SE0004054D0 - N-type calcium channel antagonists for the treatment of pain - Google Patents

N-type calcium channel antagonists for the treatment of pain

Info

Publication number
SE0004054D0
SE0004054D0 SE0004054A SE0004054A SE0004054D0 SE 0004054 D0 SE0004054 D0 SE 0004054D0 SE 0004054 A SE0004054 A SE 0004054A SE 0004054 A SE0004054 A SE 0004054A SE 0004054 D0 SE0004054 D0 SE 0004054D0
Authority
SE
Sweden
Prior art keywords
treatment
pain
sup
calcium channel
type calcium
Prior art date
Application number
SE0004054A
Other languages
English (en)
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0004054A priority Critical patent/SE0004054D0/sv
Publication of SE0004054D0 publication Critical patent/SE0004054D0/sv
Priority to PCT/SE2001/002389 priority patent/WO2002036567A1/en
Priority to JP2002539327A priority patent/JP2004513116A/ja
Priority to AU2002212895A priority patent/AU2002212895A1/en
Priority to US10/415,853 priority patent/US7189714B2/en
Priority to EP01981240A priority patent/EP1339688A1/en
Priority to US11/466,562 priority patent/US7348340B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE0004054A 2000-11-06 2000-11-06 N-type calcium channel antagonists for the treatment of pain SE0004054D0 (sv)

Priority Applications (7)

Application Number Priority Date Filing Date Title
SE0004054A SE0004054D0 (sv) 2000-11-06 2000-11-06 N-type calcium channel antagonists for the treatment of pain
PCT/SE2001/002389 WO2002036567A1 (en) 2000-11-06 2001-10-31 N-type calcium channel antagonists for the treatment of pain
JP2002539327A JP2004513116A (ja) 2000-11-06 2001-10-31 疼痛治療のためのｎ−型カルシウムチャンネル拮抗薬
AU2002212895A AU2002212895A1 (en) 2000-11-06 2001-10-31 N-type calcium channel antagonists for the treatment of pain
US10/415,853 US7189714B2 (en) 2000-11-06 2001-10-31 N-type calcium channel antagonists for the treatment of pain
EP01981240A EP1339688A1 (en) 2000-11-06 2001-10-31 N-type calcium channel antagonists for the treatment of pain
US11/466,562 US7348340B2 (en) 2000-11-06 2006-08-23 N-type calcium channel antagonists for the treatment of pain

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0004054A SE0004054D0 (sv) 2000-11-06 2000-11-06 N-type calcium channel antagonists for the treatment of pain

Publications (1)

Publication Number Publication Date
SE0004054D0 true SE0004054D0 (sv) 2000-11-06

Family

ID=20281714

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0004054A SE0004054D0 (sv) 2000-11-06 2000-11-06 N-type calcium channel antagonists for the treatment of pain

Country Status (6)

Country Link
US (2) US7189714B2 (sv)
EP (1) EP1339688A1 (sv)
JP (1) JP2004513116A (sv)
AU (1) AU2002212895A1 (sv)
SE (1) SE0004054D0 (sv)
WO (1) WO2002036567A1 (sv)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020121638A1 (en) * 2000-06-30 2002-09-05 Vladimir Grushin Electroluminescent iridium compounds with fluorinated phenylpyridines, phenylpyrimidines, and phenylquinolines and devices made with such compounds
US6900226B2 (en) * 2000-09-06 2005-05-31 Hoffman-La Roche Inc. Neuropeptide Y antagonists
DE10316659A1 (de) * 2003-04-11 2004-10-28 Boehringer Ingelheim Pharma Gmbh & Co. Kg Tricyclische Heteroaromatische Verbindungen
WO2005000285A2 (en) * 2003-06-13 2005-01-06 Dynogen Pharmaceuticals, Inc. METHODS OF TREATING NON-INFLAMMATORY GASTROINTESTINAL TRACT DISORDERS USING Cav2.2 SUBUNIT CALCIUM CHANNEL MODULATORS
JP5014994B2 (ja) * 2004-09-02 2012-08-29 バーテックス ファーマシューティカルズ インコーポレイテッド イオンチャネルのモジュレーターとして有用なキナゾリン
US8084260B2 (en) * 2004-11-24 2011-12-27 Applied Biosystems, Llc Spectral calibration method and system for multiple instruments
WO2008014815A1 (en) * 2006-07-31 2008-02-07 Rottapharm S.P.A. Amidine derivatives of 2-heteroaryl-quinazolines and quinolines; potent analgesics and anti-inflammatory agents
AU2010314518B2 (en) 2009-11-07 2016-04-21 Merck Patent Gmbh Heteroarylaminoquinolines as TGF-beta receptor kinase inhibitors
ES2561674T3 (es) 2010-03-23 2016-02-29 Glaxosmithkline Llc Antagonistas de TRPV4
WO2011119693A1 (en) * 2010-03-23 2011-09-29 Glaxosmithkline Llc Trpv4 antagonists
SI2634177T1 (sl) * 2010-10-29 2016-11-30 Clino Ltd. Sonda za slikovno obdelavo tau proteinov
US9873670B2 (en) * 2013-11-22 2018-01-23 University Of Kentucky Research Foundation Arylquinoline and analog compounds and use thereof to treat cancer
WO2023016447A1 (en) * 2021-08-09 2023-02-16 Sironax Ltd. Ferroptosis modulators, preparations, and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2568778A (en) * 1948-05-28 1951-09-25 Sterling Drug Inc Tertiary-aminoalkyl-alpha-arylalpha-(4-quinolyl) acetates and amides and their preparation
US2616889A (en) * 1948-07-05 1952-11-04 Roussel Uclaf Condensation products of the sugars with derivatives of esculetol and process
GB794043A (en) 1955-06-03 1958-04-30 Ici Ltd New quinoline derivatives
US4816588A (en) 1986-09-12 1989-03-28 American Cyanamid Company Method for the preparation of pyridine-2,3-dicarboxylic acids
AU754716B2 (en) * 1998-03-26 2002-11-21 Japan Tobacco Inc. Amide derivatives and nociceptin antagonists
US6184226B1 (en) 1998-08-28 2001-02-06 Scios Inc. Quinazoline derivatives as inhibitors of P-38 α
JP2002534512A (ja) 1999-01-15 2002-10-15 ノボ ノルディスク アクティーゼルスカブ 非ペプチドｇｌｐ−１アゴニスト
US6927214B1 (en) 1999-01-15 2005-08-09 Novo Nordisk A/S Non-peptide GLP-1 agonists

Also Published As

Publication number Publication date
JP2004513116A (ja) 2004-04-30
AU2002212895A1 (en) 2002-05-15
EP1339688A1 (en) 2003-09-03
US7189714B2 (en) 2007-03-13
US20040077644A1 (en) 2004-04-22
US20070129363A1 (en) 2007-06-07
US7348340B2 (en) 2008-03-25
WO2002036567A1 (en) 2002-05-10

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