EP0092918B1
(en)
|
1982-04-22 |
1988-10-19 |
Imperial Chemical Industries Plc |
Continuous release formulations
|
GB8308235D0
(en)
|
1983-03-25 |
1983-05-05 |
Celltech Ltd |
Polypeptides
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
US5807715A
(en)
|
1984-08-27 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
|
US5128326A
(en)
|
1984-12-06 |
1992-07-07 |
Biomatrix, Inc. |
Drug delivery systems based on hyaluronans derivatives thereof and their salts and methods of producing same
|
DE3590766C2
(en)
|
1985-03-30 |
1991-01-10 |
Marc Genf/Geneve Ch Ballivet |
|
US5618920A
(en)
|
1985-11-01 |
1997-04-08 |
Xoma Corporation |
Modular assembly of antibody genes, antibodies prepared thereby and use
|
DE3600905A1
(en)
|
1986-01-15 |
1987-07-16 |
Ant Nachrichtentech |
METHOD FOR DECODING BINARY SIGNALS AND VITERBI DECODERS AND APPLICATIONS
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
US5763192A
(en)
|
1986-11-20 |
1998-06-09 |
Ixsys, Incorporated |
Process for obtaining DNA, RNA, peptides, polypeptides, or protein, by recombinant DNA technique
|
DE3883899T3
(en)
|
1987-03-18 |
1999-04-22 |
Sb2 Inc |
CHANGED ANTIBODIES.
|
US5258498A
(en)
|
1987-05-21 |
1993-11-02 |
Creative Biomolecules, Inc. |
Polypeptide linkers for production of biosynthetic proteins
|
US4880078A
(en)
|
1987-06-29 |
1989-11-14 |
Honda Giken Kogyo Kabushiki Kaisha |
Exhaust muffler
|
JP3771253B2
(en)
|
1988-09-02 |
2006-04-26 |
ダイアックス コープ. |
Generation and selection of novel binding proteins
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
AU634186B2
(en)
|
1988-11-11 |
1993-02-18 |
Medical Research Council |
Single domain ligands, receptors comprising said ligands, methods for their production, and use of said ligands and receptors
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
EP0478627A4
(en)
|
1989-05-16 |
1992-08-19 |
William D. Huse |
Co-expression of heteromeric receptors
|
CA2016842A1
(en)
|
1989-05-16 |
1990-11-16 |
Richard A. Lerner |
Method for tapping the immunological repertoire
|
CA2016841C
(en)
|
1989-05-16 |
1999-09-21 |
William D. Huse |
A method for producing polymers having a preselected activity
|
AU6430190A
(en)
|
1989-10-10 |
1991-05-16 |
Pitman-Moore, Inc. |
Sustained release composition for macromolecular proteins
|
JP2571874B2
(en)
|
1989-11-06 |
1997-01-16 |
アルカーメス コントロールド セラピューティクス,インコーポレイテッド |
Protein microsphere composition
|
GB8928874D0
(en)
|
1989-12-21 |
1990-02-28 |
Celltech Ltd |
Humanised antibodies
|
WO1991010737A1
(en)
|
1990-01-11 |
1991-07-25 |
Molecular Affinities Corporation |
Production of antibodies using gene libraries
|
US5780225A
(en)
|
1990-01-12 |
1998-07-14 |
Stratagene |
Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules
|
CA2050918A1
(en)
|
1990-01-12 |
1991-07-13 |
Raju Kucherlapati |
Generation of xenogeneic antibodies
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
US5427908A
(en)
|
1990-05-01 |
1995-06-27 |
Affymax Technologies N.V. |
Recombinant library screening methods
|
ES2139598T3
(en)
|
1990-07-10 |
2000-02-16 |
Medical Res Council |
PROCEDURES FOR THE PRODUCTION OF SPECIFIC UNION COUPLE MEMBERS.
