JP5133416B2 - １’，３’−二置換−４−フェニル−３，４，５，６−テトラヒドロ−２ｈ，１’ｈ−［１，４’］ビピリジニル−２’−オン - Google Patents

１’，３’−二置換−４−フェニル−３，４，５，６−テトラヒドロ−２ｈ，１’ｈ−［１，４’］ビピリジニル−２’−オン Download PDF

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JP5133416B2
JP5133416B2 JP2010524405A JP2010524405A JP5133416B2 JP 5133416 B2 JP5133416 B2 JP 5133416B2 JP 2010524405 A JP2010524405 A JP 2010524405A JP 2010524405 A JP2010524405 A JP 2010524405A JP 5133416 B2 JP5133416 B2 JP 5133416B2
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JP2010539121A5 (OSRAM
JP2010539121A (ja
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ホセ， マリア シドゥ−ヌネズ，
アンドレ， アヴェリノ トラバンコ−スアレス，
グレゴール， ジェームス マクドナルド，
ギラーム， アルバート， ジャックス ドゥベーイ，
ロバート， ヨハネス リッツェンス，
テリー， パトリック フィン，
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オルソー−マクニール−ジャンセン ファーマシューティカルズ， インコーポレイテッド．
アデックス ファーマ エス エー
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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JP2010524405A 2007-09-14 2008-09-12 １’，３’−二置換−４−フェニル−３，４，５，６−テトラヒドロ−２ｈ，１’ｈ−［１，４’］ビピリジニル−２’−オン Active JP5133416B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07116390 2007-09-14
EP07116390.1 2007-09-14
PCT/EP2008/007551 WO2009033704A1 (en) 2007-09-14 2008-09-12 1',3'-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2h, 1'h-[1, 4'] bipyridinyl-2'-ones

Publications (3)

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JP2010539121A JP2010539121A (ja) 2010-12-16
JP2010539121A5 JP2010539121A5 (OSRAM) 2012-11-01
JP5133416B2 true JP5133416B2 (ja) 2013-01-30

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US (6) US9114138B2 (OSRAM)
EP (1) EP2203439B1 (OSRAM)
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KR (2) KR101533440B1 (OSRAM)
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GB0420722D0 (en) 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
AR059898A1 (es) 2006-03-15 2008-05-07 Janssen Pharmaceutica Nv Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2
TW200900065A (en) 2007-03-07 2009-01-01 Janssen Pharmaceutica Nv 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives
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