HUP0103203A3 - Azaadamantane derivatives and pharmaceutical compositions thereof - Google Patents
Azaadamantane derivatives and pharmaceutical compositions thereofInfo
- Publication number
- HUP0103203A3 HUP0103203A3 HU0103203A HUP0103203A HUP0103203A3 HU P0103203 A3 HUP0103203 A3 HU P0103203A3 HU 0103203 A HU0103203 A HU 0103203A HU P0103203 A HUP0103203 A HU P0103203A HU P0103203 A3 HUP0103203 A3 HU P0103203A3
- Authority
- HU
- Hungary
- Prior art keywords
- pharmaceutical compositions
- azaadamantane derivatives
- azaadamantane
- derivatives
- pharmaceutical
- Prior art date
Links
- WENISBCJPGSITQ-UHFFFAOYSA-N 1-azatricyclo[3.3.1.13,7]decane Chemical class C1C(C2)CC3CC1CN2C3 WENISBCJPGSITQ-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9697798P | 1998-08-18 | 1998-08-18 | |
PCT/US1999/018570 WO2000011001A1 (en) | 1998-08-18 | 1999-08-16 | Muscarinic agonists and antagonists |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0103203A2 HUP0103203A2 (hu) | 2002-01-28 |
HUP0103203A3 true HUP0103203A3 (en) | 2002-10-28 |
Family
ID=22260061
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0103203A HUP0103203A3 (en) | 1998-08-18 | 1999-08-16 | Azaadamantane derivatives and pharmaceutical compositions thereof |
Country Status (30)
Country | Link |
---|---|
US (5) | US6093724A (hu) |
EP (1) | EP1112272B1 (hu) |
JP (1) | JP2002523416A (hu) |
KR (1) | KR20010072784A (hu) |
CN (1) | CN1312812A (hu) |
AR (1) | AR020199A1 (hu) |
AT (1) | ATE227724T1 (hu) |
AU (1) | AU750566B2 (hu) |
BG (1) | BG105256A (hu) |
BR (1) | BR9913072A (hu) |
CA (1) | CA2340946A1 (hu) |
CO (1) | CO5130018A1 (hu) |
DE (1) | DE69903961T2 (hu) |
EE (1) | EE200100096A (hu) |
ES (1) | ES2191455T3 (hu) |
HK (1) | HK1038918A1 (hu) |
HU (1) | HUP0103203A3 (hu) |
ID (1) | ID27544A (hu) |
IL (1) | IL141050A0 (hu) |
IS (1) | IS5827A (hu) |
NO (1) | NO20010804L (hu) |
NZ (1) | NZ509762A (hu) |
PE (1) | PE20000988A1 (hu) |
PL (1) | PL346247A1 (hu) |
RU (1) | RU2219179C2 (hu) |
SK (1) | SK1892001A3 (hu) |
TR (1) | TR200100462T2 (hu) |
WO (1) | WO2000011001A1 (hu) |
YU (1) | YU13301A (hu) |
ZA (1) | ZA200100978B (hu) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA03003475A (es) * | 2000-10-19 | 2003-07-14 | Pfizer Prod Inc | Derivados puente de piperazina. |
GB0117950D0 (en) * | 2001-02-16 | 2001-09-19 | Aventis Pharma Inc | Novel heterocyclic urea derivatives andd their use as dopamine D3 receptor ligands |
WO2002094827A1 (en) * | 2001-05-23 | 2002-11-28 | Neurosearch A/S | Fused tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
US20030064979A1 (en) * | 2001-06-29 | 2003-04-03 | Hansen Thomas Kruse | Method of inhibiting PTP 1B and /or T-cell PTP and/or other PTPases with an Asp residue at position 48 |
US6828328B1 (en) * | 2002-03-01 | 2004-12-07 | Ucb S.A. | Analgesic combination of muscarinic agonists |
US7897766B2 (en) | 2005-09-23 | 2011-03-01 | Abbott Laboratories | Amino-aza-adamantane derivatives and methods of use |
US8314119B2 (en) | 2006-11-06 | 2012-11-20 | Abbvie Inc. | Azaadamantane derivatives and methods of use |
US8076350B2 (en) * | 2006-12-22 | 2011-12-13 | Abbott Laboratories | Spirocyclic azaadamantane derivatives and methods of use |
ES2391596T3 (es) * | 2007-03-23 | 2012-11-28 | Abbott Laboratories | Derivados de azaadamantano 4-sustituidos y métodos de uso de los mismos |
ES2378116T3 (es) | 2007-03-23 | 2012-04-09 | Abbott Laboratories | Derivados acetamida y carboxamida de azaadamantano y métodos de uso de los mismos |
CN102459268A (zh) * | 2009-06-19 | 2012-05-16 | 雅培制药有限公司 | 二氮杂高金刚烷衍生物和其使用方法 |
HUE044653T2 (hu) | 2009-07-22 | 2019-11-28 | PureTech Health LLC | Készítmények olyan rendellenességek kezelésére, amelyek muszkarin-receptor aktiválással enyhíthetõk |
US10265311B2 (en) | 2009-07-22 | 2019-04-23 | PureTech Health LLC | Methods and compositions for treatment of disorders ameliorated by muscarinic receptor activation |
AR081626A1 (es) | 2010-04-23 | 2012-10-10 | Cytokinetics Inc | Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos |
EP2560488B1 (en) | 2010-04-23 | 2015-10-28 | Cytokinetics, Inc. | Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use |
AR081331A1 (es) | 2010-04-23 | 2012-08-08 | Cytokinetics Inc | Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos |
AU2011305462B2 (en) | 2010-09-23 | 2015-11-26 | Abbvie Bahamas Ltd. | Monohydrate of an azaadamantane derivative |
