CA2356215C - Human monoclonal antibodies to ctla-4 - Google Patents

Human monoclonal antibodies to ctla-4 Download PDF

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Publication number
CA2356215C
CA2356215C CA2356215A CA2356215A CA2356215C CA 2356215 C CA2356215 C CA 2356215C CA 2356215 A CA2356215 A CA 2356215A CA 2356215 A CA2356215 A CA 2356215A CA 2356215 C CA2356215 C CA 2356215C
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Prior art keywords
amino acid
seq
acid sequence
ser
antibody
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Expired - Lifetime
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CA2356215A
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English (en)
French (fr)
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CA2356215A1 (en
Inventor
Douglas Charles Hanson
Mark Joseph Neveu
Eileen Elliott Mueller
Jeffrey Herbert Hanke
Steven Christopher Gilman
C. Geoffrey Davis
Jose Ramon Corvalan
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Individual
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Pfizer Corp SRL
Amgen Fremont Inc
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Publication date
Application filed by Pfizer Corp SRL, Amgen Fremont Inc filed Critical Pfizer Corp SRL
Priority to CA002619682A priority Critical patent/CA2619682A1/en
Publication of CA2356215A1 publication Critical patent/CA2356215A1/en
Application granted granted Critical
Publication of CA2356215C publication Critical patent/CA2356215C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA2356215A 1998-12-23 1999-12-23 Human monoclonal antibodies to ctla-4 Expired - Lifetime CA2356215C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002619682A CA2619682A1 (en) 1998-12-23 1999-12-23 Human monoclonal antibodies to ctla-4

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11364798P 1998-12-23 1998-12-23
US60/113,647 1998-12-23
PCT/US1999/030895 WO2000037504A2 (en) 1998-12-23 1999-12-23 Human monoclonal antibodies to ctla-4

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA002619682A Division CA2619682A1 (en) 1998-12-23 1999-12-23 Human monoclonal antibodies to ctla-4

Publications (2)

Publication Number Publication Date
CA2356215A1 CA2356215A1 (en) 2000-06-29
CA2356215C true CA2356215C (en) 2015-11-24

Family

ID=22350712

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2356215A Expired - Lifetime CA2356215C (en) 1998-12-23 1999-12-23 Human monoclonal antibodies to ctla-4

Country Status (41)

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EP (3) EP1141028B1 (enExample)
JP (2) JP3793693B2 (enExample)
KR (3) KR100617337B1 (enExample)
CN (1) CN1328571B (enExample)
AP (1) AP1590A (enExample)
AT (1) ATE458008T1 (enExample)
AU (1) AU772676B2 (enExample)
BG (1) BG65899B1 (enExample)
BR (2) BRPI9916853B8 (enExample)
CA (1) CA2356215C (enExample)
CR (2) CR6425A (enExample)
CU (1) CU23292B7 (enExample)
CY (1) CY1121451T1 (enExample)
CZ (2) CZ302706B6 (enExample)
DE (1) DE69942037D1 (enExample)
DK (2) DK2112166T3 (enExample)
EA (1) EA006972B1 (enExample)
EE (1) EE05483B1 (enExample)
ES (2) ES2706547T3 (enExample)
GE (1) GEP20053594B (enExample)
HK (1) HK1041274B (enExample)
HR (2) HRP20010551B1 (enExample)
HU (2) HU229566B1 (enExample)
ID (1) ID29991A (enExample)
IL (2) IL143797A0 (enExample)
IS (2) IS2798B (enExample)
LT (1) LT2112166T (enExample)
MX (1) MXPA01006422A (enExample)
NO (2) NO332618B1 (enExample)
NZ (1) NZ512553A (enExample)
OA (1) OA11917A (enExample)
PL (2) PL214003B1 (enExample)
PT (2) PT2112166T (enExample)
RS (1) RS51309B (enExample)
SG (2) SG143018A1 (enExample)
SI (2) SI2112166T1 (enExample)
SK (2) SK288057B6 (enExample)
TR (2) TR200200735T2 (enExample)
UA (1) UA76936C2 (enExample)
WO (1) WO2000037504A2 (enExample)
ZA (1) ZA200105742B (enExample)

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* Cited by examiner, † Cited by third party
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