NZ548255A - Modified human interferon polypeptides and their uses - Google Patents

Modified human interferon polypeptides and their uses

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Publication number
NZ548255A
NZ548255A NZ548255A NZ54825505A NZ548255A NZ 548255 A NZ548255 A NZ 548255A NZ 548255 A NZ548255 A NZ 548255A NZ 54825505 A NZ54825505 A NZ 54825505A NZ 548255 A NZ548255 A NZ 548255A
Authority
NZ
New Zealand
Prior art keywords
hlfn
amino acid
polypeptide
hlfn polypeptide
naturally encoded
Prior art date
Application number
NZ548255A
Other languages
English (en)
Inventor
Ho Sung Cho
Thomas Daniel
Putnam Anna-Maria A Hays
Troy Wilson
Original Assignee
Ambrx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ambrx Inc filed Critical Ambrx Inc
Publication of NZ548255A publication Critical patent/NZ548255A/en

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    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1808Epidermal growth factor [EGF] urogastrone
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    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
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    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
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    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C07K14/61Growth hormone [GH], i.e. somatotropin
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    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32Polymers modified by chemical after-treatment
    • C08G65/329Polymers modified by chemical after-treatment with organic compounds
    • C08G65/333Polymers modified by chemical after-treatment with organic compounds containing nitrogen
    • C08G65/33396Polymers modified by chemical after-treatment with organic compounds containing nitrogen having oxygen in addition to nitrogen
    • GPHYSICS
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    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6875Nucleoproteins
    • GPHYSICS
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    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value

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  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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NZ548255A 2004-02-02 2005-01-28 Modified human interferon polypeptides and their uses NZ548255A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US54152804P 2004-02-02 2004-02-02
US58117504P 2004-06-18 2004-06-18
US58088504P 2004-06-18 2004-06-18
US58131404P 2004-06-18 2004-06-18
US63861604P 2004-12-22 2004-12-22
PCT/US2005/002599 WO2005074524A2 (en) 2004-02-02 2005-01-28 Modified human interferon polypeptides and their uses

Publications (1)

Publication Number Publication Date
NZ548255A true NZ548255A (en) 2010-10-29

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ID=34842043

Family Applications (4)

Application Number Title Priority Date Filing Date
NZ548256A NZ548256A (en) 2004-02-02 2005-01-28 Modified human four helical bundle polypeptides and their uses
NZ548257A NZ548257A (en) 2004-02-02 2005-01-28 Modified human growth hormone polypeptides and their uses
NZ548255A NZ548255A (en) 2004-02-02 2005-01-28 Modified human interferon polypeptides and their uses
NZ586034A NZ586034A (en) 2004-02-02 2005-01-28 Modified human growth hormone polypeptides and their uses

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NZ548256A NZ548256A (en) 2004-02-02 2005-01-28 Modified human four helical bundle polypeptides and their uses
NZ548257A NZ548257A (en) 2004-02-02 2005-01-28 Modified human growth hormone polypeptides and their uses

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Application Number Title Priority Date Filing Date
NZ586034A NZ586034A (en) 2004-02-02 2005-01-28 Modified human growth hormone polypeptides and their uses

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US (15) US8906676B2 (enExample)
EP (4) EP2327724A3 (enExample)
JP (3) JP4896745B2 (enExample)
KR (3) KR20070007086A (enExample)
CN (1) CN103755800B (enExample)
AT (1) ATE546463T1 (enExample)
AU (5) AU2005209926B2 (enExample)
BR (3) BRPI0507169A (enExample)
CA (3) CA2553035A1 (enExample)
GB (3) GB2429207A (enExample)
IL (3) IL176594A0 (enExample)
MX (3) MXPA06008507A (enExample)
NZ (4) NZ548256A (enExample)
SG (1) SG135176A1 (enExample)
WO (3) WO2005074546A2 (enExample)

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EP1539960B1 (en) * 2002-09-09 2010-04-28 Hanall Pharmaceutical Co., Ltd. Protease-resistant modified interferon alpha polypeptides
US20070105770A1 (en) * 2004-01-21 2007-05-10 Novo Nordisk A/S Transglutaminase mediated conjugation of peptides
BRPI0507169A (pt) 2004-02-02 2007-06-26 Ambrx Inc polipeptìdeos do hormÈnio de crescimento humano modificados e seu usos
EP1584680A1 (en) * 2004-04-08 2005-10-12 Boehringer Ingelheim Austria GmbH Fed-batch fermentation process for the production of plasmid DNA
US20050287639A1 (en) 2004-05-17 2005-12-29 California Institute Of Technology Methods of incorporating amino acid analogs into proteins
CA2568952C (en) 2004-06-18 2019-05-21 Ambrx, Inc. Novel antigen-binding polypeptides and their uses
US7638299B2 (en) 2004-07-21 2009-12-29 Ambrx, Inc. Biosynthetic polypeptides utilizing non-naturally encoded amino acids
AU2009212311B8 (en) * 2004-07-21 2013-05-30 Ambrx, Inc. Modified leptin polypeptides and their uses
JP2008517033A (ja) * 2004-10-18 2008-05-22 ノボ ノルディスク アクティーゼルスカブ オキシム、チアゾリジン、ジチアン、ジチオランまたはヒドラゾンが連結した成長ホルモンの類似体の作製方法
US7998930B2 (en) 2004-11-04 2011-08-16 Hanall Biopharma Co., Ltd. Modified growth hormones
US8802820B2 (en) 2004-11-12 2014-08-12 Xencor, Inc. Fc variants with altered binding to FcRn
CA2587617C (en) 2004-11-12 2011-02-01 Xencor, Inc. Fc variants with altered binding to fcrn
EP1833993A4 (en) 2004-12-22 2009-07-22 Ambrx Inc HUMAN GROWTH HORMONE FORMULATIONS COMPRISING AN AMINO ACID CODED NON-NATURALLY
CA2590462C (en) * 2004-12-22 2017-02-28 Ambrx, Inc. Methods for expression and purification of recombinant human growth hormone
ZA200704926B (en) * 2004-12-22 2008-12-31 Ambrx Inc Modified human growth hormone
BRPI0519568C8 (pt) 2004-12-22 2022-06-14 Ambrx Inc Aminoacil-trna sintetase (rs), composições que compreendem a dita aminoacil-trna sintetase, célula de levedura, célula fúngica, célula não eucariótica, vetor que codifica uma rs, polinucleotídeo e ainda método para produzir um polipeptídeo em uma célula com um aminoácido selecionado em uma posição especificada
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