HK1080090B - 肽的重构和糖缀合的方法 - Google Patents

肽的重构和糖缀合的方法 Download PDF

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Publication number
HK1080090B
HK1080090B HK06100136.9A HK06100136A HK1080090B HK 1080090 B HK1080090 B HK 1080090B HK 06100136 A HK06100136 A HK 06100136A HK 1080090 B HK1080090 B HK 1080090B
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HK
Hong Kong
Prior art keywords
peptide
independently selected
glycosyl
glycans
contacting
Prior art date
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HK06100136.9A
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English (en)
Chinese (zh)
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HK1080090A1 (en
Inventor
S.德弗里斯
S．德弗裡斯
D.佐普夫
R.拜尔
C．博维
D．海克斯
R．拜爾
陈希
C．博維
陳希
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诺和诺德公司
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Application filed by 诺和诺德公司 filed Critical 诺和诺德公司
Publication of HK1080090A1 publication Critical patent/HK1080090A1/xx
Publication of HK1080090B publication Critical patent/HK1080090B/zh

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6437—Coagulation factor VIIa (3.4.21.21)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
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