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
EP0542810A1
(en)
|
1990-08-02 |
1993-05-26 |
B.R. Centre Limited |
Methods for the production of proteins with a desired function
|
US5698426A
(en)
|
1990-09-28 |
1997-12-16 |
Ixsys, Incorporated |
Surface expression libraries of heteromeric receptors
|
DE69129154T2
(en)
|
1990-12-03 |
1998-08-20 |
Genentech Inc |
METHOD FOR ENRICHING PROTEIN VARIANTS WITH CHANGED BINDING PROPERTIES
|
EP1820858B1
(en)
|
1991-03-01 |
2009-08-12 |
Dyax Corporation |
Chimeric protein comprising micro-protein having two or more disulfide bonds and embodiments thereof
|
AU662148B2
(en)
|
1991-04-10 |
1995-08-24 |
Scripps Research Institute, The |
Heterodimeric receptor libraries using phagemids
|
ATE221379T1
(en)
|
1991-05-01 |
2002-08-15 |
Jackson H M Found Military Med |
METHOD FOR TREATING INFECTIOUS RESPIRATORY DISEASES
|
EP0519596B1
(en)
|
1991-05-17 |
2005-02-23 |
Merck & Co. Inc. |
A method for reducing the immunogenicity of antibody variable domains
|
WO1992022324A1
(en)
|
1991-06-14 |
1992-12-23 |
Xoma Corporation |
Microbially-produced antibody fragments and their conjugates
|
DE4122599C2
(en)
|
1991-07-08 |
1993-11-11 |
Deutsches Krebsforsch |
Phagemid for screening antibodies
|
ES2136092T3
(en)
|
1991-09-23 |
1999-11-16 |
Medical Res Council |
PROCEDURES FOR THE PRODUCTION OF HUMANIZED ANTIBODIES.
|
WO1993011236A1
(en)
|
1991-12-02 |
1993-06-10 |
Medical Research Council |
Production of anti-self antibodies from antibody segment repertoires and displayed on phage
|
CA2103887C
(en)
|
1991-12-13 |
2005-08-30 |
Gary M. Studnicka |
Methods and materials for preparation of modified antibody variable domains and therapeutic uses thereof
|
US5714350A
(en)
|
1992-03-09 |
1998-02-03 |
Protein Design Labs, Inc. |
Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region
|
US5912015A
(en)
|
1992-03-12 |
1999-06-15 |
Alkermes Controlled Therapeutics, Inc. |
Modulated release from biocompatible polymers
|
US5733743A
(en)
|
1992-03-24 |
1998-03-31 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
ATE381614T1
(en)
|
1992-07-24 |
2008-01-15 |
Amgen Fremont Inc |
FORMATION OF XENOGENE ANTIBODIES
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
US5934272A
(en)
|
1993-01-29 |
1999-08-10 |
Aradigm Corporation |
Device and method of creating aerosolized mist of respiratory drug
|
JPH09506262A
(en)
|
1993-12-08 |
1997-06-24 |
ジェンザイム・コーポレイション |
Method for producing specific antibody
|
DE69531148T2
(en)
|
1994-01-31 |
2004-04-29 |
Trustees Of Boston University, Boston |
LIBRARIES MADE OF POLYCLONAL ANTIBODIES
|
US5516637A
(en)
|
1994-06-10 |
1996-05-14 |
Dade International Inc. |
Method involving display of protein binding pairs on the surface of bacterial pili and bacteriophage
|
EP0805678B1
(en)
|
1995-01-05 |
2003-10-29 |
THE BOARD OF REGENTS acting for and on behalf of THE UNIVERSITY OF MICHIGAN |
Surface-modified nanoparticles and method of making and using same
|
US6091001A
(en)
|
1995-03-29 |
2000-07-18 |
Abgenix, Inc. |
Production of antibodies using Cre-mediated site-specific recombination
|
US6130364A
(en)
|
1995-03-29 |
2000-10-10 |
Abgenix, Inc. |
Production of antibodies using Cre-mediated site-specific recombination
|
US6019968A
(en)
|
1995-04-14 |
2000-02-01 |
Inhale Therapeutic Systems, Inc. |
Dispersible antibody compositions and methods for their preparation and use
|
KR100479146B1
(en)
|
1995-04-21 |
2005-05-16 |
셀 제네시스, 인코포레이티드 |
Generation of Large Genomic DNA Deletions
|
KR100654645B1
(en)
|