US8759380B2 (en) | 2011-04-22 | 2014-06-24 | Cytokinetics, Inc. | Certain heterocycles, compositions thereof, and methods for their use |
EP3732163A4 (en) * | 2017-12-20 | 2021-07-14 | Vanderbilt University | MUSCARINIAN ACETYLCHOLINE RECEPTOR ANTAGONISTS M4 |
MX2021003621A (es) | 2018-09-28 | 2022-04-13 | Karuna Therapeutics Inc | Composiciones y metodos para tratar trastornos mejorados por medio de activacion de receptor muscarinico. |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4739074A (en) * | 1986-01-22 | 1988-04-19 | Pennwalt Corporation | Adamantane spiro-pyrrolidine derivatives |
IE63906B1 (en) * | 1987-11-13 | 1995-06-14 | Novo Nordisk As | Azabicyclic compounds and their preparation and use |
US5527813A (en) * | 1990-08-21 | 1996-06-18 | Novo Nordisk A/S | Heterocyclic compounds and their preparation and use |
JPH06502616A (ja) * | 1990-12-21 | 1994-03-24 | メルク シヤープ エンド ドーム リミテツド | 治療用化合物 |
US5955470A (en) * | 1991-06-11 | 1999-09-21 | Merrell Pharmaceuticals, Inc. | Derivatives of amide analogs of certain methano bridged quinolizines |
US5641791A (en) * | 1991-08-13 | 1997-06-24 | Novo Nordisk A.S | Heterocyclic compounds and their preparation and use |
AU702720B2 (en) * | 1995-11-02 | 1999-03-04 | Neurosearch A/S | Fused tropane-derivatives as neurotransmitter reuptake inhibitors |
US5914338A (en) * | 1996-04-02 | 1999-06-22 | Novo Nordisk | Heterocyclic compounds and their preparation and use |
US6057446A (en) * | 1998-04-02 | 2000-05-02 | Crooks; Peter Anthony | Certain 1-aza-tricyclo [3.3.1-13,7 ] decane compounds |
US5952339A (en) * | 1998-04-02 | 1999-09-14 | Bencherif; Merouane | Pharmaceutical compositions and methods of using nicotinic antagonists for treating a condition or disorder characterized by alteration in normal neurotransmitter release |
US5986100A (en) * | 1998-04-02 | 1999-11-16 | Crooks; Peter Anthony | Pharmaceutical compositions and methods for use |
-
1999
- 1999-08-16 WO PCT/US1999/018570 patent/WO2000011001A1/en not_active Application Discontinuation
- 1999-08-16 ID IDW20010377A patent/ID27544A/id unknown
- 1999-08-16 TR TR2001/00462T patent/TR200100462T2/xx unknown
- 1999-08-16 DE DE69903961T patent/DE69903961T2/de not_active Expired - Fee Related
- 1999-08-16 EE EEP200100096A patent/EE200100096A/xx unknown
- 1999-08-16 US US09/375,149 patent/US6093724A/en not_active Expired - Fee Related
- 1999-08-16 AU AU57758/99A patent/AU750566B2/en not_active Ceased
- 1999-08-16 HU HU0103203A patent/HUP0103203A3/hu unknown
- 1999-08-16 CN CN99809775A patent/CN1312812A/zh active Pending
- 1999-08-16 EP EP99945064A patent/EP1112272B1/en not_active Expired - Lifetime
- 1999-08-16 CA CA002340946A patent/CA2340946A1/en not_active Abandoned
- 1999-08-16 RU RU2001107139/04A patent/RU2219179C2/ru not_active IP Right Cessation
- 1999-08-16 SK SK189-2001A patent/SK1892001A3/sk unknown
- 1999-08-16 BR BR9913072-6A patent/BR9913072A/pt not_active IP Right Cessation
- 1999-08-16 YU YU13301A patent/YU13301A/sh unknown
- 1999-08-16 AT AT99945064T patent/ATE227724T1/de not_active IP Right Cessation
- 1999-08-16 IL IL14105099A patent/IL141050A0/xx unknown
- 1999-08-16 NZ NZ509762A patent/NZ509762A/xx unknown
- 1999-08-16 ES ES99945064T patent/ES2191455T3/es not_active Expired - Lifetime
- 1999-08-16 KR KR1020017002128A patent/KR20010072784A/ko not_active Application Discontinuation
- 1999-08-16 JP JP2000566274A patent/JP2002523416A/ja active Pending
- 1999-08-16 PL PL99346247A patent/PL346247A1/xx not_active Application Discontinuation
- 1999-08-17 AR ARP990104100A patent/AR020199A1/es unknown
- 1999-08-18 PE PE1999000838A patent/PE20000988A1/es not_active Application Discontinuation
- 1999-08-18 CO CO99052330A patent/CO5130018A1/es unknown
-
2000
- 2000-05-09 US US09/567,785 patent/US6251916B1/en not_active Expired - Fee Related
- 2000-10-17 US US09/690,494 patent/US6323194B1/en not_active Expired - Fee Related
-
2001
- 2001-01-26 IS IS5827A patent/IS5827A/is unknown
- 2001-02-05 ZA ZA200100978A patent/ZA200100978B/xx unknown
- 2001-02-14 BG BG105256A patent/BG105256A/xx unknown
- 2001-02-16 NO NO20010804A patent/NO20010804L/no not_active Application Discontinuation
- 2001-10-05 US US09/972,415 patent/US6423842B1/en not_active Expired - Fee Related
-
2002
- 2002-01-18 HK HK02100409.3A patent/HK1038918A1/zh unknown
- 2002-03-27 US US10/108,046 patent/US6555550B1/en not_active Expired - Fee Related
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