LV15614A - 2-(2-okso-3-pirolin-1-il)acetamīdi kā pretkrampju līdzekļi - Google Patents
2-(2-okso-3-pirolin-1-il)acetamīdi kā pretkrampju līdzekļiInfo
- Publication number
- LV15614A LV15614A LVP-20-49A LVP2020000049A LV15614A LV 15614 A LV15614 A LV 15614A LV P2020000049 A LVP2020000049 A LV P2020000049A LV 15614 A LV15614 A LV 15614A
- Authority
- LV
- Latvia
- Prior art keywords
- anticonvulsants
- pyrolin
- acetamides
- oxo
- eto
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Izgudrojums attiecas uz jaunu acetamīdu ar formulu (1a-c) iegūšanu un to lietošanu par pretkrampju līdzekļiem, kur: a) R=Ph, R1=Me; b) R=Ph, R1=i-Pr; c) R=EtO, R1=Et.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
LVP-20-49A LV15614A (lv) | 2020-07-30 | 2020-07-30 | 2-(2-okso-3-pirolin-1-il)acetamīdi kā pretkrampju līdzekļi |
CA3183942A CA3183942A1 (en) | 2020-07-30 | 2021-07-05 | 2-(2-oxo-3-pyrolin-1-yl)acetamides as anticonvulsants |
PCT/IB2021/055990 WO2022023839A1 (en) | 2020-07-30 | 2021-07-05 | 2-(2-oxo-3-pyrolin-1-yl)acetamides as anticonvulsants |
DKPA202270605A DK202270605A1 (en) | 2020-07-30 | 2022-12-13 | 2-(2-oxo-3-pyrolin-1-yl)acetamides as anticonvulsants |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
LVP-20-49A LV15614A (lv) | 2020-07-30 | 2020-07-30 | 2-(2-okso-3-pirolin-1-il)acetamīdi kā pretkrampju līdzekļi |
Publications (1)
Publication Number | Publication Date |
---|---|
LV15614A true LV15614A (lv) | 2022-02-20 |
Family
ID=77021675
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LVP-20-49A LV15614A (lv) | 2020-07-30 | 2020-07-30 | 2-(2-okso-3-pirolin-1-il)acetamīdi kā pretkrampju līdzekļi |
Country Status (4)
Country | Link |
---|---|
CA (1) | CA3183942A1 (lv) |
DK (1) | DK202270605A1 (lv) |
LV (1) | LV15614A (lv) |
WO (1) | WO2022023839A1 (lv) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008132142A2 (en) * | 2007-04-27 | 2008-11-06 | Ucb Pharma S.A. | New heterocyclic derivatives useful for the treatment of cns disorders |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0004297D0 (en) | 2000-02-23 | 2000-04-12 | Ucb Sa | 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses |
EP2147911A1 (en) | 2008-07-24 | 2010-01-27 | ZaCh System S.p.A. | Process for the preparation of levetiracetam |
CN102924357A (zh) * | 2011-08-09 | 2013-02-13 | 重庆圣华曦药业股份有限公司 | 奥拉西坦中间体的制备方法 |
RU2480214C1 (ru) * | 2011-09-22 | 2013-04-27 | Валентина Ивановна Ахапкина | Состав, обладающий модуляторной активностью с соразмерным влиянием, фармацевтическая субстанция (варианты), применение фармацевтической субстанции, фармацевтическая и парафармацевтическая композиция (варианты), способ получения фармацевтических составов |
WO2017076738A1 (en) | 2015-11-03 | 2017-05-11 | Ucb Biopharma Sprl | Process for preparing brivaracetam |
US10556863B1 (en) * | 2016-10-24 | 2020-02-11 | Chongqing Ruzer Pharmaceutical Company Limited | Crystalline form of (R)-4-hydroxy-2-oxo-1-pyrrolidineacetamide, preparation method therefor and use thereof |
-
2020
- 2020-07-30 LV LVP-20-49A patent/LV15614A/lv unknown
-
2021
- 2021-07-05 CA CA3183942A patent/CA3183942A1/en active Pending
- 2021-07-05 WO PCT/IB2021/055990 patent/WO2022023839A1/en active Application Filing
-
2022
- 2022-12-13 DK DKPA202270605A patent/DK202270605A1/en unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008132142A2 (en) * | 2007-04-27 | 2008-11-06 | Ucb Pharma S.A. | New heterocyclic derivatives useful for the treatment of cns disorders |
Also Published As
Publication number | Publication date |
---|---|
DK202270605A1 (en) | 2022-12-22 |
CA3183942A1 (en) | 2022-02-03 |
WO2022023839A1 (en) | 2022-02-03 |
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