YU13301A - Muskarinski agonisti i antagonisti - Google Patents

Muskarinski agonisti i antagonisti

Info

Publication number
YU13301A
YU13301A YU13301A YU13301A YU13301A YU 13301 A YU13301 A YU 13301A YU 13301 A YU13301 A YU 13301A YU 13301 A YU13301 A YU 13301A YU 13301 A YU13301 A YU 13301A
Authority
YU
Yugoslavia
Prior art keywords
antagonists
muscarinic agonists
present
compounds
muscarinic
Prior art date
Application number
YU13301A
Other languages
English (en)
Inventor
Gurmit Grewal
Anna Toy-Palmer
Xiong Cai
George Mark Latham
Original Assignee
Ucb S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb S.A. filed Critical Ucb S.A.
Publication of YU13301A publication Critical patent/YU13301A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Predmetni pronalazak obezbedjuje nove smeše i njihov farmaceutski sastav koristan u tretmanu bola. Smeše predmetnog pronalaska su azaadamantani, azanoradamantani i azahomoadamantani.[The present invention provides novel compounds and pharmaceutical compositions thereof useful in the treatment of pain. The compounds of the present invention are azaadamantanes, azanoradamantanes and azahomoadamantanes.
YU13301A 1998-08-18 1999-08-16 Muskarinski agonisti i antagonisti YU13301A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9697798P 1998-08-18 1998-08-18

Publications (1)

Publication Number Publication Date
YU13301A true YU13301A (sh) 2005-06-10

Family

ID=22260061

Family Applications (1)

Application Number Title Priority Date Filing Date
YU13301A YU13301A (sh) 1998-08-18 1999-08-16 Muskarinski agonisti i antagonisti

Country Status (30)

Country Link
US (5) US6093724A (sh)
EP (1) EP1112272B1 (sh)
JP (1) JP2002523416A (sh)
KR (1) KR20010072784A (sh)
CN (1) CN1312812A (sh)
AR (1) AR020199A1 (sh)
AT (1) ATE227724T1 (sh)
AU (1) AU750566B2 (sh)
BG (1) BG105256A (sh)
BR (1) BR9913072A (sh)
CA (1) CA2340946A1 (sh)
CO (1) CO5130018A1 (sh)
DE (1) DE69903961T2 (sh)
EE (1) EE200100096A (sh)
ES (1) ES2191455T3 (sh)
HK (1) HK1038918A1 (sh)
HU (1) HUP0103203A3 (sh)
ID (1) ID27544A (sh)
IL (1) IL141050A0 (sh)
IS (1) IS5827A (sh)
NO (1) NO20010804L (sh)
NZ (1) NZ509762A (sh)
PE (1) PE20000988A1 (sh)
PL (1) PL346247A1 (sh)
RU (1) RU2219179C2 (sh)
SK (1) SK1892001A3 (sh)
TR (1) TR200100462T2 (sh)
WO (1) WO2000011001A1 (sh)
YU (1) YU13301A (sh)
ZA (1) ZA200100978B (sh)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2423789A1 (en) * 2000-10-19 2002-04-25 Pfizer Products Inc. Bridged piperazine derivatives
GB0117950D0 (en) * 2001-02-16 2001-09-19 Aventis Pharma Inc Novel heterocyclic urea derivatives andd their use as dopamine D3 receptor ligands
WO2002094827A1 (en) * 2001-05-23 2002-11-28 Neurosearch A/S Fused tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
US20030064979A1 (en) * 2001-06-29 2003-04-03 Hansen Thomas Kruse Method of inhibiting PTP 1B and /or T-cell PTP and/or other PTPases with an Asp residue at position 48
US6828328B1 (en) * 2002-03-01 2004-12-07 Ucb S.A. Analgesic combination of muscarinic agonists
US7897766B2 (en) * 2005-09-23 2011-03-01 Abbott Laboratories Amino-aza-adamantane derivatives and methods of use
US8314119B2 (en) * 2006-11-06 2012-11-20 Abbvie Inc. Azaadamantane derivatives and methods of use
US8076350B2 (en) 2006-12-22 2011-12-13 Abbott Laboratories Spirocyclic azaadamantane derivatives and methods of use
EP2069346B1 (en) 2007-03-23 2011-12-21 Abbott Laboratories Acetamide and carboxamide derivatives of azaadamantane and methods of use thereof
CA2679876A1 (en) 2007-03-23 2008-10-02 Abbott Laboratories 4-substituted azaadamantane derivatives and methods of use thereof
WO2010145208A1 (en) * 2009-06-19 2010-12-23 Abbott Laboratories Diazahomoadamantane derivatives and methods of use thereof
US10265311B2 (en) 2009-07-22 2019-04-23 PureTech Health LLC Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation
CA2804215C (en) 2009-07-22 2019-10-01 Eric Elenko Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation
US9133123B2 (en) 2010-04-23 2015-09-15 Cytokinetics, Inc. Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use
AR081626A1 (es) 2010-04-23 2012-10-10 Cytokinetics Inc Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos
AR081331A1 (es) 2010-04-23 2012-08-08 Cytokinetics Inc Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
BR112013005434A2 (pt) * 2010-09-23 2016-06-07 Abbott Lab novo mono-hidrato de derivados de aza-adamantano
US8759380B2 (en) 2011-04-22 2014-06-24 Cytokinetics, Inc. Certain heterocycles, compositions thereof, and methods for their use
WO2019126559A1 (en) 2017-12-20 2019-06-27 Vanderbilt University Antagonists of the muscarinic acetylcholine receptor m4
AU2019346626B2 (en) 2018-09-28 2022-06-02 Karuna Therapeutics, Inc. Compositions and methods for treating disorders ameliorated by muscarinic receptor activation

