SK288274B6 - Monoklonálna protilátka proti CTLA-4, spôsob jej výroby, farmaceutická kompozícia, bunková línia, izolovaná nukleová kyselina, hostiteľská bunka, transgénny cicavec a použitie monoklonálnej protilátky - Google Patents

Monoklonálna protilátka proti CTLA-4, spôsob jej výroby, farmaceutická kompozícia, bunková línia, izolovaná nukleová kyselina, hostiteľská bunka, transgénny cicavec a použitie monoklonálnej protilátky Download PDF

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Publication number
SK288274B6
SK288274B6 SK5035-2011A SK50352011A SK288274B6 SK 288274 B6 SK288274 B6 SK 288274B6 SK 50352011 A SK50352011 A SK 50352011A SK 288274 B6 SK288274 B6 SK 288274B6
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SK
Slovakia
Prior art keywords
ctla
antibody
antibodies
human
sequence
Prior art date
Application number
SK5035-2011A
Other languages
English (en)
Slovak (sk)
Inventor
Douglas Charles Hanson
Mark Joseph Neveu
Eileen Elliott Mueller
Jeffrey Herbert Hanke
Steven Christopher Gilman
Geoffrey Davis C.
Jose Ramon Corvalan
Original Assignee
Pfizer Inc.
Amgen Fremont Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc., Amgen Fremont Inc. filed Critical Pfizer Inc.
Publication of SK288274B6 publication Critical patent/SK288274B6/sk

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SK5035-2011A 1998-12-23 1999-12-23 Monoklonálna protilátka proti CTLA-4, spôsob jej výroby, farmaceutická kompozícia, bunková línia, izolovaná nukleová kyselina, hostiteľská bunka, transgénny cicavec a použitie monoklonálnej protilátky SK288274B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11364798P 1998-12-23 1998-12-23
PCT/US1999/030895 WO2000037504A2 (en) 1998-12-23 1999-12-23 Human monoclonal antibodies to ctla-4

Publications (1)

Publication Number Publication Date
SK288274B6 true SK288274B6 (sk) 2015-06-02

Family

ID=22350712

Family Applications (2)

Application Number Title Priority Date Filing Date
SK5035-2011A SK288274B6 (sk) 1998-12-23 1999-12-23 Monoklonálna protilátka proti CTLA-4, spôsob jej výroby, farmaceutická kompozícia, bunková línia, izolovaná nukleová kyselina, hostiteľská bunka, transgénny cicavec a použitie monoklonálnej protilátky
SK914-2001A SK288057B6 (sk) 1998-12-23 1999-12-23 Human monoclonal antibody that binds to CTLA-4, pharmaceutical composition comprising same, cell line that produces antibody, nucleic acid and method for production of human CTLA-4 antibody

Family Applications After (1)

Application Number Title Priority Date Filing Date
SK914-2001A SK288057B6 (sk) 1998-12-23 1999-12-23 Human monoclonal antibody that binds to CTLA-4, pharmaceutical composition comprising same, cell line that produces antibody, nucleic acid and method for production of human CTLA-4 antibody

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EP (3) EP1141028B1 (enExample)
JP (2) JP3793693B2 (enExample)
KR (3) KR100617337B1 (enExample)
CN (1) CN1328571B (enExample)
AP (1) AP1590A (enExample)
AT (1) ATE458008T1 (enExample)
AU (1) AU772676B2 (enExample)
BG (1) BG65899B1 (enExample)
BR (2) BRPI9916853B8 (enExample)
CA (1) CA2356215C (enExample)
CR (2) CR6425A (enExample)
CU (1) CU23292B7 (enExample)
CY (1) CY1121451T1 (enExample)
CZ (2) CZ303703B6 (enExample)
DE (1) DE69942037D1 (enExample)
DK (2) DK1141028T3 (enExample)
EA (1) EA006972B1 (enExample)
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HK (1) HK1041274B (enExample)
HR (2) HRP20010551B1 (enExample)
HU (2) HU1300750D0 (enExample)
ID (1) ID29991A (enExample)
IL (2) IL143797A0 (enExample)
IS (2) IS2798B (enExample)
LT (1) LT2112166T (enExample)
MX (1) MXPA01006422A (enExample)
NO (2) NO332618B1 (enExample)
NZ (1) NZ512553A (enExample)
OA (1) OA11917A (enExample)
PL (2) PL210435B1 (enExample)
PT (2) PT1141028E (enExample)
RS (1) RS51309B (enExample)
SG (2) SG143018A1 (enExample)
SI (2) SI1141028T1 (enExample)
SK (2) SK288274B6 (enExample)
TR (2) TR200200735T2 (enExample)
UA (1) UA76936C2 (enExample)
WO (1) WO2000037504A2 (enExample)
ZA (1) ZA200105742B (enExample)

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