RU2005125645A - Производное 2-оксо-1-пирролидина и его применение - Google Patents

Производное 2-оксо-1-пирролидина и его применение Download PDF

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RU2005125645A
RU2005125645A RU2005125645/04A RU2005125645A RU2005125645A RU 2005125645 A RU2005125645 A RU 2005125645A RU 2005125645/04 A RU2005125645/04 A RU 2005125645/04A RU 2005125645 A RU2005125645 A RU 2005125645A RU 2005125645 A RU2005125645 A RU 2005125645A
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disease
sup
pharmaceutically acceptable
oxo
cocaine
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RU2005125645/04A
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Эдмон ДИФФЕРДЭН (BE)
Эдмон ДИФФЕРДЭН
Бенуа КЕНДА (BE)
Бенуа Кенда
Бенедикт ЛЯЛЛЕМЭН (BE)
Бенедикт ЛЯЛЛЕМЭН
Ален МАТАНЬ (BE)
Ален МАТАНЬ
Филипп МИШЕЛЬ (BE)
Филипп Мишель
Патрик ПАЗО (BE)
Патрик ПАЗО
Патрис ТАЛАГА (BE)
Патрис ТАЛАГА
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Юсиби, С.А. (Be)
ЮСиБи, С.А.
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Application filed by Юсиби, С.А. (Be), ЮСиБи, С.А. filed Critical Юсиби, С.А. (Be)
Publication of RU2005125645A publication Critical patent/RU2005125645A/ru

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Claims (4)

1. (4R) и (4S) диастериозомеры (2S)-2-[2-оксо-4-пропилпирролидинил]бутанамида или их фармацевтически приемлемые соли.
2. Фармацевтическая композиция, содержащая эффективное количество соединения по п.1 и фармацевтически приемлемый разбавитель или носитель.
3. Способ лечения эпилепсии, эпилептогенеза, апоплексического удара и конвульсий, других неврологических заболеваний, включая биполярные заболевания, манию, депрессию, беспокойство, мигрень, тригеминальную и другую невралгию, хроническую боль, невропатическую боль, церебральную ишемию, сердечную аритмию, миотонию, кокаиновую зависимость, паралич, миоклонию, существенное сотрясение и другие расстройства движения, неонатальный церебральный паралич, амиотрофный латеральный склероз, спастичность, болезнь Паркинсона и другие дегенеративные заболевания, бронхиальной астмы, астматического состояния и аллергического бронхита, астматического синдрома, бронхиальной гиперреактивности и бронхоспастических синдромов также как и аллергического и вазомоторного ринита и риноконъюктивита, включающий введение млекопитающему, нуждающемуся в таком лечении, соединения по п.1.
4. Способ по п.3, при котором болезнь представляет собой эпилепсию, невропатическую боль, биполярные заболевания или мигрень.
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