JP2010539121A5 - - Google Patents

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Publication number
JP2010539121A5
JP2010539121A5 JP2010524405A JP2010524405A JP2010539121A5 JP 2010539121 A5 JP2010539121 A5 JP 2010539121A5 JP 2010524405 A JP2010524405 A JP 2010524405A JP 2010524405 A JP2010524405 A JP 2010524405A JP 2010539121 A5 JP2010539121 A5 JP 2010539121A5
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JP
Japan
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disorder
group
nervous system
central nervous
epilepsy
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JP2010524405A
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English (en)
Japanese (ja)
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JP2010539121A (ja
JP5133416B2 (ja
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Priority claimed from PCT/EP2008/007551 external-priority patent/WO2009033704A1/en
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Publication of JP2010539121A5 publication Critical patent/JP2010539121A5/ja
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JP2010524405A 2007-09-14 2008-09-12 １’，３’−二置換−４−フェニル−３，４，５，６−テトラヒドロ−２ｈ，１’ｈ−［１，４’］ビピリジニル−２’−オン Active JP5133416B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07116390 2007-09-14
EP07116390.1 2007-09-14
PCT/EP2008/007551 WO2009033704A1 (en) 2007-09-14 2008-09-12 1',3'-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2h, 1'h-[1, 4'] bipyridinyl-2'-ones

Publications (3)

Publication Number Publication Date
JP2010539121A JP2010539121A (ja) 2010-12-16
JP2010539121A5 true JP2010539121A5 (OSRAM) 2012-11-01
JP5133416B2 JP5133416B2 (ja) 2013-01-30

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ID=39930548

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010524405A Active JP5133416B2 (ja) 2007-09-14 2008-09-12 １’，３’−二置換−４−フェニル−３，４，５，６−テトラヒドロ−２ｈ，１’ｈ−［１，４’］ビピリジニル−２’−オン

Country Status (29)

Country Link
US (6) US9114138B2 (OSRAM)
EP (1) EP2203439B1 (OSRAM)
JP (1) JP5133416B2 (OSRAM)
KR (2) KR101533440B1 (OSRAM)
CN (2) CN103342695B (OSRAM)
AR (1) AR068511A1 (OSRAM)
AT (1) ATE496906T1 (OSRAM)
AU (1) AU2008297878B2 (OSRAM)
BR (1) BRPI0816767B8 (OSRAM)
CA (1) CA2696948C (OSRAM)
CL (1) CL2008002745A1 (OSRAM)
CY (1) CY1111219T1 (OSRAM)
DE (1) DE602008004794D1 (OSRAM)
DK (1) DK2203439T3 (OSRAM)
EA (1) EA017648B1 (OSRAM)
ES (1) ES2356032T3 (OSRAM)
HR (1) HRP20110278T1 (OSRAM)
IL (2) IL204032A (OSRAM)
MX (1) MX2010002536A (OSRAM)
MY (1) MY152078A (OSRAM)
NZ (1) NZ584145A (OSRAM)
PL (1) PL2203439T3 (OSRAM)
PT (1) PT2203439E (OSRAM)
RS (1) RS51660B (OSRAM)
SI (1) SI2203439T1 (OSRAM)
TW (2) TWI445532B (OSRAM)
UA (1) UA100126C2 (OSRAM)
WO (1) WO2009033704A1 (OSRAM)
ZA (1) ZA201001151B (OSRAM)

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JP5852665B2 (ja) 2010-11-08 2016-02-03 ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド １，２，４−トリアゾロ［４，３−ａ］ピリジン誘導体およびｍＧｌｕＲ２受容体のポジティブアロステリックモジュレーターとしてのそれらの使用
PT2649069E (pt) 2010-11-08 2015-11-20 Janssen Pharmaceuticals Inc Derivados de 1,2,4-triazolo[4,3-a]piridina e sua utilização como moduladores alostéricos positivos de recetores mglur2
JO3368B1 (ar) 2013-06-04 2019-03-13 Janssen Pharmaceutica Nv مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2
JO3367B1 (ar) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
AU2015208233B2 (en) * 2014-01-21 2019-08-29 Janssen Pharmaceutica Nv Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use
ES2860298T3 (es) 2014-01-21 2021-10-04 Janssen Pharmaceutica Nv Combinaciones que comprenden moduladores alostéricos positivos del receptor glutamatérgico metabotrópico de subtipo 2 y su uso
TW201600522A (zh) * 2014-02-20 2016-01-01 赫孚孟拉羅股份公司 螺－唑酮
AU2015359352B2 (en) * 2014-12-11 2020-07-02 Janssen Pharmaceutica Nv 1,2,4-triazolo(4,3-a)pyridine compounds and their use as positive allosteric modulators of mGluR2 receptors
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