1995-04-27 |
2007-04-04 |
아브게닉스, 인크. |
Human Antibodies from Immunized Genomous
|
EP0823941A4
(en)
|
1995-04-28 |
2001-09-19 |
Abgenix Inc |
Human antibodies derived from immunized xenomice
|
US6127977A
(en)
|
1996-11-08 |
2000-10-03 |
Cohen; Nathan |
Microstrip patch antenna with fractal structure
|
US5916597A
(en)
|
1995-08-31 |
1999-06-29 |
Alkermes Controlled Therapeutics, Inc. |
Composition and method using solid-phase particles for sustained in vivo release of a biologically active agent
|
JP2978435B2
(en)
|
1996-01-24 |
1999-11-15 |
チッソ株式会社 |
Method for producing acryloxypropyl silane
|
CZ292465B6
(en)
|
1996-02-09 |
2003-09-17 |
Abbott Laboratories (Bermuda) Ltd. |
Human antibodies that bind to human TNF alpha
|
ATE508733T1
(en)
|
1996-03-04 |
2011-05-15 |
Penn State Res Found |
MATERIALS AND METHODS FOR INCREASE CELLULAR INTERNALIZATION
|
US5714352A
(en)
|
1996-03-20 |
1998-02-03 |
Xenotech Incorporated |
Directed switch-mediated DNA recombination
|
US5855913A
(en)
|
1997-01-16 |
1999-01-05 |
Massachusetts Instite Of Technology |
Particles incorporating surfactants for pulmonary drug delivery
|
US5874064A
(en)
|
1996-05-24 |
1999-02-23 |
Massachusetts Institute Of Technology |
Aerodynamically light particles for pulmonary drug delivery
|
US5985309A
(en)
|
1996-05-24 |
1999-11-16 |
Massachusetts Institute Of Technology |
Preparation of particles for inhalation
|
US6699658B1
(en)
|
1996-05-31 |
2004-03-02 |
Board Of Trustees Of The University Of Illinois |
Yeast cell surface display of proteins and uses thereof
|
US5916771A
(en)
|
1996-10-11 |
1999-06-29 |
Abgenix, Inc. |
Production of a multimeric protein by cell fusion method
|
ATE549918T1
(en)
|
1996-12-03 |
2012-04-15 |
Amgen Fremont Inc |
HUMAN ANTIBODIES THAT EXPRESSLY BIND HUMAN TNF ALPHA
|
DE69732306T2
(en)
|
1997-01-16 |
2006-01-12 |
Massachusetts Institute Of Technology, Cambridge |
PREPARATION OF PARTICLE MEDICINES FOR INHALATION
|
DE69835143T2
(en)
|
1997-01-21 |
2007-06-06 |
The General Hospital Corp., Boston |
SELECTION OF PROTEINS BY THE RNA PROTEIN FUSIONS
|
US6235883B1
(en)
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
US5989463A
(en)
|
1997-09-24 |
1999-11-23 |
Alkermes Controlled Therapeutics, Inc. |
Methods for fabricating polymer-based controlled release devices
|
SE512663C2
(en)
|
1997-10-23 |
2000-04-17 |
Biogram Ab |
Active substance encapsulation process in a biodegradable polymer
|
WO1999045031A2
(en)
|
1998-03-03 |
1999-09-10 |
Abgenix, Inc. |
Cd147 binding molecules as therapeutics
|
US20020029391A1
(en)
|
1998-04-15 |
2002-03-07 |
Claude Geoffrey Davis |
Epitope-driven human antibody production and gene expression profiling
|
DE69942021D1
(en)
|
1998-04-20 |
2010-04-01 |
Glycart Biotechnology Ag |
GLYCOSYLATION ENGINEERING OF ANTIBODIES TO IMPROVE ANTIBODY-DEPENDENT CELL-EMITTED CYTOTOXICITY
|
DE69907456T2
(en)
|
1998-06-24 |
2004-03-25 |
Advanced Inhalation Research, Inc., Cambridge |
LARGE POROUS PARTICLES SURROUNDERED BY AN INHALER
|
AU770555B2
(en)
|
1998-08-17 |
2004-02-26 |
Abgenix, Inc. |
Generation of modified molecules with increased serum half-lives
|
CN1328571B
(en)
|
1998-12-23 |
2016-08-31 |
辉瑞大药厂 |
The human monoclonal antibodies of anti-CTLA-4
|
DK2168984T3
(en)
|
1999-03-25 |
2012-12-10 |
Abbott Gmbh & Co Kg |
Human antibodies that bind human IL-12 and methods for its production
|
DK2270147T4
(en)
|
1999-04-09 |
2020-08-31 |
Kyowa Kirin Co Ltd |
METHOD OF MONITORING THE ACTIVITY OF IMMUNOLOGICAL FUNCTIONAL MOLECULE
|
AU2001259432B2
(en)
|
