IT1298155B1 - Composti pirimidin 3-ossido per il trattamento delle patologie muscolo-scheletriche, in particolare per il trattamento della - Google Patents
Composti pirimidin 3-ossido per il trattamento delle patologie muscolo-scheletriche, in particolare per il trattamento dellaInfo
- Publication number
- IT1298155B1 IT1298155B1 ITMI980086A IT1298155B1 IT 1298155 B1 IT1298155 B1 IT 1298155B1 IT MI980086 A ITMI980086 A IT MI980086A IT 1298155 B1 IT1298155 B1 IT 1298155B1
- Authority
- IT
- Italy
- Prior art keywords
- treatment
- pyridid
- muscle
- oxide compounds
- skeletal pathologies
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI980086 IT1298155B1 (it) | 1998-01-19 | 1998-01-19 | Composti pirimidin 3-ossido per il trattamento delle patologie muscolo-scheletriche, in particolare per il trattamento della |
PCT/EP1999/000269 WO1999036072A1 (en) | 1998-01-19 | 1999-01-18 | Pyrimidin 3-oxide compounds suitable for the treatment of pathologies of the skeletal muscle, in particular for the treatment of the hypokalemic paralysis |
EP99904793A EP1049473A1 (en) | 1998-01-19 | 1999-01-18 | Pyrimidin 3-oxide compounds suitable for the treatment of pathologies of the skeletal muscle, in particular for the treatment of the hypokalemic paralysis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI980086 IT1298155B1 (it) | 1998-01-19 | 1998-01-19 | Composti pirimidin 3-ossido per il trattamento delle patologie muscolo-scheletriche, in particolare per il trattamento della |
Publications (2)
Publication Number | Publication Date |
---|---|
ITMI980086A1 ITMI980086A1 (it) | 1999-07-19 |
IT1298155B1 true IT1298155B1 (it) | 1999-12-20 |
Family
ID=11378623
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI980086 IT1298155B1 (it) | 1998-01-19 | 1998-01-19 | Composti pirimidin 3-ossido per il trattamento delle patologie muscolo-scheletriche, in particolare per il trattamento della |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1049473A1 (it) |
IT (1) | IT1298155B1 (it) |
WO (1) | WO1999036072A1 (it) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1323432B1 (en) * | 2001-12-28 | 2005-08-24 | Sandra Cosci | Complexes of cyclodextrins with potassium ion homeostasis regulators |
AR059898A1 (es) | 2006-03-15 | 2008-05-07 | Janssen Pharmaceutica Nv | Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2 |
TW200845978A (en) | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
TW200900065A (en) | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
JP5133416B2 (ja) | 2007-09-14 | 2013-01-30 | オルソー−マクニール−ジャンセン ファーマシューティカルズ, インコーポレイテッド. | 1’,3’−二置換−4−フェニル−3,4,5,6−テトラヒドロ−2h,1’h−[1,4’]ビピリジニル−2’−オン |
US8691849B2 (en) | 2008-09-02 | 2014-04-08 | Janssen Pharmaceuticals, Inc. | 3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors |
WO2010060589A1 (en) | 2008-11-28 | 2010-06-03 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | Indole and benzoxazine derivatives as modulators of metabotropic glutamate receptors |
US8937060B2 (en) | 2009-05-12 | 2015-01-20 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo [4,3-A] pyridine derivatives and their use for the treatment of prevention of neurological and psychiatric disorders |
MY153913A (en) | 2009-05-12 | 2015-04-15 | Janssen Pharmaceuticals Inc | 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
EP2430031B1 (en) | 2009-05-12 | 2013-04-17 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
AU2011328195B2 (en) | 2010-11-08 | 2015-04-02 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
WO2012062750A1 (en) | 2010-11-08 | 2012-05-18 | Janssen Pharmaceuticals, Inc. | 1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS |
AU2011328203B2 (en) | 2010-11-08 | 2015-03-19 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
JO3368B1 (ar) | 2013-06-04 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2 |
JO3367B1 (ar) | 2013-09-06 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2 |
IL279202B2 (en) | 2014-01-21 | 2023-09-01 | Janssen Pharmaceutica Nv | Combinations containing positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic subtype 2 receptor and their use |
PL3431106T3 (pl) | 2014-01-21 | 2021-06-28 | Janssen Pharmaceutica Nv | Kombinacje zawierające pozytywne modulatory allosteryczne metabotropowego receptora glutaminergicznego podtypu 2 i ich zastosowanie |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2055376A1 (en) * | 1990-12-05 | 1992-06-06 | Gary J. Grover | Method of treating shock using a potassium channel activator |
-
1998
- 1998-01-19 IT ITMI980086 patent/IT1298155B1/it active IP Right Grant
-
1999
- 1999-01-18 WO PCT/EP1999/000269 patent/WO1999036072A1/en not_active Application Discontinuation
- 1999-01-18 EP EP99904793A patent/EP1049473A1/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP1049473A1 (en) | 2000-11-08 |
WO1999036072A1 (en) | 1999-07-22 |
ITMI980086A1 (it) | 1999-07-19 |
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