HK1217720A1 - 選擇性遞送分子及使用方法 - Google Patents
選擇性遞送分子及使用方法Info
- Publication number
- HK1217720A1 HK1217720A1 HK16105781.4A HK16105781A HK1217720A1 HK 1217720 A1 HK1217720 A1 HK 1217720A1 HK 16105781 A HK16105781 A HK 16105781A HK 1217720 A1 HK1217720 A1 HK 1217720A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- methods
- selective delivery
- delivery molecules
- molecules
- selective
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0032—Methine dyes, e.g. cyanine dyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
- A61K49/0054—Macromolecular compounds, i.e. oligomers, polymers, dendrimers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
- A61K49/0056—Peptides, proteins, polyamino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/14—Peptides, e.g. proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361758680P | 2013-01-30 | 2013-01-30 | |
PCT/US2014/013942 WO2014120974A1 (en) | 2013-01-30 | 2014-01-30 | Selective delivery molecules and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1217720A1 true HK1217720A1 (zh) | 2017-01-20 |
Family
ID=51262954
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16105781.4A HK1217720A1 (zh) | 2013-01-30 | 2016-05-20 | 選擇性遞送分子及使用方法 |
Country Status (11)
Country | Link |
---|---|
US (4) | US9782498B2 (zh) |
EP (1) | EP2951210A4 (zh) |
JP (1) | JP6508781B2 (zh) |
KR (2) | KR102363779B1 (zh) |
CN (1) | CN105102484B (zh) |
AU (1) | AU2014212308B2 (zh) |
CA (2) | CA3128911C (zh) |
EA (1) | EA031930B1 (zh) |
HK (1) | HK1217720A1 (zh) |
MX (1) | MX366375B (zh) |
WO (1) | WO2014120974A1 (zh) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3026701C (en) | 2009-03-02 | 2023-04-18 | Massachusetts Institute Of Technology | Methods and products for in vivo enzyme profiling |
ES2881535T3 (es) | 2011-03-15 | 2021-11-29 | Massachusetts Inst Technology | Detección multiplexada con indicadores codificados con isótopos |
US9278144B2 (en) | 2011-07-29 | 2016-03-08 | Avelas Biosciences, Inc. | Selective delivery molecules and methods of use |
WO2014120974A1 (en) * | 2013-01-30 | 2014-08-07 | Avelas Biosciences, Inc. | Selective delivery molecules and methods of use |
CA2994871A1 (en) | 2015-08-18 | 2017-02-23 | Aspyrian Therapeutics, Inc. | Phthalocyanine dye conjugates and their storage |
EP3337514B8 (en) | 2015-08-18 | 2022-04-06 | Rakuten Medical, Inc. | Composition comprising a conjugate comprising a phthalocyanine dye linked to a targeting molecule for photoimmunotherapy |
WO2017091568A1 (en) | 2015-11-23 | 2017-06-01 | Bristol-Myers Squibb Company | Additive systems for use in protein pegylation |
WO2017177115A1 (en) | 2016-04-08 | 2017-10-12 | Massachusetts Institute Of Technology | Methods to specifically profile protease activity at lymph nodes |
CA3022928A1 (en) | 2016-05-05 | 2017-11-09 | Massachusetts Institute Of Technology | Methods and uses for remotely triggered protease activity measurements |
AU2018248327A1 (en) | 2017-04-07 | 2019-10-17 | Massachusetts Institute Of Technology | Methods to spatially profile protease activity in tissue and sections |
WO2019204363A2 (en) * | 2018-04-16 | 2019-10-24 | Avelas Biosciences, Inc. | Selective delivery of therapeutic and imaging agents |
US11835522B2 (en) | 2019-01-17 | 2023-12-05 | Massachusetts Institute Of Technology | Sensors for detecting and imaging of cancer metastasis |
JP2022527941A (ja) | 2019-03-29 | 2022-06-07 | ラクテン・メディカル,インコーポレイテッド | 光免疫療法のための方法および関連バイオマーカー |
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US4439356A (en) | 1981-03-03 | 1984-03-27 | Syva Company | Unsymmetrical fluorescein derivatives |
US4496542A (en) | 1981-03-30 | 1985-01-29 | Usv Pharmaceutical Corporation | N-substituted-amido-amino acids |
US4507389A (en) | 1982-12-16 | 1985-03-26 | Monsanto Company | Determination of collagenase by reacting with peptide substrates |
US4466919A (en) | 1982-12-16 | 1984-08-21 | Monsanto Company | Peptide substrates for mammalian collagenase |
