidines for the treatment of cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2177925T3 (es) * 1996-01-23 2002-12-16 Novartis Ag Pirrolopirimidinas y procedimientos para su preparacion.
ATE384062T1 (de) * 1996-08-23 2008-02-15 Novartis Pharma Gmbh Substituierte pyrrolopyrimidine und verfahren zu ihrer herstellung
ID24653A (id) * 1997-03-19 2000-07-27 Basf Ag Zat-zat terapi
PA8474101A1 (es) 1998-06-19 2000-09-29 Pfizer Prod Inc Compuestos de pirrolo [2,3-d] pirimidina
GB0119249D0 (en) 2001-08-07 2001-10-03 Novartis Ag Organic compounds
JP2005507424A (ja) * 2001-10-29 2005-03-17 ノバルティス アクチエンゲゼルシャフト 固形腫瘍の処置における７Ｈ−ピロロ［２，３−ｄ］ピリミジン誘導体の使用
US7253166B2 (en) * 2003-04-22 2007-08-07 Irm Llc 6-phenyl-7H-pyrrolo[2,3-d]pyrimidine compounds that induce neuronal differentiation in embryonic stem cells
WO2005069865A2 (en) * 2004-01-13 2005-08-04 Ambit Biosciences Corporation Pyrrolopyrimidine derivatives and analogs and their use in the treatment and prevention of diseases
PE20051092A1 (es) * 2004-01-29 2006-01-20 Novartis Ag Derivados de pirrolo-pirimidina utiles para el tratamiento de enfermedades proliferativas

Also Published As

Publication number Publication date
AU2005212832B2 (en) 2009-11-05
BRPI0507811A (pt) 2007-07-10
ES2322814T3 (es) 2009-06-29
WO2005077951A3 (en) 2006-03-02
RU2006133264A (ru) 2008-04-10
JP2007523115A (ja) 2007-08-16
GB0403606D0 (en) 2004-03-24
PT1718651E (pt) 2009-07-17
AU2005212832A1 (en) 2005-08-25
KR20060124705A (ko) 2006-12-05
CN1922184A (zh) 2007-02-28
WO2005077951A2 (en) 2005-08-25
US20070135460A1 (en) 2007-06-14
ATE429435T1 (de) 2009-05-15
PL1718651T3 (pl) 2009-09-30
EP1718651B1 (de) 2009-04-22
EP1718651A2 (de) 2006-11-08
CA2553889A1 (en) 2005-08-25
US7625894B2 (en) 2009-12-01

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Legal Events

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8364 No opposition during term of opposition