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4739074A (en) * 1986-01-22 1988-04-19 Pennwalt Corporation Adamantane spiro-pyrrolidine derivatives
IE63906B1 (en) * 1987-11-13 1995-06-14 Novo Nordisk As Azabicyclic compounds and their preparation and use
US5527813A (en) * 1990-08-21 1996-06-18 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
WO1992011261A1 (en) * 1990-12-21 1992-07-09 Merck Sharp & Dohme Limited 4-azatricyclo[2.2.1.02,6]heptanes and pharmaceutical compositions
US5955470A (en) * 1991-06-11 1999-09-21 Merrell Pharmaceuticals, Inc. Derivatives of amide analogs of certain methano bridged quinolizines
US5641791A (en) * 1991-08-13 1997-06-24 Novo Nordisk A.S Heterocyclic compounds and their preparation and use
HUP9802534A3 (en) * 1995-11-02 1999-06-28 Neurosearch As Fused tropane-derivatives as neurotransmitter reuptake inhibitors
US5914338A (en) * 1996-04-02 1999-06-22 Novo Nordisk Heterocyclic compounds and their preparation and use
US5986100A (en) * 1998-04-02 1999-11-16 Crooks; Peter Anthony Pharmaceutical compositions and methods for use
US5952339A (en) * 1998-04-02 1999-09-14 Bencherif; Merouane Pharmaceutical compositions and methods of using nicotinic antagonists for treating a condition or disorder characterized by alteration in normal neurotransmitter release
US6057446A (en) * 1998-04-02 2000-05-02 Crooks; Peter Anthony Certain 1-aza-tricyclo [3.3.1-13,7 ] decane compounds

Also Published As

Publication number Publication date
US6555550B1 (en) 2003-04-29
EE200100096A (et) 2002-06-17
EP1112272B1 (en) 2002-11-13
IS5827A (is) 2001-01-26
ZA200100978B (en) 2002-02-05
DE69903961T2 (de) 2003-07-03
HK1038918A1 (zh) 2002-04-04
RU2219179C2 (ru) 2003-12-20
NO20010804D0 (no) 2001-02-16
PL346247A1 (en) 2002-01-28
SK1892001A3 (en) 2001-11-06
EP1112272A1 (en) 2001-07-04
CN1312812A (zh) 2001-09-12
BR9913072A (pt) 2001-05-15
US20020045617A1 (en) 2002-04-18
CA2340946A1 (en) 2000-03-02
AU750566B2 (en) 2002-07-25
JP2002523416A (ja) 2002-07-30
PE20000988A1 (es) 2000-09-30
DE69903961D1 (de) 2002-12-19
HUP0103203A2 (hu) 2002-01-28
US6323194B1 (en) 2001-11-27
BG105256A (en) 2001-11-30
WO2000011001A1 (en) 2000-03-02
CO5130018A1 (es) 2002-02-27
TR200100462T2 (tr) 2001-09-21
AU5775899A (en) 2000-03-14
HUP0103203A3 (en) 2002-10-28
US6423842B1 (en) 2002-07-23
US6093724A (en) 2000-07-25
US6251916B1 (en) 2001-06-26
ES2191455T3 (es) 2003-09-01
NO20010804L (no) 2001-04-11
ATE227724T1 (de) 2002-11-15
NZ509762A (en) 2002-12-20
KR20010072784A (ko) 2001-07-31
ID27544A (id) 2001-04-12
AR020199A1 (es) 2002-05-02
IL141050A0 (en) 2002-02-10

Similar Documents

Publication Publication Date Title
YU13301A (sh) Muskarinski agonisti i antagonisti
DE69905170D1 (en) Thiazolopyrimidinderivate
IL157093A0 (en) 1,2,3,4-tetrahydroisoquinolines derivatives as urotensin ii receptor antagonists
BG64475B1 (bg) Ципразидонови соли
MY133996A (en) Compounds for the treatment of ischemia
IL154981A0 (en) Substituted indoles, pharmaceutical compositions containing such indoles and their use as ppay-y-binding agents
AP2001002187A0 (en) Piperidines as CCR5 modulators.
HK1135333A1 (en) Method of using diketopiperazines and composition containing them
TR200100054T2 (tr) Paroksetin metansülfonat
HK1048990A1 (en) Novel compounds.
ZA979961B (en) 5-HT1F agonists
NZ330667A (en) Use of substituted 2,4-imadazolidinedione compounds as analgesics
HUP0104696A3 (en) Pharmaceutical composition containing 5ht1 receptor agonists and metoclopramide for the treatment of migraine
PL1654253T3 (pl) Podstawione pochodne 3-pirolidynoindolu
GB0111186D0 (en) Novel compounds
BG104916A (en) Calcilytic compounds
SE9802937D0 (sv) Novel compounds
BG105761A (en) Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents
IL144199A0 (en) Novel bretylium compositions and kits, and their use in preventing and treating cardiovascular conditions
PL340459A1 (en) Agonists of 5ht1f
IL128500A (en) SUBSTITUTED 1,2,3,4-TETRAHYDRO-2-DIBENZOFURANAMINES AND 2-AMINOCYCLOHEPTA[b] BENZOFURANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
DK1100824T3 (da) Forbindelser med væksthormonfrigivende egenskaber
BG104914A (en) Paroxetine maleate
YU58600A (sh) Oblik vi 5,6-dihloro-2-(izopropilamino)-1-(beta-l-ribofuranozil)-1h-benzimidazola
BG101849A (en) Bicyclic tachyquinine antagonists, their preparation and use in pharmaceutical compositions