2000-05-03 |
2005-04-21 |
Amgen Inc. |
Modified peptides, comprising an FC domain, as therapeutic agents
|
US7449308B2
(en)
|
2000-06-28 |
2008-11-11 |
Glycofi, Inc. |
Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
|
DK1297172T3
(en)
|
2000-06-28 |
2006-02-13 |
Glycofi Inc |
Methods for Generating Modified Glucoproteins
|
NZ526720A
(en)
|
2000-12-28 |
2007-11-30 |
Altus Pharmaceuticals Inc |
Crystallisation of whole antibodies or fragments thereof, on a large scale and a process allowing an alternative route for delivery of therapeutic antibodies
|
US20040192898A1
(en)
|
2001-08-17 |
2004-09-30 |
Jia Audrey Yunhua |
Anti-abeta antibodies
|
DE60232672D1
(en)
|
2001-10-01 |
2009-07-30 |
Dyax Corp |
MULTILACKED EUKARYONTIC DISPLAY VECTORS AND THEIR USES
|
KR100988949B1
(en)
|
2001-10-25 |
2010-10-20 |
제넨테크, 인크. |
Glycoprotein compositions
|
PT2177620E
(en)
|
2003-03-05 |
2015-02-16 |
Halozyme Inc |
Soluble hyaluronidase glycoprotein (shasegp), process for preparing the same, uses and pharmaceutical compositions comprising thereof
|
US20060104968A1
(en)
|
2003-03-05 |
2006-05-18 |
Halozyme, Inc. |
Soluble glycosaminoglycanases and methods of preparing and using soluble glycosaminogly ycanases
|
GB0407315D0
(en)
*
|
2003-07-15 |
2004-05-05 |
Cambridge Antibody Tech |
Human antibody molecules
|
JP4063213B2
(en)
|
2003-12-09 |
2008-03-19 |
カシオ計算機株式会社 |
LIGHT SOURCE DEVICE AND PROJECTOR HAVING THE SAME
|
JP2007535317A
(en)
|
2004-04-15 |
2007-12-06 |
グライコフィ, インコーポレイテッド |
Production of galactosylated glycoproteins in lower eukaryotes
|
AR049390A1
(en)
|
2004-06-09 |
2006-07-26 |
Wyeth Corp |
ANTIBODIES AGAINST HUMAN INTERLEUQUINE-13 AND USES OF THE SAME
|
CA2615983A1
(en)
|
2005-07-21 |
2007-02-01 |
Abbott Laboratories |
Multiple gene expression including sorf constructs and methods with polyproteins, pro-proteins, and proteolysis
|
GB2430883B
(en)
*
|
2005-09-30 |
2008-03-19 |
Cambridge Antibody Tech |
Interleukin-13 antibody composition
|
US7915338B2
(en)
|
2005-12-28 |
2011-03-29 |
3M Innovative Properties Company |
Adhesive with alkanoate blend
|
SG10201508485UA
(en)
*
|
2006-09-08 |
2015-11-27 |
Abbvie Bahamas Ltd |
Interleukin - 13 binding proteins
|
PE20081610A1
(en)
*
|
2007-01-09 |
2008-12-09 |
Wyeth Corp |
FORMULATIONS OF ANTI-IL-13 ANTIBODIES AND USES OF THEM
|
US20090068195A1
(en)
*
|
2007-04-23 |
2009-03-12 |
Wyeth |
Methods and compositions for treating and monitoring treatment of il-13-associated disorders
|
CA2711984A1
(en)
*
|
2008-01-15 |
2009-07-23 |
Abbott Gmbh & Co. Kg |
Powdered protein compositions and methods of making same
|
JP5470817B2
(en)
|
2008-03-10 |
2014-04-16 |
日産自動車株式会社 |
Battery electrode, battery using the same, and manufacturing method thereof
|
US20100233079A1
(en)
*
|
2008-12-04 |
2010-09-16 |
Abbott Laboratories |
Dual Variable Domain Immunoglobulins and Uses Thereof
|
MX2012003138A
(en)
*
|
2009-09-14 |
2012-07-04 |
Abbott Lab Y Abbott Gmbh & Co Kg |
Methods for treating psoriasis.
|
KR20140061403A
(en)
|
2011-07-13 |
2014-05-21 |
애브비 인코포레이티드 |
Methods and compositions for treating asthma using anti-il-13 antibodies
|
JP6136279B2
(en)
|
2013-01-15 |
2017-05-31 |
株式会社ジェイテクト |
Rolling bearing device
|
TWI503850B
(en)
|
2013-03-22 |
2015-10-11 |
Polytronics Technology Corp |
Over-current protection device
|
TWI510996B
(en)
|
2013-10-03 |
2015-12-01 |
Acer Inc |
Methods for controlling a touch panel and portable computers using the same
|
US9816280B1
(en)
|
2016-11-02 |
2017-11-14 |
Matthew Reitnauer |
Portable floor
|