US5330900A (en) | 1987-12-31 | 1994-07-19 | Tropix, Inc. | Chemiluminescent 3-(substituted adamant-2'-ylidene) 1,2-dioxetanes |
US5066580A (en) | 1988-08-31 | 1991-11-19 | Becton Dickinson And Company | Xanthene dyes that emit to the red of fluorescein |
GB8927722D0 (en) | 1989-12-07 | 1990-02-07 | British Bio Technology | Proteins and nucleic acids |
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NZ601659A (en) | 2008-09-26 | 2014-02-28 | Ambrx Inc | Modified animal erythropoietin polypeptides and their uses |
KR101095841B1 (ko) | 2009-02-19 | 2011-12-21 | 주식회사 나이벡 | 표적 선택적 세포/조직 투과기능 활성을 가지는 펩타이드 및 그 용도 |
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WO2010121023A2 (en) | 2009-04-15 | 2010-10-21 | The Regents Of The University Of California | Peptides and aptamers for targeting of neuron or nerves |
US9808532B2 (en) | 2009-07-15 | 2017-11-07 | The Regents Of The University Of California | Peptides whose uptake in cells is controllable |
JP5580625B2 (ja) | 2010-03-03 | 2014-08-27 | 住友化学株式会社 | メタンスルホン酸アルキルエステル溶液の製造方法 |
JP5646923B2 (ja) | 2010-09-03 | 2014-12-24 | 矢崎総業株式会社 | 車両用表示装置及び車両用表示システム |
TR201901259T4 (tr) * | 2011-02-10 | 2019-02-21 | Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts | Karaciğere özgü tanı için hidrofobik modifiye peptidler. |
US9278144B2 (en) | 2011-07-29 | 2016-03-08 | Avelas Biosciences, Inc. | Selective delivery molecules and methods of use |
US10029017B2 (en) | 2013-01-29 | 2018-07-24 | The Regents Of The University Of California | Pretargeted activatable cell penetrating peptide with intracellularly releasable prodrug |
WO2014120974A1 (en) | 2013-01-30 | 2014-08-07 | Avelas Biosciences, Inc. | Selective delivery molecules and methods of use |
US20160082119A1 (en) | 2013-04-22 | 2016-03-24 | Avelas Biosciences, Inc. | Selective drug delivery compositions and methods of use |
-
2014
- 2014-01-30 WO PCT/US2014/013942 patent/WO2014120974A1/en active Application Filing
- 2014-01-30 CA CA3128911A patent/CA3128911C/en active Active
- 2014-01-30 EP EP14746840.9A patent/EP2951210A4/en active Pending
- 2014-01-30 US US14/764,681 patent/US9782498B2/en active Active
- 2014-01-30 KR KR1020217021841A patent/KR102363779B1/ko active IP Right Grant
- 2014-01-30 KR KR1020157022729A patent/KR102278630B1/ko active IP Right Grant
- 2014-01-30 EA EA201591284A patent/EA031930B1/ru unknown
- 2014-01-30 CA CA2899448A patent/CA2899448C/en active Active
- 2014-01-30 JP JP2015556140A patent/JP6508781B2/ja not_active Expired - Fee Related
- 2014-01-30 CN CN201480019153.9A patent/CN105102484B/zh active Active
- 2014-01-30 MX MX2015009858A patent/MX366375B/es active IP Right Grant
- 2014-01-30 AU AU2014212308A patent/AU2014212308B2/en active Active
-
2016
- 2016-05-20 HK HK16105781.4A patent/HK1217720A1/zh unknown
-
2017
- 2017-08-24 US US15/685,942 patent/US10226539B2/en active Active
-
2019
- 2019-01-31 US US16/264,296 patent/US11052160B2/en active Active
-
2021
- 2021-05-03 US US17/302,453 patent/US20220257800A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2951210A1 (en) | 2015-12-09 |
US20220257800A1 (en) | 2022-08-18 |
KR102363779B1 (ko) | 2022-02-15 |
WO2014120974A1 (en) | 2014-08-07 |
JP2016516000A (ja) | 2016-06-02 |
US20190151481A1 (en) | 2019-05-23 |
KR20210090739A (ko) | 2021-07-20 |
EA201591284A1 (ru) | 2016-04-29 |
US9782498B2 (en) | 2017-10-10 |
EP2951210A4 (en) | 2016-09-21 |
US20150359908A1 (en) | 2015-12-17 |
MX2015009858A (es) | 2016-02-16 |
CA3128911A1 (en) | 2014-08-07 |
KR20150111963A (ko) | 2015-10-06 |
JP6508781B2 (ja) | 2019-05-08 |
KR102278630B1 (ko) | 2021-07-16 |
CN105102484B (zh) | 2020-03-10 |
EA031930B1 (ru) | 2019-03-29 |
US11052160B2 (en) | 2021-07-06 |
US10226539B2 (en) | 2019-03-12 |
CN105102484A (zh) | 2015-11-25 |
CA2899448C (en) | 2021-10-26 |
AU2014212308A1 (en) | 2015-08-13 |
AU2014212308B2 (en) | 2018-08-09 |
MX366375B (es) | 2019-07-05 |
CA3128911C (en) | 2023-10-17 |
US20180000971A1 (en) | 2018-01-04 |
CA2899448A1 (en) | 2014-08-07 |
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