JP4105948B2 - プロテインキナーゼインヒビターとして有用なピラゾール化合物 - Google Patents

プロテインキナーゼインヒビターとして有用なピラゾール化合物 Download PDF

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JP4105948B2
JP4105948B2 JP2002526857A JP2002526857A JP4105948B2 JP 4105948 B2 JP4105948 B2 JP 4105948B2 JP 2002526857 A JP2002526857 A JP 2002526857A JP 2002526857 A JP2002526857 A JP 2002526857A JP 4105948 B2 JP4105948 B2 JP 4105948B2
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ring
optionally substituted
aliphatic
alkyl
membered
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JP2004512277A5 (enExample
JP2004512277A (ja
Inventor
ロバート デビース，
デビッド ベビントン，
ハーレイ ビンチ，
ロナルド ネグテル，
ジュリアン エム．シー． ゴレック，
サンジャイ パテル，
ジャン−ダミアン シャリアー，
デビッド ケイ，
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Vertex Pharmaceuticals Inc
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Vertex Pharmaceuticals Inc
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    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
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  • Organic Chemistry (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • Diabetes (AREA)
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  • Rheumatology (AREA)
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  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
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  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
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JP2002526857A 2000-09-15 2001-09-14 プロテインキナーゼインヒビターとして有用なピラゾール化合物 Expired - Fee Related JP4105948B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US23279500P 2000-09-15 2000-09-15
US25788700P 2000-12-21 2000-12-21
US28694901P 2001-04-27 2001-04-27
PCT/US2001/028792 WO2002022604A1 (en) 2000-09-15 2001-09-14 Pyrazole compounds useful as protein kinase inhibitors

Publications (3)

Publication Number Publication Date
JP2004512277A JP2004512277A (ja) 2004-04-22
JP2004512277A5 JP2004512277A5 (enExample) 2005-04-28
JP4105948B2 true JP4105948B2 (ja) 2008-06-25

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JP2002526857A Expired - Fee Related JP4105948B2 (ja) 2000-09-15 2001-09-14 プロテインキナーゼインヒビターとして有用なピラゾール化合物
JP2002526854A Expired - Fee Related JP4111824B2 (ja) 2000-09-15 2001-09-14 プロテインキナーゼインヒビターとして有用なピラゾール化合物
JP2002526855A Expired - Fee Related JP4105947B2 (ja) 2000-09-15 2001-09-14 プロテインキナーゼインヒビターとして有用なトリアゾール化合物
JP2002526859A Expired - Fee Related JP4105949B2 (ja) 2000-09-15 2001-09-14 プロテインキナーゼインヒビターとして有用なピラゾール化合物
JP2002526861A Pending JP2004509118A (ja) 2000-09-15 2001-09-14 プロテインキナーゼインヒビターとして有用なピラゾール化合物
JP2002526858A Pending JP2004509115A (ja) 2000-09-15 2001-09-14 プロテインキナーゼインヒビターとして有用なピラゾール化合物
JP2002526856A Expired - Fee Related JP4922539B2 (ja) 2000-09-15 2001-09-14 プロテインキナーゼインヒビターとして有用なピラゾール化合物
JP2002526860A Expired - Fee Related JP4170752B2 (ja) 2000-09-15 2001-09-14 プロテインキナーゼインヒビターとして有用なピラゾール化合物
JP2008015681A Pending JP2008115195A (ja) 2000-09-15 2008-01-25 プロテインキナーゼインヒビターとして有用なピラゾール化合物

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JP2002526854A Expired - Fee Related JP4111824B2 (ja) 2000-09-15 2001-09-14 プロテインキナーゼインヒビターとして有用なピラゾール化合物
JP2002526855A Expired - Fee Related JP4105947B2 (ja) 2000-09-15 2001-09-14 プロテインキナーゼインヒビターとして有用なトリアゾール化合物
JP2002526859A Expired - Fee Related JP4105949B2 (ja) 2000-09-15 2001-09-14 プロテインキナーゼインヒビターとして有用なピラゾール化合物
JP2002526861A Pending JP2004509118A (ja) 2000-09-15 2001-09-14 プロテインキナーゼインヒビターとして有用なピラゾール化合物
JP2002526858A Pending JP2004509115A (ja) 2000-09-15 2001-09-14 プロテインキナーゼインヒビターとして有用なピラゾール化合物
JP2002526856A Expired - Fee Related JP4922539B2 (ja) 2000-09-15 2001-09-14 プロテインキナーゼインヒビターとして有用なピラゾール化合物
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