MX345559B - Produccion mejorada de lipidos que contienen acidos grasos polienoicos por cultivos de alta densidad de microbios eucarioticos en fermentadores. - Google Patents

Produccion mejorada de lipidos que contienen acidos grasos polienoicos por cultivos de alta densidad de microbios eucarioticos en fermentadores.

Info

Publication number
MX345559B
MX345559B MX2012006312A MX2012006312A MX345559B MX 345559 B MX345559 B MX 345559B MX 2012006312 A MX2012006312 A MX 2012006312A MX 2012006312 A MX2012006312 A MX 2012006312A MX 345559 B MX345559 B MX 345559B
Authority
MX
Mexico
Prior art keywords
fatty acids
fermentors
high density
lipids containing
enhanced production
Prior art date
Application number
MX2012006312A
Other languages
English (en)
Inventor
R Barclay William
M Reucker Craig
Dimasi Don
M Hansen Jon
J Mirrasoul Peter
B Bailey Richard
Kaneko Tatsuo
T Weeder George Iii
Original Assignee
Dsm Ip Assets B V *
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22653135&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX345559(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dsm Ip Assets B V * filed Critical Dsm Ip Assets B V *
Publication of MX345559B publication Critical patent/MX345559B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/065—Microorganisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C11B1/10—Production of fats or fatty oils from raw materials by extracting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434—Docosahexenoic acids [DHA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Birds (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Insects & Arthropods (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invención se refiere a un proceso para producir lípidos que contienen ácidos graos poliinsaturados de microorganismos del orden Thraustochytriales mediante la realización de una fermentación de los microorganismos en un medio de fermentación que comprende una fuente de carbono, el proceso que comprende: a) proporcionar el medio de fermentación que comprende la fuente de carbono a una temperatura de al menos 20°C y un pH de aproximadamente 5 a aproximadamente 11; b) añadir los microorganismos al medio de fermentación; c) añadir una cantidad adicional de la fuente de carbono al medio de fermentación en un proceso de alimentación por lotes para aumentar la densidad de la biomasa del medio de fermentación a por lo menos 100 g/l sobre una base de peso celular seco, en donde la cantidad adicional de la fuente de carbono se añadió a una tasa suficiente para aumentar la densidad de la biomasa del medio de fermentación de por lo menos 100 g/l; y d) recuperar los lípidos del medio de fermentación; en donde el uso principal de la fuente de carbono por los microorganismos es para producir los lípidos cuando la densidad de la biomasa del medio de fermentación es de al menos 100 g/l sobre una base de peso celular seco; en donde los lípidos contienen ácidos grasos poliinsaturados, y en donde los lípidos son al menos 20% de la biomasa cuando la densidad de la biomasa es por lo menos 100 g/l.
MX2012006312A 2000-01-28 2001-01-26 Produccion mejorada de lipidos que contienen acidos grasos polienoicos por cultivos de alta densidad de microbios eucarioticos en fermentadores. MX345559B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17858800P 2000-01-28 2000-01-28
PCT/US2001/002715 WO2001054510A1 (en) 2000-01-28 2001-01-26 Enhanced production of lipids containing polyenoic fatty acids by high density cultures of eukaryotic microbes in fermentors

Publications (1)

Publication Number Publication Date
MX345559B true MX345559B (es) 2017-02-03

Family

ID=22653135

Family Applications (2)

Application Number Title Priority Date Filing Date
MXPA02007321A MXPA02007321A (es) 2000-01-28 2001-01-26 Produccion mejorada de lipidos que contienen acidos grasos polienoicos por cultivos de alta densidad de microbios eucarioticos en fermentadores.
MX2012006312A MX345559B (es) 2000-01-28 2001-01-26 Produccion mejorada de lipidos que contienen acidos grasos polienoicos por cultivos de alta densidad de microbios eucarioticos en fermentadores.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MXPA02007321A MXPA02007321A (es) 2000-01-28 2001-01-26 Produccion mejorada de lipidos que contienen acidos grasos polienoicos por cultivos de alta densidad de microbios eucarioticos en fermentadores.

Country Status (26)

Country Link
US (18) US6607900B2 (es)
EP (7) EP1251744B2 (es)
JP (9) JP2004501603A (es)
KR (6) KR20070073986A (es)
CN (8) CN101003821A (es)
AT (1) ATE374531T1 (es)
AU (4) AU785124B2 (es)
BR (1) BRPI0107832B1 (es)
CA (3) CA2760879C (es)
CY (1) CY1107114T1 (es)
CZ (1) CZ301130B6 (es)
DE (2) DE60130737T3 (es)
DK (1) DK1251744T4 (es)
ES (4) ES2654384T3 (es)
HU (1) HUP0301794A3 (es)
IL (3) IL150770A0 (es)
MX (2) MXPA02007321A (es)
NO (1) NO20023588L (es)
NZ (1) NZ520420A (es)
PL (1) PL362620A1 (es)
PT (1) PT1251744E (es)
RU (1) RU2326171C2 (es)
TR (1) TR200302163T3 (es)
TW (3) TWI310788B (es)
WO (1) WO2001054510A1 (es)
ZA (1) ZA200205957B (es)

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